JP2024170524A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2024170524A5 JP2024170524A5 JP2024152052A JP2024152052A JP2024170524A5 JP 2024170524 A5 JP2024170524 A5 JP 2024170524A5 JP 2024152052 A JP2024152052 A JP 2024152052A JP 2024152052 A JP2024152052 A JP 2024152052A JP 2024170524 A5 JP2024170524 A5 JP 2024170524A5
- Authority
- JP
- Japan
- Prior art keywords
- nfkb
- nfat
- stat4
- sequence
- tre
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762507565P | 2017-05-17 | 2017-05-17 | |
| US62/507,565 | 2017-05-17 | ||
| PCT/US2018/032800 WO2018213332A1 (en) | 2017-05-17 | 2018-05-15 | Generating mammalian t cell activation inducible synthetic promoters (syn+pro) to improve t cell therapy |
| JP2019563586A JP7264329B2 (ja) | 2017-05-17 | 2018-05-15 | Ｔ細胞療法を向上させるための、哺乳動物ｔ細胞の活性化により誘導可能な合成プロモーター（ｓｙｎ＋ｐｒｏ）の作製 |
| JP2023052632A JP7551815B2 (ja) | 2017-05-17 | 2023-03-29 | Ｔ細胞療法を向上させるための、哺乳動物ｔ細胞の活性化により誘導可能な合成プロモーター（ｓｙｎ＋ｐｒｏ）の作製 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023052632A Division JP7551815B2 (ja) | 2017-05-17 | 2023-03-29 | Ｔ細胞療法を向上させるための、哺乳動物ｔ細胞の活性化により誘導可能な合成プロモーター（ｓｙｎ＋ｐｒｏ）の作製 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024170524A JP2024170524A (ja) | 2024-12-10 |
| JP2024170524A5 true JP2024170524A5 (https=) | 2025-05-12 |
Family
ID=64274798
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019563586A Active JP7264329B2 (ja) | 2017-05-17 | 2018-05-15 | Ｔ細胞療法を向上させるための、哺乳動物ｔ細胞の活性化により誘導可能な合成プロモーター（ｓｙｎ＋ｐｒｏ）の作製 |
| JP2023052632A Active JP7551815B2 (ja) | 2017-05-17 | 2023-03-29 | Ｔ細胞療法を向上させるための、哺乳動物ｔ細胞の活性化により誘導可能な合成プロモーター（ｓｙｎ＋ｐｒｏ）の作製 |
| JP2024152052A Pending JP2024170524A (ja) | 2017-05-17 | 2024-09-04 | Ｔ細胞療法を向上させるための、哺乳動物ｔ細胞の活性化により誘導可能な合成プロモーター（ｓｙｎ＋ｐｒｏ）の作製 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019563586A Active JP7264329B2 (ja) | 2017-05-17 | 2018-05-15 | Ｔ細胞療法を向上させるための、哺乳動物ｔ細胞の活性化により誘導可能な合成プロモーター（ｓｙｎ＋ｐｒｏ）の作製 |
| JP2023052632A Active JP7551815B2 (ja) | 2017-05-17 | 2023-03-29 | Ｔ細胞療法を向上させるための、哺乳動物ｔ細胞の活性化により誘導可能な合成プロモーター（ｓｙｎ＋ｐｒｏ）の作製 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US11851649B2 (https=) |
| EP (3) | EP3624814A4 (https=) |
| JP (3) | JP7264329B2 (https=) |
| CN (3) | CN118374493A (https=) |
| AU (2) | AU2018270156B2 (https=) |
| CA (1) | CA3063695A1 (https=) |
| WO (1) | WO2018213332A1 (https=) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4282419A1 (en) | 2012-12-20 | 2023-11-29 | Purdue Research Foundation | Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics |
| EP3439675A4 (en) | 2016-04-08 | 2019-12-18 | Purdue Research Foundation | METHOD AND COMPOSITIONS FOR CAR-T CELL THERAPY |
| WO2018160622A1 (en) | 2017-02-28 | 2018-09-07 | Endocyte, Inc. | Compositions and methods for car t cell therapy |
| US20210130775A1 (en) * | 2017-08-02 | 2021-05-06 | Autolus Limited | Cells expressing a chimeric antigen receptor or engineered tcr and comprising a nucleotide sequence which is selectively expressed |
| AU2018329741B2 (en) | 2017-09-08 | 2025-02-20 | Poseida Therapeutics, Inc. | Compositions and methods for chimeric ligand receptor (CLR)-mediated conditional gene expression |
| US11311576B2 (en) | 2018-01-22 | 2022-04-26 | Seattle Children's Hospital | Methods of use for CAR T cells |
| AU2019225174B2 (en) | 2018-02-23 | 2025-11-20 | Endocyte, Inc. | Sequencing method for CAR T cell therapy |
| KR20210122814A (ko) * | 2019-02-01 | 2021-10-12 | 시애틀 칠드런즈 호스피탈 디/비/에이 시애틀 칠드런즈 리서치 인스티튜트 | 조작된 유전자 발현을 조절하기 위한 미세환경 센서 |
| EP3922721A4 (en) * | 2019-03-12 | 2023-01-11 | Chongqing Precision Biotech Company Limited | PROMOTER REGULATED BY HYPOXIA AND ITS APPLICATION |
| WO2021231569A1 (en) * | 2020-05-14 | 2021-11-18 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Dual promoter systems |
| WO2021259334A1 (zh) * | 2020-06-24 | 2021-12-30 | 南京博望医药科技有限公司 | 自我调节型嵌合抗原受体及其在肿瘤免疫中的应用 |
| US20240043868A1 (en) * | 2020-09-21 | 2024-02-08 | Fundación Pública Andaluza Progreso Y Salud | Polynucleotide for physiological expression in t-cells |
| ES2901575A1 (es) * | 2020-09-21 | 2022-03-22 | Fund Publica Andaluza Progreso Y Salud | Polinucleótido para expresión fisiológica en células T |
| KR20220113092A (ko) * | 2021-02-05 | 2022-08-12 | 바이젠셀 주식회사 | 변형된 살해 세포, 이의 제조방법 및 이의 약제학적 용도 |
| WO2022212879A1 (en) | 2021-04-01 | 2022-10-06 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Il-13ra2 chimeric antigen receptors and methods of use |
| US20240207319A1 (en) | 2021-05-06 | 2024-06-27 | Ludwig Institute For Cancer Research Ltd | Compositions and methods for immunotherapy |
| EP4377464A4 (en) * | 2021-07-29 | 2025-07-09 | Seattle Childrens Hospital D/B/A Seattle Childrens Res Institute | SYNTHETIC NUCLEIC ACID ELEMENTS TO IMPROVE CAR-T CELL EFFICACY |
| US20250009802A1 (en) | 2021-12-16 | 2025-01-09 | Ludwig Institute For Cancer Research Ltd | Antisense transfer vectors and methods of use thereof |
| CN116813794B (zh) * | 2023-02-27 | 2024-07-12 | 武汉波睿达生物科技有限公司 | 共表达spi1的嵌合抗原受体及其应用 |
| EP4694897A1 (en) * | 2023-04-14 | 2026-02-18 | Seattle Children's Hospital d/b/a Seattle Children's Research Institute | Inducible programmed cell death-1 (pd1)-cytokine chimera for potentiated immune cell function |
| WO2024229126A2 (en) * | 2023-05-01 | 2024-11-07 | Seattle Children's Hospital D/B/A Seattle Children's Research Institute | Mutant interleukin 15 expressing immune cells |
| WO2024243460A1 (en) * | 2023-05-23 | 2024-11-28 | Abintus Bio, Inc. | Vectors and methods for in vivo transduction |
| CN119530217A (zh) * | 2023-08-30 | 2025-02-28 | 徐州医科大学 | T细胞激活后特异诱导基因表达的重组启动子系统 |
| CN120112648A (zh) * | 2023-09-22 | 2025-06-06 | 京东方科技集团股份有限公司 | 一种免疫细胞的制备方法 |
| WO2025076415A1 (en) * | 2023-10-06 | 2025-04-10 | Seattle Children's Hospital D/B/A Seattle Children's Research Institute | Inducible transgenes encoding intracellular molecules for modulating immune cell function |
| WO2025085511A1 (en) * | 2023-10-18 | 2025-04-24 | University Of Washington | Systems and methods for polymer-mediated activation of engineered cells |
| WO2025199252A1 (en) * | 2024-03-19 | 2025-09-25 | Seattle Children's Hospital D/B/A Seattle Children's Research Institute | Inducible transcription factor expression for modulating immune cell function |
| WO2026025092A1 (en) * | 2024-07-26 | 2026-01-29 | Juno Therapeutics, Inc. | Synthetic promoters for t cell expression |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2390399A1 (en) * | 2000-12-27 | 2002-07-04 | Geneka Biotechnology Inc. | Methods for selecting and producing selective pharmaceutical compounds and compositions using an established genetically altered cell-based library responsive to transcription factors; genetic constructs and library therefor |
| CA2327581A1 (en) | 2000-12-27 | 2002-06-27 | Yves Blais | Methods and compositions for the establishment of genetically altered cell-based library designed for monitoring transcriptional activity of compounds and molecules |
| WO2004031357A2 (en) * | 2002-10-01 | 2004-04-15 | Duke University | Targeted tumor therapy by use of recombinant adenovirus vectors that selectively replicate in hypoxic regions of tumors |
| EP2046818A4 (en) * | 2006-07-11 | 2010-03-03 | Leap Biosciences Corp | METHOD FOR THE SELECTIVE ENRICHMENT OF PROTEINS AND APPLICATIONS |
| US20110165568A1 (en) * | 2009-12-31 | 2011-07-07 | Life Technologies Corporation | Sequences of e.coli 055:h7 genome |
| US10391126B2 (en) * | 2011-11-18 | 2019-08-27 | Board Of Regents, The University Of Texas System | CAR+ T cells genetically modified to eliminate expression of T-cell receptor and/or HLA |
| CA3285826A1 (en) | 2012-02-22 | 2026-03-02 | The Trustees Of The University Of Pennsylvania | Compositions and methods for generating a persisting population of t cells useful for the treatment of cancer |
| BR122020002986A8 (pt) * | 2012-08-20 | 2023-04-18 | Seattle Childrens Hospital Dba Seattle Childrens Res Inst | Método e composições para imunoterapia celular |
| DK2986311T3 (en) * | 2013-04-18 | 2019-02-25 | Tilt Biotherapeutics Oy | IMPROVED ADOPTIVE CELL THERAPY |
| WO2015079053A2 (en) * | 2013-11-29 | 2015-06-04 | Ucb Biopharma Sprl | Synthetic promoters |
| WO2015092024A2 (en) | 2013-12-20 | 2015-06-25 | Cellectis | Method of engineering multi-input signal sensitive t cell for immunotherapy |
| US10611837B2 (en) * | 2014-04-10 | 2020-04-07 | Seattle Children's Hospital | Transgene genetic tags and methods of use |
| JP6827319B2 (ja) | 2014-05-08 | 2021-02-10 | 中外製薬株式会社 | Ｇｐｃ３標的治療剤療法が有効である患者に投与されるｇｐｃ３標的治療剤 |
| KR20170068504A (ko) * | 2014-10-08 | 2017-06-19 | 노파르티스 아게 | 키메라 항원 수용체 요법에 대한 치료 반응성을 예측하는 바이오마커 및 그의 용도 |
| WO2016100575A1 (en) * | 2014-12-16 | 2016-06-23 | Board Of Regents Of The University Of Nebraska | Gene therapy for juvenile batten disease |
| KR102624023B1 (ko) * | 2015-02-24 | 2024-01-11 | 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 | 결합-촉발된 전사 스위치 및 이들의 이용 방법 |
| JP6961490B2 (ja) * | 2015-04-08 | 2021-11-05 | ノバルティス アーゲー | Ｃｄ２０療法、ｃｄ２２療法、およびｃｄ１９キメラ抗原受容体（ｃａｒ）発現細胞との併用療法 |
| EP3288568A4 (en) * | 2015-04-30 | 2019-01-02 | University of Southern California | Secretory tnt car cell immunotherapy |
| EP3347026A4 (en) * | 2015-09-09 | 2019-05-08 | Seattle Children's Hospital (DBA Seattle Children's Research Institute) | GENEMANIPULATION OF MACROPHAGES FOR IMMUNOTHERAPY |
-
2018
- 2018-05-15 CN CN202410174641.2A patent/CN118374493A/zh active Pending
- 2018-05-15 CA CA3063695A patent/CA3063695A1/en active Pending
- 2018-05-15 WO PCT/US2018/032800 patent/WO2018213332A1/en not_active Ceased
- 2018-05-15 CN CN201880047704.0A patent/CN110913871B/zh active Active
- 2018-05-15 AU AU2018270156A patent/AU2018270156B2/en active Active
- 2018-05-15 EP EP18803169.4A patent/EP3624814A4/en active Pending
- 2018-05-15 CN CN202410163430.9A patent/CN118147137A/zh active Pending
- 2018-05-15 EP EP25186763.6A patent/EP4613864A3/en active Pending
- 2018-05-15 EP EP24169900.8A patent/EP4389900A3/en not_active Withdrawn
- 2018-05-15 JP JP2019563586A patent/JP7264329B2/ja active Active
- 2018-05-15 US US16/613,025 patent/US11851649B2/en active Active
-
2023
- 2023-03-29 JP JP2023052632A patent/JP7551815B2/ja active Active
- 2023-07-20 AU AU2023206169A patent/AU2023206169B2/en active Active
- 2023-11-27 US US18/520,117 patent/US20240093178A1/en active Pending
-
2024
- 2024-09-04 JP JP2024152052A patent/JP2024170524A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2024170524A5 (https=) | ||
| IL299249B1 (en) | Genetically modified immune cells that include adapted shrna-microRNA (shrnamir) | |
| Jeong et al. | Genome sequences of Escherichia coli B strains REL606 and BL21 (DE3) | |
| JP2023116674A5 (https=) | ||
| Perez et al. | The small RING finger protein Z drives arenavirus budding: implications for antiviral strategies | |
| Finke et al. | Dissociation of rabies virus matrix protein functions in regulation of viral RNA synthesis and virus assembly | |
| Gómara et al. | Amino acid substitution within the VP7 protein of G2 rotavirus strains associated with failure to serotype | |
| Mann et al. | The genome of S-PM2, a “photosynthetic” T4-type bacteriophage that infects marine Synechococcus strains | |
| JP2022503959A5 (https=) | ||
| JP2023511527A5 (https=) | ||
| JP2023511523A5 (https=) | ||
| Li et al. | Sequence and phylogenetic analysis of nucleocapsid genes of porcine epidemic diarrhea virus (PEDV) strains in China | |
| JP2017122120A5 (https=) | ||
| BYERS et al. | Genes of Acanthamoeba: DNA, RNA and Protein Sequences (A Review) 1 | |
| CN110054668A (zh) | 一种呼吸道合胞病毒融合前f蛋白及其应用 | |
| JP2022164822A5 (https=) | ||
| Shafiq et al. | Evidence of genetic reassortment between Indian isolate of bluetongue virus serotype 21 (BTV-21) and bluetongue virus serotype 16 (BTV-16) | |
| CN105331635A (zh) | 一种诱导型慢病毒表达体系及其构建方法和应用 | |
| JP2008545436A5 (https=) | ||
| JP2019521154A5 (https=) | ||
| JP2023171909A5 (https=) | ||
| Falkenhagen et al. | Genetic and biological characteristics of species A rotaviruses detected in common shrews suggest a distinct evolutionary trajectory | |
| CN104946686A (zh) | 用于表达猪流行性腹泻蛋白中m蛋白、n蛋白和s1蛋白的重组质粒及其构建方法和应用 | |
| Beier et al. | Intraspecies polymorphism of vsp genes and expression profiles of variable surface protein antigens (Vsps) in field isolates of Mycoplasma bovis | |
| JP2024038256A5 (https=) |