JP2024520396A5 - - Google Patents
Info
- Publication number
- JP2024520396A5 JP2024520396A5 JP2023572623A JP2023572623A JP2024520396A5 JP 2024520396 A5 JP2024520396 A5 JP 2024520396A5 JP 2023572623 A JP2023572623 A JP 2023572623A JP 2023572623 A JP2023572623 A JP 2023572623A JP 2024520396 A5 JP2024520396 A5 JP 2024520396A5
- Authority
- JP
- Japan
- Prior art keywords
- alkylene
- alkyl
- cycloalkyl
- aryl
- membered
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163193256P | 2021-05-26 | 2021-05-26 | |
| US63/193,256 | 2021-05-26 | ||
| PCT/US2022/030841 WO2022251304A1 (en) | 2021-05-26 | 2022-05-25 | Substituted carbamate macrocyclic compounds and related methods of treatment |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2024520396A JP2024520396A (ja) | 2024-05-24 |
| JP2024520396A5 true JP2024520396A5 (https=) | 2025-03-24 |
| JP7833486B2 JP7833486B2 (ja) | 2026-03-19 |
Family
ID=82156598
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023572623A Active JP7833486B2 (ja) | 2021-05-26 | 2022-05-25 | 置換されるカルバメート大環状化合物および関連のある治療方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20240174689A1 (https=) |
| EP (1) | EP4347604B1 (https=) |
| JP (1) | JP7833486B2 (https=) |
| CN (1) | CN117651703A (https=) |
| AU (1) | AU2022280804A1 (https=) |
| CA (1) | CA3219490A1 (https=) |
| ES (1) | ES3057101T3 (https=) |
| WO (1) | WO2022251304A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20250155550A (ko) | 2023-03-16 | 2025-10-30 | 다케다 야쿠힌 고교 가부시키가이샤 | 매크로시클릭 헤테로시클 화합물 및 이의 용도 |
| WO2025124698A1 (en) | 2023-12-12 | 2025-06-19 | Idorsia Pharmaceuticals Ltd | Aryl sulfone and sulfanone derivatives as orexin receptor modulators |
| TW202542165A (zh) | 2023-12-19 | 2025-11-01 | 瑞士商愛杜西亞製藥有限公司 | 大環食慾素激動劑 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8258163B2 (en) | 2008-06-04 | 2012-09-04 | Board Of Regents, The University Of Texas System | Small-molecule agonists for type-2 orexin receptor |
| WO2014198880A1 (en) | 2013-06-14 | 2014-12-18 | Ferrer Internacional, S.A. | 2-(2-aminophenoxy)-3-chloronaphthalene-1,4-dione compounds having orexin 2 receptor agonist activity |
| US20160250224A1 (en) | 2013-09-24 | 2016-09-01 | The Board Of Regents Of The University Of Texas System | Orexin-control of bone formation and loss |
| CA2930693A1 (en) | 2013-11-15 | 2015-05-21 | The Board Of Trustees Of The Leland Stanford Junior Unversity | Methods of treating heart failure with agonists of hypocretin receptor 2 |
| PE20161064A1 (es) | 2013-12-12 | 2016-10-28 | Univ Tsukuba | Derivado de sulfonamida o sales de adicion de acido farmaceuticamente aceptables del mismo |
| WO2015147240A1 (ja) | 2014-03-28 | 2015-10-01 | 国立大学法人筑波大学 | 敗血症の予防治療剤 |
| PL3411358T3 (pl) | 2016-02-04 | 2022-02-28 | Takeda Pharmaceutical Company Limited | Podstawiony związek piperydynowy i jego zastosowanie |
| US11319286B2 (en) | 2017-08-03 | 2022-05-03 | Takeda Pharmaceutical Company Limited | Heterocyclic compound and application thereof |
| US20200207734A1 (en) * | 2017-08-03 | 2020-07-02 | Takeda Pharmaceutical Company Limited | Heterocyclic compound and use thereof |
| WO2020167701A1 (en) * | 2019-02-13 | 2020-08-20 | Merck Sharp & Dohme Corp. | Pyrrolidine orexin receptor agonists |
| FI4065585T3 (fi) | 2019-11-25 | 2025-09-26 | Alkermes Inc | Substituoituja makrosyklisiä yhdisteitä ja niihin liittyviä hoitomenetelmiä |
| WO2022051583A1 (en) * | 2020-09-03 | 2022-03-10 | Orexia Therapeutics Limited | Medium- or macro-cyclic benzyl-substituted heterocycle derivatives and their uses as orexin-2 receptor agonists |
| US12006330B2 (en) * | 2020-12-21 | 2024-06-11 | Alkermes, Inc. | Substituted macrocyclic compounds and related methods of treatment |
| US11760747B2 (en) * | 2020-12-21 | 2023-09-19 | Alkermes, Inc. | Substituted piperidino compounds and related methods of treatment |
-
2022
- 2022-05-25 WO PCT/US2022/030841 patent/WO2022251304A1/en not_active Ceased
- 2022-05-25 CN CN202280047652.3A patent/CN117651703A/zh active Pending
- 2022-05-25 ES ES22732772T patent/ES3057101T3/es active Active
- 2022-05-25 CA CA3219490A patent/CA3219490A1/en active Pending
- 2022-05-25 AU AU2022280804A patent/AU2022280804A1/en active Pending
- 2022-05-25 EP EP22732772.3A patent/EP4347604B1/en active Active
- 2022-05-25 JP JP2023572623A patent/JP7833486B2/ja active Active
-
2023
- 2023-11-14 US US18/389,467 patent/US20240174689A1/en active Pending
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