JP2024517671A5 - - Google Patents
Info
- Publication number
- JP2024517671A5 JP2024517671A5 JP2023565204A JP2023565204A JP2024517671A5 JP 2024517671 A5 JP2024517671 A5 JP 2024517671A5 JP 2023565204 A JP2023565204 A JP 2023565204A JP 2023565204 A JP2023565204 A JP 2023565204A JP 2024517671 A5 JP2024517671 A5 JP 2024517671A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- acid residue
- region
- polypeptide complex
- pair
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNPCT/CN2021/089400 | 2021-04-23 | ||
| CN2021089400 | 2021-04-23 | ||
| PCT/CN2022/088386 WO2022223016A1 (en) | 2021-04-23 | 2022-04-22 | Heterodimeric antibodies and antigen-binding fragment thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024517671A JP2024517671A (ja) | 2024-04-23 |
| JP2024517671A5 true JP2024517671A5 (https=) | 2025-05-01 |
Family
ID=83721948
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023565204A Pending JP2024517671A (ja) | 2021-04-23 | 2022-04-22 | ヘテロ二量体抗体およびその抗原結合断片 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20240182576A1 (https=) |
| EP (1) | EP4326772A4 (https=) |
| JP (1) | JP2024517671A (https=) |
| CN (1) | CN117597361A (https=) |
| AU (1) | AU2022261269A1 (https=) |
| CA (1) | CA3217487A1 (https=) |
| WO (1) | WO2022223016A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW202506741A (zh) * | 2023-04-06 | 2025-02-16 | 美商麥迪紐有限責任公司 | 工程化抗體 |
| WO2025103355A1 (zh) * | 2023-11-14 | 2025-05-22 | 信达生物制药(苏州)有限公司 | 抗egfr和her3双特异性抗体-药物偶联物及其用途 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RS60499B1 (sr) * | 2011-12-20 | 2020-08-31 | Medimmune Llc | Modifikovani polipeptidi za bispecifične skelete antitela |
| UY35148A (es) * | 2012-11-21 | 2014-05-30 | Amgen Inc | Immunoglobulinas heterodiméricas |
| US10118971B2 (en) * | 2013-03-13 | 2018-11-06 | Ibentrus, Inc. | Protein in which electrical interaction is introduced within hydrophobic interaction site and preparation method therefor |
| ES2936810T3 (es) * | 2014-05-16 | 2023-03-22 | Pfizer | Anticuerpos biespecíficos con interfaces CH1-CL de ingeniería |
| WO2016172485A2 (en) * | 2015-04-24 | 2016-10-27 | Genentech, Inc. | Multispecific antigen-binding proteins |
| KR102669686B1 (ko) * | 2015-04-28 | 2024-05-29 | 자임워크스 비씨 인코포레이티드 | 변형된 항원 결합 폴리펩티드 작제물 및 이의 용도 |
| CA2998174A1 (en) * | 2015-09-15 | 2017-03-23 | Amgen Inc. | Tetravalent bispecific and tetraspecific antigen binding proteins and uses thereof |
| CR20180365A (es) * | 2015-12-16 | 2018-09-28 | Amgen Inc | PROTEÍNAS DE UNIÓN AL ANTÍGENO BISPECÍFICO DE ANTI-TL1A/ANTI-TNF-a Y SUS USOS |
| CN109475627B (zh) * | 2016-05-26 | 2023-01-06 | 齐鲁普吉湾生物治疗公司 | 抗体混合物 |
| MX2019005552A (es) * | 2016-11-14 | 2019-08-12 | Amgen Inc | Proteinas de union a antigenos biespecificas o biparatopicas y usos de las mismas. |
| CN110357960A (zh) * | 2018-04-10 | 2019-10-22 | 广州爱思迈生物医药科技有限公司 | 抗体及抗体改造方法 |
| WO2020028269A2 (en) * | 2018-07-30 | 2020-02-06 | Invenra Inc. | Multispecific treg binding molecules |
| AU2019412561A1 (en) * | 2018-12-24 | 2021-08-12 | Sanofi | Multispecific binding proteins with mutant Fab domains |
| CN111484555B (zh) * | 2019-01-28 | 2022-07-08 | 正大天晴药业集团股份有限公司 | 新型双特异性cd3/cd20多肽复合物 |
| JP7500619B2 (ja) * | 2019-05-30 | 2024-06-17 | アムジエン・インコーポレーテツド | 抗体の二量体化を促進するためのヒンジ領域の操作 |
-
2022
- 2022-04-22 CA CA3217487A patent/CA3217487A1/en active Pending
- 2022-04-22 EP EP22791122.9A patent/EP4326772A4/en active Pending
- 2022-04-22 AU AU2022261269A patent/AU2022261269A1/en active Pending
- 2022-04-22 US US18/556,665 patent/US20240182576A1/en active Pending
- 2022-04-22 WO PCT/CN2022/088386 patent/WO2022223016A1/en not_active Ceased
- 2022-04-22 CN CN202280030146.3A patent/CN117597361A/zh active Pending
- 2022-04-22 JP JP2023565204A patent/JP2024517671A/ja active Pending
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