JP2024511463A5 - - Google Patents
Info
- Publication number
- JP2024511463A5 JP2024511463A5 JP2023558515A JP2023558515A JP2024511463A5 JP 2024511463 A5 JP2024511463 A5 JP 2024511463A5 JP 2023558515 A JP2023558515 A JP 2023558515A JP 2023558515 A JP2023558515 A JP 2023558515A JP 2024511463 A5 JP2024511463 A5 JP 2024511463A5
- Authority
- JP
- Japan
- Prior art keywords
- approximately
- lipid
- aerosol
- composition according
- aerosol composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163164523P | 2021-03-22 | 2021-03-22 | |
| US63/164,523 | 2021-03-22 | ||
| US202163229497P | 2021-08-04 | 2021-08-04 | |
| US63/229,497 | 2021-08-04 | ||
| US202263305426P | 2022-02-01 | 2022-02-01 | |
| US63/305,426 | 2022-02-01 | ||
| PCT/US2022/021442 WO2022204219A1 (en) | 2021-03-22 | 2022-03-22 | Compositions and methods for targeted delivery to cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024511463A JP2024511463A (ja) | 2024-03-13 |
| JP2024511463A5 true JP2024511463A5 (cg-RX-API-DMAC7.html) | 2025-04-01 |
Family
ID=83396024
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023558515A Pending JP2024511463A (ja) | 2021-03-22 | 2022-03-22 | 細胞への標的送達のための組成物および方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (10) | US20240207178A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP4312987A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2024511463A (cg-RX-API-DMAC7.html) |
| KR (1) | KR20240005692A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2022246065A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112023019229A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA3213299A1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL305782A (cg-RX-API-DMAC7.html) |
| MX (1) | MX2023011227A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2022204219A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102764250B1 (ko) * | 2015-09-14 | 2025-02-07 | 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 | 지질양이온성 덴드리머 및 이의 용도 |
| WO2022204043A1 (en) * | 2021-03-22 | 2022-09-29 | The Board Of Regents Of The University Of Texas System | Compositions and methods for targeted delivery to cells |
| MX2023011227A (es) | 2021-03-22 | 2023-12-06 | Recode Therapeutics Inc | Composiciones y metodos para administracion dirigida a celulas. |
| WO2022204053A1 (en) * | 2021-03-22 | 2022-09-29 | Recode Therapeutics, Inc. | Polynucleotide compositions, related formulations, and methods of use thereof |
| IL305958A (en) * | 2021-03-22 | 2023-11-01 | Recode Therapeutics Inc | Polynucleotide preparations, related formulations and methods of using them |
| KR20240024041A (ko) * | 2021-03-23 | 2024-02-23 | 리코드 테라퓨틱스, 인크. | 세포로의 표적화 전신 전달을 위한 조성물 및 방법 |
| MX2023011243A (es) | 2021-03-23 | 2023-12-14 | Recode Therapeutics Inc | Composiciones de polinucleotidos, formulaciones relacionadas y metodos de uso de los mismos. |
| JP2024516164A (ja) * | 2021-04-22 | 2024-04-12 | ザ ボード オブ リージェンツ オブ ザ ユニバーシティー オブ テキサス システム | 正確なインビボｈｄｒ介在性遺伝子編集を可能にするオールインワンデンドリマーベース脂質ナノ粒子 |
| IL321026A (en) | 2022-12-08 | 2025-07-01 | Recode Therapeutics Inc | Nanoparticle formulations and their uses |
| EP4385523A1 (en) * | 2022-12-14 | 2024-06-19 | Beijing Jitai Pharmaceutical Technology Co., Ltd. | Lipid-based topical injection formulations |
| CN116211831A (zh) * | 2022-12-14 | 2023-06-06 | 北京剂泰医药科技有限公司 | 脂质基质局部注射制剂 |
| CN120418427A (zh) | 2022-12-23 | 2025-08-01 | 因特利亚治疗公司 | 用于基因组编辑的系统和方法 |
| EP4719352A1 (en) | 2023-05-31 | 2026-04-08 | Capstan Therapeutics, Inc. | Lipid nanoparticle formulations and compositions |
| CN116983280B (zh) * | 2023-07-19 | 2025-09-30 | 南通大学 | 一种具有肺选择性的脂质纳米颗粒及其制备方法与应用 |
| WO2025075396A1 (ko) * | 2023-10-06 | 2025-04-10 | 한국과학기술연구원 | 타겟 핵산 검출물질이 담지된 지질 나노입자 및 이를 이용한 막융합 기반의 타겟 핵산 검출 방법 |
| AR134146A1 (es) * | 2023-10-24 | 2025-12-03 | Green Cross Corp | Lípidos ionizables y usos de los mismos |
| WO2025117816A1 (en) * | 2023-12-01 | 2025-06-05 | Recode Therapeutics, Inc. | Lipid nanoparticle compositions and uses thereof |
| US12553042B2 (en) | 2023-12-01 | 2026-02-17 | Recode Therapeutics, Inc. | Method for quantifying an amount of capped messenger RNA |
| US12364773B2 (en) | 2023-12-01 | 2025-07-22 | Recode Therapeutics, Inc. | Lipid nanoparticle compositions and uses thereof |
| WO2025137646A1 (en) * | 2023-12-22 | 2025-06-26 | Recode Therapeutics, Inc. | Gene editing methods and compositions for treating cystic fibrosis |
| KR20250110652A (ko) | 2024-01-12 | 2025-07-21 | 주식회사 엘지에너지솔루션 | 권취기 |
| CN117942406B (zh) * | 2024-01-19 | 2025-07-11 | 晟迪生物医药(苏州)有限公司 | 预制载体在制备用于免疫细胞和干细胞的体外基因递送的产品中的应用 |
| CN117919200B (zh) * | 2024-01-19 | 2025-09-05 | 晟迪生物医药(苏州)有限公司 | 含有可电离脂质的肺部递送系统、其制备方法和应用 |
| WO2025240355A1 (en) * | 2024-05-14 | 2025-11-20 | Recode Therapeutics, Inc. | Lipid nanoparticles for extrahepatic delivery |
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| US5820873A (en) | 1994-09-30 | 1998-10-13 | The University Of British Columbia | Polyethylene glycol modified ceramide lipids and liposome uses thereof |
| JP4335310B2 (ja) * | 1995-06-07 | 2009-09-30 | ザ ユニバーシティ オブ ブリティッシュ コロンビア | 疎水性脂質−核酸複合中間体を通して調製される脂質−核酸粒子、及び遺伝子移送のための使用 |
| EP0941066B1 (en) | 1996-08-26 | 2003-10-29 | Transgene S.A. | Cationic lipid-nucleic acid complexes |
| US5962429A (en) | 1996-11-22 | 1999-10-05 | University Of Iowa | Complexes of adenovirus with cationic molecules |
| ATE291925T1 (de) | 2001-06-05 | 2005-04-15 | Curevac Gmbh | Stabilisierte mrna mit erhöhtem g/c-gehalt und optimierter codon usage für die gentherapie |
| PL2578685T3 (pl) | 2005-08-23 | 2020-01-31 | The Trustees Of The University Of Pennsylvania | Rna zawierający zmodyfikowane nukleozydy i sposoby jego zastosowania |
| WO2010053572A2 (en) | 2008-11-07 | 2010-05-14 | Massachusetts Institute Of Technology | Aminoalcohol lipidoids and uses thereof |
| KR20220038506A (ko) | 2009-06-10 | 2022-03-28 | 알닐람 파마슈티칼스 인코포레이티드 | 향상된 지질 조성물 |
| SI2506857T1 (en) | 2009-12-01 | 2018-08-31 | Translate Bio, Inc. | Delivery of mRNA for the enrichment of proteins and enzymes in human genetic diseases |
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| KR20220025112A (ko) | 2011-06-08 | 2022-03-03 | 샤이어 휴먼 지네틱 테라피즈 인크. | Mrna 전달을 위한 지질 나노입자 조성물 및 방법 |
| BR112014024131A2 (pt) | 2012-03-29 | 2017-07-25 | Shire Human Genetic Therapies | lipídios catiônicos ionizáveis |
| HK1206644A1 (en) | 2012-03-29 | 2016-01-15 | Shire Human Genetic Therapies, Inc. | Lipid-derived neutral nanoparticles |
| EA201492055A1 (ru) | 2012-06-08 | 2015-11-30 | Шир Хьюман Дженетик Терапис, Инк. | ИНГАЛЯЦИОННАЯ ДОСТАВКА мРНК В НЕЛЕГОЧНЫЕ КЛЕТКИ-МИШЕНИ |
| ES3032935T3 (en) | 2013-10-22 | 2025-07-29 | Translate Bio Inc | Lipid formulations for delivery of messenger rna |
| US10059655B2 (en) | 2013-12-19 | 2018-08-28 | Novartis Ag | Lipids and lipid compositions for the delivery of active agents |
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| WO2016004202A1 (en) | 2014-07-02 | 2016-01-07 | Massachusetts Institute Of Technology | Polyamine-fatty acid derived lipidoids and uses thereof |
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| HUE067372T2 (hu) | 2015-06-29 | 2024-10-28 | Acuitas Therapeutics Inc | Lipidek és nanoszemcsés lipid formulázások nukleinsavak beadására |
| CA2990883A1 (en) | 2015-06-30 | 2017-01-05 | Ethris Gmbh | Atp-binding cassette family coding polyribonucleotides and formulations thereof |
| ES2898340T3 (es) | 2015-07-09 | 2022-03-07 | Insmed Inc | Composiciones y métodos para tratar neumopatías y lesión pulmonar |
| KR102764250B1 (ko) | 2015-09-14 | 2025-02-07 | 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 | 지질양이온성 덴드리머 및 이의 용도 |
| CN108368028B (zh) | 2015-10-28 | 2021-09-03 | 爱康泰生治疗公司 | 用于递送核酸的新型脂质和脂质纳米颗粒制剂 |
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| PL3458074T3 (pl) | 2016-05-16 | 2024-11-12 | Board Of Regents Of The University Of Texas System | KOMPOZYCJA DO DOSTARCZANIA tRNA W POSTACI NANOCZĄSTEK I SPOSOBY ICH STOSOWANIA |
| CN114656378A (zh) | 2016-05-16 | 2022-06-24 | 得克萨斯州大学系统董事会 | 阳离子磺酰胺氨基脂质和两亲性两性离子氨基脂质 |
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| EP4308703A4 (en) | 2021-03-19 | 2025-06-04 | Recode Therapeutics, Inc. | Polynucleotide compositions, associated formulations and methods of using the same |
| MX2023011227A (es) | 2021-03-22 | 2023-12-06 | Recode Therapeutics Inc | Composiciones y metodos para administracion dirigida a celulas. |
| WO2022204053A1 (en) | 2021-03-22 | 2022-09-29 | Recode Therapeutics, Inc. | Polynucleotide compositions, related formulations, and methods of use thereof |
| IL305958A (en) | 2021-03-22 | 2023-11-01 | Recode Therapeutics Inc | Polynucleotide preparations, related formulations and methods of using them |
| MX2023011243A (es) | 2021-03-23 | 2023-12-14 | Recode Therapeutics Inc | Composiciones de polinucleotidos, formulaciones relacionadas y metodos de uso de los mismos. |
| KR20240024041A (ko) | 2021-03-23 | 2024-02-23 | 리코드 테라퓨틱스, 인크. | 세포로의 표적화 전신 전달을 위한 조성물 및 방법 |
| AU2022253004A1 (en) | 2021-04-05 | 2023-10-12 | Recode Therapeutics, Inc. | Compositions, methods and uses for treating cystic fibrosis and related disorders |
| JP2024516164A (ja) | 2021-04-22 | 2024-04-12 | ザ ボード オブ リージェンツ オブ ザ ユニバーシティー オブ テキサス システム | 正確なインビボｈｄｒ介在性遺伝子編集を可能にするオールインワンデンドリマーベース脂質ナノ粒子 |
| JP2024520834A (ja) | 2021-06-09 | 2024-05-24 | レコード・セラピューティクス・インコーポレイテッド | ポリヌクレオチド組成物、関連する製剤及びその使用方法 |
| IL321026A (en) * | 2022-12-08 | 2025-07-01 | Recode Therapeutics Inc | Nanoparticle formulations and their uses |
| US12364773B2 (en) * | 2023-12-01 | 2025-07-22 | Recode Therapeutics, Inc. | Lipid nanoparticle compositions and uses thereof |
-
2022
- 2022-03-22 MX MX2023011227A patent/MX2023011227A/es unknown
- 2022-03-22 EP EP22776528.6A patent/EP4312987A4/en active Pending
- 2022-03-22 AU AU2022246065A patent/AU2022246065A1/en active Pending
- 2022-03-22 KR KR1020237035962A patent/KR20240005692A/ko active Pending
- 2022-03-22 IL IL305782A patent/IL305782A/en unknown
- 2022-03-22 CA CA3213299A patent/CA3213299A1/en active Pending
- 2022-03-22 US US18/283,344 patent/US20240207178A1/en active Pending
- 2022-03-22 WO PCT/US2022/021442 patent/WO2022204219A1/en not_active Ceased
- 2022-03-22 BR BR112023019229A patent/BR112023019229A2/pt unknown
- 2022-03-22 JP JP2023558515A patent/JP2024511463A/ja active Pending
-
2023
- 2023-05-03 US US18/311,616 patent/US12121610B2/en active Active
- 2023-05-03 US US18/311,274 patent/US20230293429A1/en not_active Abandoned
- 2023-05-04 US US18/312,305 patent/US20230338411A1/en not_active Abandoned
-
2024
- 2024-07-19 US US18/778,439 patent/US20240374512A1/en active Pending
- 2024-07-19 US US18/778,429 patent/US20240374511A1/en active Pending
- 2024-07-19 US US18/778,717 patent/US20240374513A1/en active Pending
- 2024-07-19 US US18/778,746 patent/US20240374514A1/en active Pending
- 2024-07-22 US US18/780,382 patent/US20240390271A1/en active Pending
- 2024-08-07 US US18/797,360 patent/US20240390272A1/en active Pending
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