JP2024517027A - キメラ抗原受容体及びそれを含む改変細胞 - Google Patents

キメラ抗原受容体及びそれを含む改変細胞 Download PDF

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JP2024517027A
JP2024517027A JP2023569935A JP2023569935A JP2024517027A JP 2024517027 A JP2024517027 A JP 2024517027A JP 2023569935 A JP2023569935 A JP 2023569935A JP 2023569935 A JP2023569935 A JP 2023569935A JP 2024517027 A JP2024517027 A JP 2024517027A
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seq
amino acid
acid sequence
chain variable
complementarity determining
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アルバーニ，サルヴァトーレ
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Singapore Health Services Pte Ltd
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    • A—HUMAN NECESSITIES
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K40/00—Cellular immunotherapy
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JP2023569935A 2021-05-11 2022-05-11 キメラ抗原受容体及びそれを含む改変細胞 Pending JP2024517027A (ja)

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SG10202104940X 2021-05-11
SG10202104940X 2021-05-11
PCT/SG2022/050308 WO2022240360A1 (en) 2021-05-11 2022-05-11 Chimeric antigen receptors and modified cells comprising the same

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JP2024517027A true JP2024517027A (ja) 2024-04-18
JP2024517027A5 JP2024517027A5 (https=) 2025-05-19

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US (1) US20240252536A1 (https=)
EP (1) EP4337684A4 (https=)
JP (1) JP2024517027A (https=)
KR (1) KR20240007204A (https=)
CN (1) CN117616039A (https=)
AU (1) AU2022271707A1 (https=)
CA (1) CA3215528A1 (https=)
MX (1) MX2023013296A (https=)
WO (1) WO2022240360A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3186753A1 (en) 2020-07-20 2022-01-27 John Mumm Dual cytokine fusion proteins comprising il-10
CA3244604A1 (en) 2022-02-22 2023-08-31 Deka Biosciences, Inc. METHOD FOR REDUCING A BISPECIFIC T LYMPHOCYTE RECRUITER OR A CHIMERICAL ANTIGEN RECEPTOR T LYMPHOCYTE CYTOKINE RELEASE SYNDROME USING INTERLEUKIN 4 OR 10, OR AN ASSOCIATED FUSION PROTEIN
WO2024128219A1 (ja) * 2022-12-13 2024-06-20 愛知県 キメラ抗原受容体
CN116874596B (zh) * 2023-09-06 2023-11-24 南京佰抗生物科技有限公司 抗S100β蛋白的单克隆抗体及其制备方法和应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019193476A1 (en) * 2018-04-02 2019-10-10 National University Of Singapore Neutralization of human cytokines with membrane-bound anti-cytokine non-signaling binders expressed in immune cells
KR20190143070A (ko) * 2018-06-20 2019-12-30 인하대학교 산학협력단 항 TNF/IFN scFv-Fc 이중 표적 항체 및 이의 이용

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Publication number Priority date Publication date Assignee Title
WO2018057585A1 (en) * 2016-09-21 2018-03-29 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Chimeric antigen receptor (car) that targets chemokine receptor ccr4 and its use
US11788093B2 (en) * 2017-09-07 2023-10-17 University Of Florida Research Foundation, Inc. Chimeric antigen receptor t-cells expressing interleukin-8 receptor
JP7296133B2 (ja) * 2018-03-16 2023-06-22 国立大学法人信州大学 遺伝子改変細胞及びその作製方法
EP3781176A4 (en) * 2018-04-09 2022-05-25 The Trustees of the University of Pennsylvania METHODS AND COMPOSITIONS USING A VIRAL VECTOR FOR THE EXPRESSION OF A TRANSGENE AND AN EFFECTOR
IL317193A (en) * 2022-05-24 2025-01-01 Leibniz Inst F?R Immuntherapie Lit Artificial immune system receptors
CN118005804A (zh) * 2024-01-29 2024-05-10 北京医院 一种响应致炎细胞因子的CAR序列和CAR-Treg细胞的构建方法及应用

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019193476A1 (en) * 2018-04-02 2019-10-10 National University Of Singapore Neutralization of human cytokines with membrane-bound anti-cytokine non-signaling binders expressed in immune cells
KR20190143070A (ko) * 2018-06-20 2019-12-30 인하대학교 산학협력단 항 TNF/IFN scFv-Fc 이중 표적 항체 및 이의 이용

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WO2022240360A9 (en) 2022-12-08
AU2022271707A1 (en) 2023-11-09
CN117616039A (zh) 2024-02-27
CA3215528A1 (en) 2022-11-17
EP4337684A4 (en) 2025-08-20
US20240252536A1 (en) 2024-08-01
AU2022271707A9 (en) 2023-11-16
MX2023013296A (es) 2023-12-04
EP4337684A1 (en) 2024-03-20
KR20240007204A (ko) 2024-01-16
WO2022240360A1 (en) 2022-11-17

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