JP2024515936A5 - - Google Patents

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Publication number
JP2024515936A5
JP2024515936A5 JP2023556950A JP2023556950A JP2024515936A5 JP 2024515936 A5 JP2024515936 A5 JP 2024515936A5 JP 2023556950 A JP2023556950 A JP 2023556950A JP 2023556950 A JP2023556950 A JP 2023556950A JP 2024515936 A5 JP2024515936 A5 JP 2024515936A5
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JP
Japan
Prior art keywords
ribonucleic acid
guide
sequence
manipulated
class
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JP2023556950A
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English (en)
Japanese (ja)
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JP7877351B2 (ja
JP2024515936A (ja
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Priority claimed from PCT/US2022/021004 external-priority patent/WO2022198080A1/en
Publication of JP2024515936A publication Critical patent/JP2024515936A/ja
Publication of JP2024515936A5 publication Critical patent/JP2024515936A5/ja
Application granted granted Critical
Publication of JP7877351B2 publication Critical patent/JP7877351B2/ja
Active legal-status Critical Current
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JP2023556950A 2021-03-19 2022-03-18 Cas酵素を用いたマルチプレックス編集 Active JP7877351B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202163163510P 2021-03-19 2021-03-19
US63/163,510 2021-03-19
US202163186506P 2021-05-10 2021-05-10
US63/186,506 2021-05-10
US202163241916P 2021-09-08 2021-09-08
US63/241,916 2021-09-08
PCT/US2022/021004 WO2022198080A1 (en) 2021-03-19 2022-03-18 Multiplex editing with cas enzymes

Publications (3)

Publication Number Publication Date
JP2024515936A JP2024515936A (ja) 2024-04-11
JP2024515936A5 true JP2024515936A5 (enExample) 2025-03-25
JP7877351B2 JP7877351B2 (ja) 2026-06-22

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023556950A Active JP7877351B2 (ja) 2021-03-19 2022-03-18 Cas酵素を用いたマルチプレックス編集

Country Status (9)

Country Link
US (1) US20250075233A1 (enExample)
EP (1) EP4308699A4 (enExample)
JP (1) JP7877351B2 (enExample)
KR (1) KR20230157387A (enExample)
AU (1) AU2022237663A1 (enExample)
BR (1) BR112023018948A2 (enExample)
CA (1) CA3210361A1 (enExample)
MX (1) MX2023010969A (enExample)
WO (1) WO2022198080A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021178933A2 (en) 2020-03-06 2021-09-10 Metagenomi Ip Technologies, Llc Class ii, type v crispr systems
US10913941B2 (en) 2019-02-14 2021-02-09 Metagenomi Ip Technologies, Llc Enzymes with RuvC domains
CN116096892A (zh) * 2020-05-08 2023-05-09 宏基因组学公司 具有RuvC结构域的酶
KR20230134543A (ko) * 2021-01-22 2023-09-21 메타지노미, 인크. 신규한 조작된 뉴클레아제 및 키메라 뉴클레아제
CN119452085A (zh) 2021-08-27 2025-02-14 宏基因组学公司 具有ruvc结构域的酶
KR20240110603A (ko) 2021-11-24 2024-07-15 메타지노미, 인크. 엔도뉴클레아제 시스템
WO2024127370A1 (en) * 2022-12-16 2024-06-20 LifeEDIT Therapeutics, Inc. Guide rnas that target trac gene and methods of use

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003233634A1 (en) 2002-05-20 2003-12-12 Pharmacia Corporation Antisense modulation of glucocorticoid receptor expression
US20150017136A1 (en) 2013-07-15 2015-01-15 Cellectis Methods for engineering allogeneic and highly active t cell for immunotherapy
JP6608807B2 (ja) * 2013-05-29 2019-11-20 セレクティス Rnaガイドcasヌクレアーゼ系を用いることによって免疫療法のためにt細胞を操作するための方法
AU2016262093B2 (en) 2015-05-13 2022-08-18 Seattle Children' S Hospital (Dba Seattle Children 's Research Institute) Enhancing endonuclease based gene editing in primary cells
MX2018010484A (es) 2016-03-04 2019-01-10 Editas Medicine Inc Métodos, composiciones y componentes relacionados con crispr-cpf1 para la inmunoterapia contra el cáncer.
BR112019023608A2 (pt) 2017-05-12 2020-05-26 Crispr Therapeutics Ag Materiais e métodos para células manipuladas e seus usos em imuno-oncologia
EP3686275A4 (en) 2017-09-18 2021-09-29 Edigene Inc. GENE EDITING LYMPHOCYTE T AND RELATED USE
US12359223B2 (en) * 2018-01-30 2025-07-15 Editas Medicine, Inc. Systems and methods for modulating chromosomal rearrangements
US12275951B2 (en) 2018-02-06 2025-04-15 Ohio State Innovation Foundation Engineered guide RNA and uses thereof
BR112020015488A2 (pt) 2018-02-08 2020-12-08 Sangamo Therapeutics, Inc. Nucleases alvo-específicas modificadas
KR20240007322A (ko) * 2019-02-14 2024-01-16 메타지노미, 인크. Ruvc 도메인이 존재하는 효소
US10913941B2 (en) * 2019-02-14 2021-02-09 Metagenomi Ip Technologies, Llc Enzymes with RuvC domains
EP3938510A1 (en) 2019-03-11 2022-01-19 Sorrento Therapeutics, Inc. Improved process for integration of dna constructs using rna-guided endonucleases
GB201907733D0 (en) * 2019-05-31 2019-07-17 Governing Council Of The Univ Of Toronto Methods and compositions for multiplex gene editing

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