JP2024516996A5 - - Google Patents

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Publication number
JP2024516996A5
JP2024516996A5 JP2023567910A JP2023567910A JP2024516996A5 JP 2024516996 A5 JP2024516996 A5 JP 2024516996A5 JP 2023567910 A JP2023567910 A JP 2023567910A JP 2023567910 A JP2023567910 A JP 2023567910A JP 2024516996 A5 JP2024516996 A5 JP 2024516996A5
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JP
Japan
Application number
JP2023567910A
Other languages
Japanese (ja)
Other versions
JPWO2022235759A5 (https=
JP2024516996A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/027622 external-priority patent/WO2022235759A1/en
Publication of JP2024516996A publication Critical patent/JP2024516996A/ja
Publication of JPWO2022235759A5 publication Critical patent/JPWO2022235759A5/ja
Publication of JP2024516996A5 publication Critical patent/JP2024516996A5/ja
Pending legal-status Critical Current

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JP2023567910A 2021-05-05 2022-05-04 トランスジェニック哺乳動物およびその使用方法 Pending JP2024516996A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163184440P 2021-05-05 2021-05-05
US63/184,440 2021-05-05
PCT/US2022/027622 WO2022235759A1 (en) 2021-05-05 2022-05-04 Transgenic rodents expressing chimeric equine-rodent antibodies and methods of use thereof

Publications (3)

Publication Number Publication Date
JP2024516996A JP2024516996A (ja) 2024-04-18
JPWO2022235759A5 JPWO2022235759A5 (https=) 2025-05-14
JP2024516996A5 true JP2024516996A5 (https=) 2025-05-14

Family

ID=81750504

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023567910A Pending JP2024516996A (ja) 2021-05-05 2022-05-04 トランスジェニック哺乳動物およびその使用方法

Country Status (9)

Country Link
US (1) US20240215556A1 (https=)
EP (1) EP4333613A1 (https=)
JP (1) JP2024516996A (https=)
KR (1) KR20240004503A (https=)
CN (1) CN117440753A (https=)
AU (1) AU2022268937A1 (https=)
CA (1) CA3216988A1 (https=)
IL (1) IL307638A (https=)
WO (1) WO2022235759A1 (https=)

Family Cites Families (32)

* Cited by examiner, † Cited by third party
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CA1293460C (en) 1985-10-07 1991-12-24 Brian Lee Sauer Site-specific recombination of dna in yeast
GB8823869D0 (en) 1988-10-12 1988-11-16 Medical Res Council Production of antibodies
US5175384A (en) 1988-12-05 1992-12-29 Genpharm International Transgenic mice depleted in mature t-cells and methods for making transgenic mice
GB8904009D0 (en) 1989-02-22 1989-04-05 Celltech Ltd Vector
US5464764A (en) 1989-08-22 1995-11-07 University Of Utah Research Foundation Positive-negative selection methods and vectors
US6689610B1 (en) 1989-08-22 2004-02-10 University Of Utah Research Foundation Cells and non-human organisms containing predetermined genomic modifications and positive-negative selection methods and vectors for making same
US6673986B1 (en) 1990-01-12 2004-01-06 Abgenix, Inc. Generation of xenogeneic antibodies
US5814318A (en) 1990-08-29 1998-09-29 Genpharm International Inc. Transgenic non-human animals for producing heterologous antibodies
US7041871B1 (en) 1995-10-10 2006-05-09 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
ATE352612T1 (de) 1990-08-29 2007-02-15 Pharming Intellectual Pty Bv Homologe rekombination in säugetier-zellen
US5789650A (en) 1990-08-29 1998-08-04 Genpharm International, Inc. Transgenic non-human animals for producing heterologous antibodies
US5661016A (en) 1990-08-29 1997-08-26 Genpharm International Inc. Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
US5877397A (en) 1990-08-29 1999-03-02 Genpharm International Inc. Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
US5874299A (en) 1990-08-29 1999-02-23 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
WO1992015694A1 (en) 1991-03-08 1992-09-17 The Salk Institute For Biological Studies Flp-mediated gene modification in mammalian cells, and compositions and cells useful therefor
DE4228162C1 (de) 1992-08-25 1994-01-13 Rajewsky Klaus Dr Verfahren zum Ersetzen homologer Genabschnitte aus Säugern in der Keimbahn von nicht-menschlichen Säugern
US5593598A (en) 1994-04-20 1997-01-14 Mcginness; Michael P. Method and apparatus for closed loop recycling of contaminated cleaning solution
US6091001A (en) 1995-03-29 2000-07-18 Abgenix, Inc. Production of antibodies using Cre-mediated site-specific recombination
US6130364A (en) 1995-03-29 2000-10-10 Abgenix, Inc. Production of antibodies using Cre-mediated site-specific recombination
EP1500329B1 (en) 1996-12-03 2012-03-21 Amgen Fremont Inc. Human antibodies that specifically bind human TNF alpha
US6774279B2 (en) 1997-05-30 2004-08-10 Carnegie Institution Of Washington Use of FLP recombinase in mice
FR2814642B1 (fr) 2000-10-03 2005-07-01 Ass Pour Le Dev De La Rech En Souris transgenique pour la recombinaison ciblee mediee par la cre-er modifiee
US6596541B2 (en) 2000-10-31 2003-07-22 Regeneron Pharmaceuticals, Inc. Methods of modifying eukaryotic cells
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ATE536374T1 (de) * 2006-09-01 2011-12-15 Therapeutic Human Polyclonals Inc Erhöhte expression von humanem oder humanisiertem immunglobulin bei nicht-humanen transgenen tieren
JP6482757B2 (ja) * 2010-07-26 2019-03-13 トリアンニ インコーポレイテッドTrianni,Inc. トランスジェニック動物および使用方法
GB2528811A (en) * 2011-05-06 2016-02-03 Nvip Pty Ltd Anti-nerve growth factor antibodies and methods of preparing and using the same
US20170058052A1 (en) 2015-08-24 2017-03-02 Trianni, Inc. Enhanced production of immunoglobulins
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WO2021003152A1 (en) * 2019-07-01 2021-01-07 Trianni, Inc. Transgenic mammals and methods of use thereof

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