JP2024511767A5 - - Google Patents

Info

Publication number
JP2024511767A5
JP2024511767A5 JP2023557719A JP2023557719A JP2024511767A5 JP 2024511767 A5 JP2024511767 A5 JP 2024511767A5 JP 2023557719 A JP2023557719 A JP 2023557719A JP 2023557719 A JP2023557719 A JP 2023557719A JP 2024511767 A5 JP2024511767 A5 JP 2024511767A5
Authority
JP
Japan
Prior art keywords
pharmaceutical composition
composition according
human subject
administered
dose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023557719A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024511767A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/022485 external-priority patent/WO2022212459A1/en
Publication of JP2024511767A publication Critical patent/JP2024511767A/ja
Publication of JP2024511767A5 publication Critical patent/JP2024511767A5/ja
Pending legal-status Critical Current

Links

JP2023557719A 2021-03-31 2022-03-30 筋萎縮性側索硬化症の治療 Pending JP2024511767A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163168972P 2021-03-31 2021-03-31
US63/168,972 2021-03-31
PCT/US2022/022485 WO2022212459A1 (en) 2021-03-31 2022-03-30 Treatment of amyotrophic lateral sclerosis

Publications (2)

Publication Number Publication Date
JP2024511767A JP2024511767A (ja) 2024-03-15
JP2024511767A5 true JP2024511767A5 (https=) 2025-04-08

Family

ID=81346346

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023557719A Pending JP2024511767A (ja) 2021-03-31 2022-03-30 筋萎縮性側索硬化症の治療

Country Status (11)

Country Link
US (1) US20240182903A1 (https=)
EP (1) EP4314294A1 (https=)
JP (1) JP2024511767A (https=)
KR (1) KR20230172502A (https=)
CN (1) CN117062911A (https=)
AU (1) AU2022252236A1 (https=)
BR (1) BR112023019877A2 (https=)
CA (1) CA3214585A1 (https=)
MX (1) MX2023011214A (https=)
TW (1) TW202304471A (https=)
WO (1) WO2022212459A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN120350010B (zh) * 2025-06-24 2025-09-09 羿美诚健(上海)生物医药有限公司 靶向PIKfyve基因的小核酸及其药物组合物和用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2452458A1 (en) 2001-07-03 2003-01-16 Isis Pharmaceuticals, Inc. Nuclease resistant chimeric oligonucleotides
HUE050704T2 (hu) 2014-04-01 2020-12-28 Biogen Ma Inc Összetételek a SOD-1 expressziójának modulálására
TWI906204B (zh) * 2018-12-14 2025-12-01 美商百健Ma公司 用於治療及預防肌肉萎縮性脊髓側索硬化症之組合物及方法

Similar Documents

Publication Publication Date Title
Xia et al. GLS1-mediated glutaminolysis unbridled by MALT1 protease promotes psoriasis pathogenesis
JP6608309B2 (ja) Cmt及び関連疾患の処置のための新規な治療的アプローチ
JP2022513721A5 (https=)
US11680266B2 (en) Endomucin inhibitor as an anti-angiogenic agent
JP7345466B2 (ja) アンチセンスオリゴヌクレオチドを含有する組成物およびデュシェンヌ型筋ジストロフィーの治療へのその使用
Tomar et al. Insight into the pivotal role of signaling pathways in psoriasis pathogenesis, potential therapeutic molecules and drug delivery approaches
JP7543278B2 (ja) 有機化合物
KR102821047B1 (ko) 근위축 측삭 경화증의 치료 및 방지를 위한 조성물 및 방법
KR20210008498A (ko) Fxi 발현을 감소시키기 위한 화합물 및 방법
TW201919655A (zh) 治療肌肉萎縮症的方法
Boujon et al. Dual PPARα/γ agonist aleglitazar confers stroke protection in a model of mild focal brain ischemia in mice
CN104955451A (zh) 恩他卡朋在预防或治疗肥胖等代谢综合征中的应用
US11660306B2 (en) Treatment of Rett syndrome
Cheng et al. Identification of a novel hybridization from isosorbide 5-mononitrate and bardoxolone methyl with dual activities of pulmonary vasodilation and vascular remodeling inhibition on pulmonary arterial hypertension rats
Sunilkumar et al. REDD1-dependent GSK3β dephosphorylation promotes NF-κB activation and macrophage infiltration in the retina of diabetic mice
WO2022271808A1 (en) Novel rna therapeutics and uses thereof
KR20220035137A (ko) Ppm1a 억제제 및 그의 사용 방법
JP2024511767A5 (https=)
US20200080155A1 (en) Dot1l inhibitors and uses thereof
Sayed et al. JAK1 rs310241 and JAK3 rs3008 genotypes may increase susceptibility to psoriasis: a case control study
US6214571B1 (en) Method for inhibiting adenylosuccinate synthetase activity in malignant methylthioadenosine phosphorylase deficient cells
JP2024511767A (ja) 筋萎縮性側索硬化症の治療
KR20220152569A (ko) 프리칼리크레인-연합된 병태를 치료하고 예방하는 조성물 및 방법
RU2824046C2 (ru) Составы для лечения и предотвращения бокового амиотрофического склероза
Li et al. Effects of anti-tuberculosis drugs on the proliferation and differentiation of alveolar stem cells