JP2024508832A5 - - Google Patents
Info
- Publication number
- JP2024508832A5 JP2024508832A5 JP2023552064A JP2023552064A JP2024508832A5 JP 2024508832 A5 JP2024508832 A5 JP 2024508832A5 JP 2023552064 A JP2023552064 A JP 2023552064A JP 2023552064 A JP2023552064 A JP 2023552064A JP 2024508832 A5 JP2024508832 A5 JP 2024508832A5
- Authority
- JP
- Japan
- Prior art keywords
- oligonucleotide
- prosna
- sna
- shell
- core
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163154530P | 2021-02-26 | 2021-02-26 | |
| US63/154,530 | 2021-02-26 | ||
| US202163273086P | 2021-10-28 | 2021-10-28 | |
| US63/273,086 | 2021-10-28 | ||
| US202163290522P | 2021-12-16 | 2021-12-16 | |
| US63/290,522 | 2021-12-16 | ||
| PCT/US2022/017984 WO2022183043A1 (en) | 2021-02-26 | 2022-02-25 | Strategies to develop genome editing spherical nucleic acids (snas) |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024508832A JP2024508832A (ja) | 2024-02-28 |
| JP2024508832A5 true JP2024508832A5 (https=) | 2025-03-05 |
Family
ID=83049557
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023552064A Withdrawn JP2024508832A (ja) | 2021-02-26 | 2022-02-25 | ゲノム編集球状核酸(sna)を開発するための戦略 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20240318204A1 (https=) |
| EP (1) | EP4297729A4 (https=) |
| JP (1) | JP2024508832A (https=) |
| KR (1) | KR20230150852A (https=) |
| AU (1) | AU2022227771A1 (https=) |
| CA (1) | CA3209539A1 (https=) |
| WO (1) | WO2022183043A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12378560B2 (en) | 2019-10-29 | 2025-08-05 | Northwestern University | Sequence multiplicity within spherical nucleic acids |
| WO2024155879A1 (en) * | 2023-01-20 | 2024-07-25 | Northwestern University | ENHANCING BRAIN PERMEABILITY AND ACTIVITY OF GLUCOSYLCERAMIDASE (GCase) PROSNA FOR NEURODEGENERATIVE DISEASES |
| WO2025210133A1 (en) * | 2024-04-03 | 2025-10-09 | Deep Piction Gmbh | Hybrid lipid nanoparticles for targeted delivery |
| WO2025226642A1 (en) * | 2024-04-25 | 2025-10-30 | Eli Lilly And Company | Lipid nano delivery particles for targeted transport of nucleic acids and methods of making and using the same |
| WO2026006618A1 (en) * | 2024-06-26 | 2026-01-02 | Northwestern University | Lipid nanoparticle spherical nucleic acids for genome engineering |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016028940A1 (en) * | 2014-08-19 | 2016-02-25 | Northwestern University | Protein/oligonucleotide core-shell nanoparticle therapeutics |
| LT3436077T (lt) * | 2016-03-30 | 2025-06-25 | Intellia Therapeutics, Inc. | Lipidų nanodalelių vaisto formos, skirtos crispr/cas komponentams |
| WO2018213585A1 (en) * | 2017-05-17 | 2018-11-22 | Northwestern University | Conjugation of peptides to spherical nucleic acids (snas) using tracelless linkers |
| WO2019173728A1 (en) * | 2018-03-09 | 2019-09-12 | Lee Hye Young | Crispr-nanoparticles and methods of use in brain disorders |
| WO2019204531A1 (en) * | 2018-04-18 | 2019-10-24 | Ligandal, Inc. | Methods and compositions for genome editing |
| AU2019392748A1 (en) * | 2018-12-05 | 2021-06-10 | Fred Hutchinson Cancer Center | Reduced and minimal manipulation manufacturing of genetically-modified cells |
-
2022
- 2022-02-25 WO PCT/US2022/017984 patent/WO2022183043A1/en not_active Ceased
- 2022-02-25 CA CA3209539A patent/CA3209539A1/en active Pending
- 2022-02-25 US US18/279,034 patent/US20240318204A1/en active Pending
- 2022-02-25 KR KR1020237032913A patent/KR20230150852A/ko not_active Withdrawn
- 2022-02-25 EP EP22760522.7A patent/EP4297729A4/en active Pending
- 2022-02-25 AU AU2022227771A patent/AU2022227771A1/en not_active Abandoned
- 2022-02-25 JP JP2023552064A patent/JP2024508832A/ja not_active Withdrawn
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2024508832A5 (https=) | ||
| US8415461B2 (en) | Amphiphilic substances and functionalized lipid vesicles including the same | |
| Fattal et al. | “Smart” delivery of antisense oligonucleotides by anionic pH-sensitive liposomes | |
| ES2212305T3 (es) | Polinucleotidos encapsulados en liposomas, composicion y procedimiento. | |
| JP2024016183A5 (https=) | ||
| US9730893B2 (en) | Lipid assemblies comprising anionic lysolipids and use thereof | |
| Maurer et al. | Lipid-based systems for the intracellular delivery of genetic drugs | |
| Fenske et al. | Liposomal nanomedicines | |
| JP4203835B2 (ja) | 全身への送達を増加させる新規のリポソーム複合体 | |
| Smyth Templeton | Cationic liposome-mediated gene delivery in vivo | |
| JP2021535227A5 (https=) | ||
| US20200297867A1 (en) | Surface functionalization of liposomes and liposomal spherical nucleic acids (snas) | |
| CN101903018A (zh) | 用于递送核酸基因的ldl样阳离子纳米微粒、其制备方法以及使用其递送核酸基因的方法 | |
| CN108064295A (zh) | 具有核心基序的核酸纳米结构 | |
| JPH11511128A (ja) | リポソームオリゴヌクレオチド組成物 | |
| JP2001511440A (ja) | 層状構造の、中性あるいは陰性グローバル電荷を持つ安定粒状複合体 | |
| JP2024538168A (ja) | Dna組成物及び関連方法 | |
| JP2007524604A (ja) | 非対称の脂質被膜を有する脂質粒子およびその製造方法 | |
| WO2023141624A1 (en) | Ionizable lipids, lipid nanoparticles, and uses thereof | |
| Lin et al. | Development and clinical applications of siRNA-encapsulated lipid nanoparticles in cancer | |
| JP2001511171A (ja) | 安定化したカチオン性トランスフェクション用物質/核酸粒子の配合物 | |
| Lindner et al. | Structural variation of cationic lipids: minimum requirement for improved oligonucleotide delivery into cells | |
| Koynova et al. | Enhancing nucleic acid delivery, insights from the cationic phospholipid carriers | |
| JP4450656B2 (ja) | リポソームからなる遺伝子導入用キャリア | |
| Escriou et al. | Auto-associative lipid-based systems for non-viral nucleic acid delivery |