KR20240013728A - 지수 래디언스로 테더링된 연결된 증폭 - Google Patents
지수 래디언스로 테더링된 연결된 증폭 Download PDFInfo
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- KR20240013728A KR20240013728A KR1020237038170A KR20237038170A KR20240013728A KR 20240013728 A KR20240013728 A KR 20240013728A KR 1020237038170 A KR1020237038170 A KR 1020237038170A KR 20237038170 A KR20237038170 A KR 20237038170A KR 20240013728 A KR20240013728 A KR 20240013728A
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- C12Q2533/00—Reactions characterised by the enzymatic reaction principle used
- C12Q2533/10—Reactions characterised by the enzymatic reaction principle used the purpose being to increase the length of an oligonucleotide strand
- C12Q2533/107—Probe or oligonucleotide ligation
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- C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
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- C12Q2537/143—Multiplexing, i.e. use of multiple primers or probes in a single reaction, usually for simultaneously analyse of multiple analysis
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- C12Q2543/00—Reactions characterised by the reaction site, e.g. cell or chromosome
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- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/179—Nucleic acid detection characterized by the use of physical, structural and functional properties the label being a nucleic acid
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| US63/192,554 | 2021-05-24 | ||
| PCT/US2022/021826 WO2022250774A1 (en) | 2021-05-24 | 2022-03-24 | Linked amplification tethered with exponential radiance |
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| WO2025194315A1 (zh) * | 2024-03-18 | 2025-09-25 | 深圳华大智造科技股份有限公司 | 核酸检测方法及其应用 |
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| US5681697A (en) * | 1993-12-08 | 1997-10-28 | Chiron Corporation | Solution phase nucleic acid sandwich assays having reduced background noise and kits therefor |
| US8481268B2 (en) * | 1999-05-21 | 2013-07-09 | Illumina, Inc. | Use of microfluidic systems in the detection of target analytes using microsphere arrays |
| WO2011038403A1 (en) * | 2009-09-28 | 2011-03-31 | Yuling Luo | Methods of detecting nucleic acid sequences with high specificity |
| US20120004132A1 (en) * | 2010-07-02 | 2012-01-05 | Affymetrix, Inc. | Detection of Nucleic Acids and Proteins |
| US8658361B2 (en) * | 2010-10-21 | 2014-02-25 | Advanced Cell Diagnostics, Inc. | Ultra sensitive method for in situ detection of nucleic acids |
| CN103649331A (zh) * | 2011-02-15 | 2014-03-19 | 莱卡生物系统纽卡斯尔有限责任公司 | 用于mrna的定位的原位检测的方法 |
| CN116200462B (zh) * | 2016-05-16 | 2025-10-03 | 布鲁克空间生物学公司 | 用于检测样品中目标核酸的方法 |
| EP4556575A3 (en) * | 2016-11-21 | 2025-10-08 | Bruker Spatial Biology, Inc. | A method for sequencing nucleic acids |
| CN118345145A (zh) * | 2016-12-09 | 2024-07-16 | 乌尔蒂维尤股份有限公司 | 用于使用标记的核酸成像剂进行多路复用成像的改进方法 |
| EP4063519B1 (en) * | 2018-04-09 | 2023-09-13 | Advanced Cell Diagnostics, Inc. | Methods to further enhance signal amplification for the in situ detection of nucleic acids |
| EP3894583A4 (en) * | 2018-12-13 | 2022-11-09 | President and Fellows of Harvard College | AMPLIFICATION METHODS AND SYSTEMS FOR MERFISH AND OTHER APPLICATIONS |
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| CA3213718A1 (en) | 2022-12-01 |
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