JP2024504981A5 - - Google Patents
Info
- Publication number
- JP2024504981A5 JP2024504981A5 JP2023544203A JP2023544203A JP2024504981A5 JP 2024504981 A5 JP2024504981 A5 JP 2024504981A5 JP 2023544203 A JP2023544203 A JP 2023544203A JP 2023544203 A JP2023544203 A JP 2023544203A JP 2024504981 A5 JP2024504981 A5 JP 2024504981A5
- Authority
- JP
- Japan
- Prior art keywords
- sequence
- seq
- fusion
- fusion endonuclease
- endonuclease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163140620P | 2021-01-22 | 2021-01-22 | |
| US63/140,620 | 2021-01-22 | ||
| US202163237484P | 2021-08-26 | 2021-08-26 | |
| US63/237,484 | 2021-08-26 | ||
| PCT/US2022/013396 WO2022159758A1 (en) | 2021-01-22 | 2022-01-21 | Novel engineered and chimeric nucleases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024504981A JP2024504981A (ja) | 2024-02-02 |
| JP2024504981A5 true JP2024504981A5 (https=) | 2025-01-27 |
Family
ID=82549895
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023544203A Pending JP2024504981A (ja) | 2021-01-22 | 2022-01-21 | 新規の操作されたヌクレアーゼおよびキメラヌクレアーゼ |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20230416710A1 (https=) |
| EP (1) | EP4281554A4 (https=) |
| JP (1) | JP2024504981A (https=) |
| KR (1) | KR20230134543A (https=) |
| AU (1) | AU2022210762A1 (https=) |
| BR (1) | BR112023014719A2 (https=) |
| CA (1) | CA3205865A1 (https=) |
| GB (1) | GB2610711B (https=) |
| MX (1) | MX2023008629A (https=) |
| WO (1) | WO2022159758A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021178933A2 (en) | 2020-03-06 | 2021-09-10 | Metagenomi Ip Technologies, Llc | Class ii, type v crispr systems |
| AU2022335499A1 (en) | 2021-08-27 | 2024-02-22 | Metagenomi Therapeutics, Inc. | Enzymes with ruvc domains |
| AU2023235279A1 (en) * | 2022-03-14 | 2024-10-03 | Metagenomi Therapeutics, Inc. | Engineered and chimeric nucleases |
| AU2023276763A1 (en) | 2022-05-25 | 2024-12-12 | Metagenomi Therapeutics, Inc. | Supplementation of liver enzyme expression |
| GB2634837A (en) | 2022-06-07 | 2025-04-23 | Scribe Therapeutics Inc | Compositions and methods for the targeting of PCSK9 |
| JP2025527203A (ja) * | 2022-07-29 | 2025-08-20 | メタゲノミ，インク． | クラスｉｉ、ｖ型ｃｒｉｓｐｒ系 |
| CN120603942A (zh) * | 2023-01-27 | 2025-09-05 | 先正达农作物保护股份公司 | 具有增强的效率的Mb2Cas12a变体 |
| AU2024230342A1 (en) * | 2023-03-01 | 2025-10-16 | Metagenomi Therapeutics, Inc. | Enzymes with ruvc domains |
| WO2025059585A1 (en) * | 2023-09-13 | 2025-03-20 | Metagenomi, Inc. | Engineered and chimeric nucleases |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL3360964T3 (pl) * | 2012-12-06 | 2020-03-31 | Sigma-Aldrich Co. Llc | Modyfikacja i regulacja genomu oparta na crispr |
| EP3089989B1 (en) * | 2013-12-31 | 2020-06-24 | The Regents of The University of California | Cas9 crystals and methods of use thereof |
| WO2016205759A1 (en) * | 2015-06-18 | 2016-12-22 | The Broad Institute Inc. | Engineering and optimization of systems, methods, enzymes and guide scaffolds of cas9 orthologs and variants for sequence manipulation |
| CA3074872A1 (en) * | 2017-09-07 | 2019-03-14 | The Board Of Trustees Of The Leland Stanford Junior University | Nuclease systems for genetic engineering |
| WO2020123887A2 (en) * | 2018-12-14 | 2020-06-18 | Pioneer Hi-Bred International, Inc. | Novel crispr-cas systems for genome editing |
| WO2021226363A1 (en) * | 2020-05-08 | 2021-11-11 | Metagenomi Ip Technologies, Llc | Enzymes with ruvc domains |
| CA3241703C (en) * | 2019-02-14 | 2026-02-24 | Metagenomi Therapeutics, Inc. | Enzymes with ruvc domains |
| US10913941B2 (en) * | 2019-02-14 | 2021-02-09 | Metagenomi Ip Technologies, Llc | Enzymes with RuvC domains |
| JP2023540797A (ja) * | 2020-09-11 | 2023-09-26 | メタゲノミ，インコーポレイテッド | 塩基編集酵素 |
| JP2024515936A (ja) * | 2021-03-19 | 2024-04-11 | メタゲノミ，インク． | Ｃａｓ酵素を用いたマルチプレックス編集 |
| WO2023081855A1 (en) * | 2021-11-05 | 2023-05-11 | Metagenomi, Inc. | Base editing enzymes |
-
2022
- 2022-01-21 CA CA3205865A patent/CA3205865A1/en active Pending
- 2022-01-21 AU AU2022210762A patent/AU2022210762A1/en active Pending
- 2022-01-21 GB GB2215621.0A patent/GB2610711B/en active Active
- 2022-01-21 KR KR1020237028011A patent/KR20230134543A/ko active Pending
- 2022-01-21 MX MX2023008629A patent/MX2023008629A/es unknown
- 2022-01-21 WO PCT/US2022/013396 patent/WO2022159758A1/en not_active Ceased
- 2022-01-21 EP EP22743281.2A patent/EP4281554A4/en active Pending
- 2022-01-21 JP JP2023544203A patent/JP2024504981A/ja active Pending
- 2022-01-21 BR BR112023014719A patent/BR112023014719A2/pt unknown
- 2022-11-17 US US18/056,629 patent/US20230416710A1/en active Pending
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