JP2024516677A - 敗血症の早期検出用のｎｇａｌマーカーパネル - Google Patents

敗血症の早期検出用のｎｇａｌマーカーパネル Download PDF

Info

Publication number
JP2024516677A
JP2024516677A JP2023566800A JP2023566800A JP2024516677A JP 2024516677 A JP2024516677 A JP 2024516677A JP 2023566800 A JP2023566800 A JP 2023566800A JP 2023566800 A JP2023566800 A JP 2023566800A JP 2024516677 A JP2024516677 A JP 2024516677A
Authority
JP
Japan
Prior art keywords
biomarker
subject
amount
bnp
assessing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023566800A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024516677A5 (https=
Inventor
グリューネバルト，フェリックス
イェーガー，ヴィクトル・ヨハン・ラウル
クラマー，マルティン
シュッツ，フィリップ
ホルタイ，マリア フォン
ヴェーバー，シュテフェン
ベクマイヤー，ハイケ
ビーンヒューズ－テレン，ウルスラ－ヘンリケ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of JP2024516677A publication Critical patent/JP2024516677A/ja
Publication of JP2024516677A5 publication Critical patent/JP2024516677A5/ja
Pending legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/26—Infectious diseases, e.g. generalised sepsis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/50—Determining the risk of developing a disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Databases & Information Systems (AREA)
  • Data Mining & Analysis (AREA)
  • Epidemiology (AREA)
  • Primary Health Care (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2023566800A 2021-04-30 2022-04-29 敗血症の早期検出用のｎｇａｌマーカーパネル Pending JP2024516677A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP21171494 2021-04-30
EP21171494.4 2021-04-30
PCT/EP2022/061577 WO2022229435A2 (en) 2021-04-30 2022-04-29 Ngal marker panels for early detection of sepsis

Publications (2)

Publication Number Publication Date
JP2024516677A true JP2024516677A (ja) 2024-04-16
JP2024516677A5 JP2024516677A5 (https=) 2025-04-24

Family

ID=75746436

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023566800A Pending JP2024516677A (ja) 2021-04-30 2022-04-29 敗血症の早期検出用のｎｇａｌマーカーパネル

Country Status (5)

Country Link
US (1) US20240248098A1 (https=)
EP (1) EP4330685A2 (https=)
JP (1) JP2024516677A (https=)
CN (1) CN117295950A (https=)
WO (1) WO2022229435A2 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119534855A (zh) * 2024-11-08 2025-02-28 山西康健恩生物科技有限公司 一种用于末梢血的肝素结合蛋白测定试剂盒

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008501979A (ja) * 2004-06-07 2008-01-24 チルドレンズ　ホスピタル　メディカル　センター 腎疾患および腎損傷の早期発見のための方法
JP2009510478A (ja) * 2005-10-03 2009-03-12 バイオサイト インコーポレイテッド 全身性炎症反応症候群の診断および／または予後診断のための方法および組成物
JP2010509596A (ja) * 2006-11-09 2010-03-25 プロテオジェニックス， インコーポレイテッド 妊娠中の雌における子宮内感染の検出または早産のリスクの決定のための子宮頸部液のプロテオーム解析
JP2010529468A (ja) * 2007-06-12 2010-08-26 ハンサ メディカル アクチボラゲット 診断方法
JP2012159356A (ja) * 2011-01-31 2012-08-23 Mochida Pharmaceut Co Ltd 敗血症診断用組合せマーカー
US20150011412A1 (en) * 2012-01-24 2015-01-08 Cd Diagnostics, Inc. System for detecting infection in synovial fluid

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2476597C (en) 2002-02-28 2011-05-17 Metanomics Gmbh & Co. Kgaa Mass spectrometry method for analysing mixtures of substances
US20090197794A1 (en) 2005-07-13 2009-08-06 Aird William C Methods of Diagnosing and Treating an Inflammatory Response
CN103123359B (zh) 2007-08-03 2015-07-29 B.R.A.H.M.S有限公司 降钙素原(pct)在患原发性非传染疾病的患者的风险分级和预后中的应用
RU2016112915A (ru) 2013-09-05 2017-10-09 Эф-Ай-Оу Корпорейшн Биомаркеры для раннего выявления критической или угрожающей жизни ответной реакции на заболевание и/или ответной реакции на лечение

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008501979A (ja) * 2004-06-07 2008-01-24 チルドレンズ　ホスピタル　メディカル　センター 腎疾患および腎損傷の早期発見のための方法
JP2009510478A (ja) * 2005-10-03 2009-03-12 バイオサイト インコーポレイテッド 全身性炎症反応症候群の診断および／または予後診断のための方法および組成物
JP2010509596A (ja) * 2006-11-09 2010-03-25 プロテオジェニックス， インコーポレイテッド 妊娠中の雌における子宮内感染の検出または早産のリスクの決定のための子宮頸部液のプロテオーム解析
JP2010529468A (ja) * 2007-06-12 2010-08-26 ハンサ メディカル アクチボラゲット 診断方法
JP2012159356A (ja) * 2011-01-31 2012-08-23 Mochida Pharmaceut Co Ltd 敗血症診断用組合せマーカー
US20150011412A1 (en) * 2012-01-24 2015-01-08 Cd Diagnostics, Inc. System for detecting infection in synovial fluid

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
JAYSHIL J. PATEL ET AL.: "The Association of Serum Bilirubin Levels on the Outcomes of Severe Sepsis", JOURNAL OF INTENSIVE CARE MEDICINE, vol. 30(1), JPN7026000994, 2015, pages 23 - 29, ISSN: 0005811723 *
M. MARTIN-FERNANDEZ ET AL.: "Endothelial dysfunction is an early indicator of sepsis and neutrophil degranulation of septic shock", BJS OPEN, vol. 4(3), JPN7026000995, 2020, pages 524 - 534, ISSN: 0005811724 *
MARIA BERGQUIST ET AL.: "TNFR1, TNFR2, neutrophil gelatinase-associated lipocalin and heparin binding protein in identifying", SCIENTIFIC REPORTS, vol. 10(1), JPN6026009281, 2020, pages 15350, ISSN: 0005811721 *
RONI LEHMANN-WERMAN ET AL.: "Monitoring liver damage using hepatocyte-specific methylation markers in cell-free circulating DNA", JCI INSIGHT, vol. 3(12), JPN7026000993, 2018, pages 120687, ISSN: 0005811722 *

Also Published As

Publication number Publication date
WO2022229435A2 (en) 2022-11-03
EP4330685A2 (en) 2024-03-06
CN117295950A (zh) 2023-12-26
WO2022229435A3 (en) 2022-12-15
US20240248098A1 (en) 2024-07-25

Similar Documents

Publication Publication Date Title
JP2026048754A (ja) 敗血症の早期検出用のｐｃｔマーカーパネル
JP2024516677A (ja) 敗血症の早期検出用のｎｇａｌマーカーパネル
JP2024516680A (ja) 敗血症の早期検出用のｉｌ６マーカーパネル
JP2024516678A (ja) 敗血症の早期検出用のｓｔｒｅｍ１マーカーパネル
JP2024516679A (ja) 敗血症の早期検出用のｉｇｆｂｐ７マーカーパネル
JP2024516001A (ja) 敗血症の早期検出のためのｅｓｍ１マーカーパネル
JP2024537774A (ja) 敗血症の早期検出のためのＭＲ－ｐｒｏＡＤＭマーカーパネル
JP2024515086A (ja) 敗血症の早期検出のためのｇｄｆ１５マーカーパネル
US20240230672A1 (en) Presepsin marker panels for early detection of sepsis
JP2024516681A (ja) 敗血症の早期検出のためのｓＦｌｔ１マーカーパネル
JP2025506704A (ja) 敗血症を早期検出するためのｄｌｌ１マーカーパネル

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20250416

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20250416

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20260227

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20260309