JP2024504981A5 - - Google Patents

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Publication number
JP2024504981A5
JP2024504981A5 JP2023544203A JP2023544203A JP2024504981A5 JP 2024504981 A5 JP2024504981 A5 JP 2024504981A5 JP 2023544203 A JP2023544203 A JP 2023544203A JP 2023544203 A JP2023544203 A JP 2023544203A JP 2024504981 A5 JP2024504981 A5 JP 2024504981A5
Authority
JP
Japan
Application number
JP2023544203A
Other languages
Japanese (ja)
Other versions
JP2024504981A (ja
JPWO2022159758A5 (https=
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/013396 external-priority patent/WO2022159758A1/en
Publication of JP2024504981A publication Critical patent/JP2024504981A/ja
Publication of JP2024504981A5 publication Critical patent/JP2024504981A5/ja
Publication of JPWO2022159758A5 publication Critical patent/JPWO2022159758A5/ja
Pending legal-status Critical Current

Links

JP2023544203A 2021-01-22 2022-01-21 新規の操作されたヌクレアーゼおよびキメラヌクレアーゼ Pending JP2024504981A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163140620P 2021-01-22 2021-01-22
US63/140,620 2021-01-22
US202163237484P 2021-08-26 2021-08-26
US63/237,484 2021-08-26
PCT/US2022/013396 WO2022159758A1 (en) 2021-01-22 2022-01-21 Novel engineered and chimeric nucleases

Publications (3)

Publication Number Publication Date
JP2024504981A JP2024504981A (ja) 2024-02-02
JP2024504981A5 true JP2024504981A5 (https=) 2025-01-27
JPWO2022159758A5 JPWO2022159758A5 (https=) 2025-01-27

Family

ID=82549895

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023544203A Pending JP2024504981A (ja) 2021-01-22 2022-01-21 新規の操作されたヌクレアーゼおよびキメラヌクレアーゼ

Country Status (10)

Country Link
US (1) US20230416710A1 (https=)
EP (1) EP4281554A4 (https=)
JP (1) JP2024504981A (https=)
KR (1) KR20230134543A (https=)
AU (1) AU2022210762A1 (https=)
BR (1) BR112023014719A2 (https=)
CA (1) CA3205865A1 (https=)
GB (1) GB2610711B (https=)
MX (1) MX2023008629A (https=)
WO (1) WO2022159758A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2617658B (en) 2020-03-06 2024-04-17 Metagenomi Inc Class II, type V CRISPR systems
CA3225082A1 (en) * 2021-08-27 2023-03-02 Brian C. Thomas Enzymes with ruvc domains
WO2023178115A2 (en) * 2022-03-14 2023-09-21 Metagenomi, Inc. Engineered and chimeric nucleases
CN119546757A (zh) 2022-05-25 2025-02-28 宏基因组学公司 肝酶表达的补充
WO2023240076A1 (en) 2022-06-07 2023-12-14 Scribe Therapeutics Inc. Compositions and methods for the targeting of pcsk9
EP4562138A2 (en) * 2022-07-29 2025-06-04 Metagenomi, Inc. Class ii, type v crispr systems
WO2024156085A1 (en) * 2023-01-27 2024-08-02 Syngenta Crop Protection Ag Mb2cas12a variants with enhanced efficiency
KR20250153814A (ko) * 2023-03-01 2025-10-27 메타지노미, 인크. Ruvc 도메인을 갖는 효소
AU2024339645A1 (en) * 2023-09-13 2026-04-23 Metagenomi Therapeutics, Inc. Engineered and chimeric nucleases

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3363902B1 (en) * 2012-12-06 2019-11-27 Sigma Aldrich Co. LLC Crispr-based genome modification and regulation
US9963689B2 (en) * 2013-12-31 2018-05-08 The Regents Of The University Of California Cas9 crystals and methods of use thereof
WO2016205759A1 (en) * 2015-06-18 2016-12-22 The Broad Institute Inc. Engineering and optimization of systems, methods, enzymes and guide scaffolds of cas9 orthologs and variants for sequence manipulation
JP2020536502A (ja) * 2017-09-07 2020-12-17 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー 遺伝子操作のためのヌクレアーゼシステム
US12365888B2 (en) * 2018-12-14 2025-07-22 Pioneer Hi-Bred International, Inc. CRISPR-Cas systems for genome editing
AU2020223370B2 (en) * 2019-02-14 2023-04-20 Metagenomi Therapeutics, Inc. Enzymes with RuvC domains
US10913941B2 (en) * 2019-02-14 2021-02-09 Metagenomi Ip Technologies, Llc Enzymes with RuvC domains
KR20230021657A (ko) * 2020-05-08 2023-02-14 메타지노미, 인크. Ruvc 도메인을 포함하는 효소
CA3192224A1 (en) * 2020-09-11 2022-03-17 Jyun-Liang LIN Base editing enzymes
BR112023018948A2 (pt) * 2021-03-19 2023-10-17 Metagenomi Inc Edição multiplex com enzimas cas
AU2022380842A1 (en) * 2021-11-05 2024-05-23 Metagenomi Therapeutics, Inc. Base editing enzymes

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