JP2024520805A5 - - Google Patents

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Publication number
JP2024520805A5
JP2024520805A5 JP2023575831A JP2023575831A JP2024520805A5 JP 2024520805 A5 JP2024520805 A5 JP 2024520805A5 JP 2023575831 A JP2023575831 A JP 2023575831A JP 2023575831 A JP2023575831 A JP 2023575831A JP 2024520805 A5 JP2024520805 A5 JP 2024520805A5
Authority
JP
Japan
Prior art keywords
composition
alzheimer
disease
antigen
binding fragment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023575831A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024520805A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/033122 external-priority patent/WO2022261510A1/en
Publication of JP2024520805A publication Critical patent/JP2024520805A/ja
Publication of JP2024520805A5 publication Critical patent/JP2024520805A5/ja
Pending legal-status Critical Current

Links

JP2023575831A 2021-06-11 2022-06-10 アルツハイマー病の治療のための神経活性ステロイド Pending JP2024520805A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202163209929P 2021-06-11 2021-06-11
US63/209,929 2021-06-11
US202163289081P 2021-12-13 2021-12-13
US63/289,081 2021-12-13
US202263321598P 2022-03-18 2022-03-18
US63/321,598 2022-03-18
PCT/US2022/033122 WO2022261510A1 (en) 2021-06-11 2022-06-10 Neuroactive steroid for the treatment of alzheimer's disease

Publications (2)

Publication Number Publication Date
JP2024520805A JP2024520805A (ja) 2024-05-24
JP2024520805A5 true JP2024520805A5 (https=) 2025-06-30

Family

ID=82361350

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023575831A Pending JP2024520805A (ja) 2021-06-11 2022-06-10 アルツハイマー病の治療のための神経活性ステロイド

Country Status (9)

Country Link
US (1) US20250319105A1 (https=)
EP (1) EP4351588A1 (https=)
JP (1) JP2024520805A (https=)
KR (1) KR20240035444A (https=)
AU (1) AU2022291395A1 (https=)
CA (1) CA3223179A1 (https=)
IL (1) IL309208A (https=)
MX (1) MX2023014719A (https=)
WO (1) WO2022261510A1 (https=)

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Publication number Priority date Publication date Assignee Title
EP3828194B1 (en) 2015-07-06 2025-04-16 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
EP4704905A1 (en) * 2023-05-02 2026-03-11 Sage Therapeutics, LLC Lymphatic system-targeting compounds
TW202508603A (zh) * 2023-05-02 2025-03-01 美商賽吉醫療公司 神經活性類固醇調配物及其使用方法
WO2025021195A1 (zh) * 2023-07-27 2025-01-30 珂阑(上海)医药科技有限公司 甾类化合物、其制备方法和应用
WO2025020190A1 (zh) * 2023-07-27 2025-01-30 珂阑(上海)医药科技有限公司 甾类化合物、其制备方法和应用
WO2025020191A1 (zh) * 2023-07-27 2025-01-30 珂阑(上海)医药科技有限公司 甾类化合物、其制备方法和应用

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040132101A1 (en) 2002-09-27 2004-07-08 Xencor Optimized Fc variants and methods for their generation
KR20080073293A (ko) 2005-10-14 2008-08-08 메디뮨 엘엘씨 항체 라이브러리의 세포 디스플레이
WO2008081008A1 (en) 2007-01-05 2008-07-10 University Of Zurich Method of providing disease-specific binding molecules and targets
HRP20140049T1 (hr) 2007-01-05 2014-02-28 University Of Zürich Anti beta-amiloid antitijela i njihova upotreba
HUE030100T2 (en) 2010-02-19 2017-04-28 Xencor Inc New CTLA4-IG immunoadhesins
ES2758994T3 (es) 2010-11-05 2020-05-07 Zymeworks Inc Diseño anticuerpo heterodimérico estable con mutaciones en el dominio Fc
CA2848212C (en) 2011-09-08 2022-03-29 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
AP2014007606A0 (en) 2011-10-07 2014-05-31 Takeda Pharmaceutical 1-Arylcarbonyl-4-oxy-piperidine compounds useful for the treatment of neurodegenerative diseases
JP6249952B2 (ja) 2012-10-16 2017-12-20 武田薬品工業株式会社 複素環化合物
HUE039922T2 (hu) 2012-12-11 2019-02-28 Takeda Pharmaceuticals Co Heterociklusos vegyületek
PT2968369T (pt) 2013-03-13 2018-12-05 Sage Therapeutics Inc Esteroides neuroativos e métodos para o seu uso
JP6272833B2 (ja) 2013-04-04 2018-01-31 武田薬品工業株式会社 複素環化合物
EP3102230B1 (en) * 2014-02-08 2021-04-28 F. Hoffmann-La Roche AG Methods of treating alzheimer's disease
US10259840B2 (en) 2014-06-18 2019-04-16 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
MA41115A (fr) 2014-12-02 2017-10-10 Biogen Int Neuroscience Gmbh Procédé de traitement de la maladie d'alzheimer
CA2991311C (en) 2015-07-06 2025-05-06 Sage Therapeutics, Inc. OXYSTEROLS AND THEIR METHODS OF USE
EP3828194B1 (en) 2015-07-06 2025-04-16 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
HUE071964T2 (hu) 2015-07-06 2025-10-28 Sage Therapeutics Inc Oxiszterolok és alkalmazási eljárásaik
US10562881B2 (en) 2015-10-16 2020-02-18 Takeda Pharmaceutical Company Limited Method for producing heterocyclic compound
SMT202200300T1 (it) 2016-04-01 2022-09-14 Sage Therapeutics Inc Ossisteroli e relativi metodi d'uso
CA3021634A1 (en) 2016-04-15 2017-10-19 Zymeworks Inc. Multi-specific antigen-binding constructs targeting immunotherapeutics
WO2017193046A1 (en) 2016-05-06 2017-11-09 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
ES2884071T3 (es) 2016-07-07 2021-12-10 Sage Therapeutics Inc 24-hidroxiesteroles sustituidos en 11 para el tratamiento de afecciones relacionadas con NMDA
CA3038984A1 (en) 2016-09-30 2018-04-05 Schlumberger Canada Limited Fiber measurements for fluid treatment processes in a well
RU2019115113A (ru) 2016-10-18 2020-11-24 Сейдж Терапьютикс, Инк. Оксистеролы и способы их применения
TW202523658A (zh) 2019-05-24 2025-06-16 美商賽吉醫療公司 化合物、組合物及使用方法
WO2022115620A1 (en) 2020-11-25 2022-06-02 Sage Therapeutics, Inc. 4-fluoro-(4-(4-benzyl)piperidin-1-yl)(2-(pyrimidin-4-yl)pyridin-3-yl)methanone derivatives and similar compounds as cyp46a1 inhibitors for the treatment of neurodegenerative disorders

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