JPWO2023090361A5 - - Google Patents

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Publication number
JPWO2023090361A5
JPWO2023090361A5 JP2023562377A JP2023562377A JPWO2023090361A5 JP WO2023090361 A5 JPWO2023090361 A5 JP WO2023090361A5 JP 2023562377 A JP2023562377 A JP 2023562377A JP 2023562377 A JP2023562377 A JP 2023562377A JP WO2023090361 A5 JPWO2023090361 A5 JP WO2023090361A5
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JP
Japan
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region
sequence
heavy chain
immunoglobulin heavy
human
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JP2023562377A
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English (en)
Japanese (ja)
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JPWO2023090361A1 (https=
JP7748680B2 (ja
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Priority claimed from PCT/JP2022/042560 external-priority patent/WO2023090361A1/ja
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JP2023562377A 2021-11-16 2022-11-16 改変ｄ領域を含むヒト免疫グロブリン重鎖遺伝子座を有する哺乳動物人工染色体ベクター、及びそのベクターを保持する細胞又は非ヒト動物 Active JP7748680B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2021186124 2021-11-16
JP2021186124 2021-11-16
PCT/JP2022/042560 WO2023090361A1 (ja) 2021-11-16 2022-11-16 改変ｄ領域を含むヒト免疫グロブリン重鎖遺伝子座を有する哺乳動物人工染色体ベクター、及びそのベクターを保持する細胞又は非ヒト動物

Publications (3)

Publication Number Publication Date
JPWO2023090361A1 JPWO2023090361A1 (https=) 2023-05-25
JPWO2023090361A5 true JPWO2023090361A5 (https=) 2024-05-23
JP7748680B2 JP7748680B2 (ja) 2025-10-03

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ID=86397075

Family Applications (1)

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JP2023562377A Active JP7748680B2 (ja) 2021-11-16 2022-11-16 改変ｄ領域を含むヒト免疫グロブリン重鎖遺伝子座を有する哺乳動物人工染色体ベクター、及びそのベクターを保持する細胞又は非ヒト動物

Country Status (4)

Country Link
US (1) US20240392313A1 (https=)
EP (1) EP4389895A4 (https=)
JP (1) JP7748680B2 (https=)
WO (1) WO2023090361A1 (https=)

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0585287T3 (da) 1990-07-10 2000-04-17 Cambridge Antibody Tech Fremgangsmåde til fremstilling af specifikke bindingsparelementer
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
EP0605522B1 (en) 1991-09-23 1999-06-23 Medical Research Council Methods for the production of humanized antibodies
PT1024191E (pt) 1991-12-02 2008-12-22 Medical Res Council Produção de auto-anticorpos a partir de reportórios de segmentos de anticorpo e exibidos em fagos
CA2131151A1 (en) 1992-03-24 1994-09-30 Kevin S. Johnson Methods for producing members of specific binding pairs
GB9313509D0 (en) 1993-06-30 1993-08-11 Medical Res Council Chemisynthetic libraries
WO1995015388A1 (en) 1993-12-03 1995-06-08 Medical Research Council Recombinant binding proteins and peptides
KR100308764B1 (ko) 1995-08-29 2001-12-17 마나배게이사꾸 키메라동물및그의제작법
ATE455179T1 (de) 1997-02-28 2010-01-15 Kyowa Hakko Kirin Co Ltd Humanes chromosomfragment und ein vektor, der dies enthält
TWI255853B (en) 1998-08-21 2006-06-01 Kirin Brewery Method for modifying chromosomes
US8048999B2 (en) 2005-12-13 2011-11-01 Kyoto University Nuclear reprogramming factor
JP5588866B2 (ja) * 2007-08-10 2014-09-10 メダレックス エル．エル．シー． Ｈｃｏ３２およびｈｃｏ２７、ならびに関連実施例
ES2984483T3 (es) * 2010-03-31 2024-10-29 Ablexis Llc Ingeniería genética de ratones para la producción de anticuerpos quiméricos
US10793829B2 (en) * 2010-07-26 2020-10-06 Trianni, Inc. Transgenic mammals and methods of use thereof
CN103025884B (zh) * 2010-07-26 2015-11-25 特里安尼公司 转基因动物和使用方法
BR112014006394A2 (pt) * 2011-09-19 2017-03-28 Kymab Ltd manipulação de diversidade genética de imunoglobulina e terapêuticos multi-anticorpos
EP3533867A4 (en) 2016-10-31 2020-07-22 National University Corporation Tottori University NON-HUMAN ANIMAL PRODUCING HUMAN ANTIBODIES AND PROCESS FOR THE PREPARATION OF HUMAN ANTIBODIES USING IT
CN112352054A (zh) 2018-03-16 2021-02-09 国立大学法人鸟取大学 小鼠人工染色体载体及其用途
DK3993623T3 (da) * 2019-07-01 2025-05-26 Zoetis Services Llc Transgene gnavere og fremgangsmåder til anvendelse deraf
JP7235005B2 (ja) 2020-05-27 2023-03-08 株式会社三洋物産 遊技機

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