JP2024508832A5 - - Google Patents

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Publication number
JP2024508832A5
JP2024508832A5 JP2023552064A JP2023552064A JP2024508832A5 JP 2024508832 A5 JP2024508832 A5 JP 2024508832A5 JP 2023552064 A JP2023552064 A JP 2023552064A JP 2023552064 A JP2023552064 A JP 2023552064A JP 2024508832 A5 JP2024508832 A5 JP 2024508832A5
Authority
JP
Japan
Prior art keywords
oligonucleotide
prosna
sna
shell
core
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2023552064A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024508832A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/017984 external-priority patent/WO2022183043A1/en
Publication of JP2024508832A publication Critical patent/JP2024508832A/ja
Publication of JP2024508832A5 publication Critical patent/JP2024508832A5/ja
Withdrawn legal-status Critical Current

Links

JP2023552064A 2021-02-26 2022-02-25 ゲノム編集球状核酸(sna)を開発するための戦略 Withdrawn JP2024508832A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202163154530P 2021-02-26 2021-02-26
US63/154,530 2021-02-26
US202163273086P 2021-10-28 2021-10-28
US63/273,086 2021-10-28
US202163290522P 2021-12-16 2021-12-16
US63/290,522 2021-12-16
PCT/US2022/017984 WO2022183043A1 (en) 2021-02-26 2022-02-25 Strategies to develop genome editing spherical nucleic acids (snas)

Publications (2)

Publication Number Publication Date
JP2024508832A JP2024508832A (ja) 2024-02-28
JP2024508832A5 true JP2024508832A5 (https=) 2025-03-05

Family

ID=83049557

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023552064A Withdrawn JP2024508832A (ja) 2021-02-26 2022-02-25 ゲノム編集球状核酸(sna)を開発するための戦略

Country Status (7)

Country Link
US (1) US20240318204A1 (https=)
EP (1) EP4297729A4 (https=)
JP (1) JP2024508832A (https=)
KR (1) KR20230150852A (https=)
AU (1) AU2022227771A1 (https=)
CA (1) CA3209539A1 (https=)
WO (1) WO2022183043A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12378560B2 (en) 2019-10-29 2025-08-05 Northwestern University Sequence multiplicity within spherical nucleic acids
WO2024155879A1 (en) * 2023-01-20 2024-07-25 Northwestern University ENHANCING BRAIN PERMEABILITY AND ACTIVITY OF GLUCOSYLCERAMIDASE (GCase) PROSNA FOR NEURODEGENERATIVE DISEASES
WO2025210133A1 (en) * 2024-04-03 2025-10-09 Deep Piction Gmbh Hybrid lipid nanoparticles for targeted delivery
WO2025226642A1 (en) * 2024-04-25 2025-10-30 Eli Lilly And Company Lipid nano delivery particles for targeted transport of nucleic acids and methods of making and using the same
WO2026006618A1 (en) * 2024-06-26 2026-01-02 Northwestern University Lipid nanoparticle spherical nucleic acids for genome engineering

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016028940A1 (en) * 2014-08-19 2016-02-25 Northwestern University Protein/oligonucleotide core-shell nanoparticle therapeutics
LT3436077T (lt) * 2016-03-30 2025-06-25 Intellia Therapeutics, Inc. Lipidų nanodalelių vaisto formos, skirtos crispr/cas komponentams
WO2018213585A1 (en) * 2017-05-17 2018-11-22 Northwestern University Conjugation of peptides to spherical nucleic acids (snas) using tracelless linkers
WO2019173728A1 (en) * 2018-03-09 2019-09-12 Lee Hye Young Crispr-nanoparticles and methods of use in brain disorders
WO2019204531A1 (en) * 2018-04-18 2019-10-24 Ligandal, Inc. Methods and compositions for genome editing
AU2019392748A1 (en) * 2018-12-05 2021-06-10 Fred Hutchinson Cancer Center Reduced and minimal manipulation manufacturing of genetically-modified cells

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