JP7264329B2 - T細胞療法を向上させるための、哺乳動物t細胞の活性化により誘導可能な合成プロモーター(syn+pro)の作製 - Google Patents
T細胞療法を向上させるための、哺乳動物t細胞の活性化により誘導可能な合成プロモーター(syn+pro)の作製 Download PDFInfo
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023052632A JP7551815B2 (ja) | 2017-05-17 | 2023-03-29 | T細胞療法を向上させるための、哺乳動物t細胞の活性化により誘導可能な合成プロモーター(syn+pro)の作製 |
| JP2024152052A JP2024170524A (ja) | 2017-05-17 | 2024-09-04 | T細胞療法を向上させるための、哺乳動物t細胞の活性化により誘導可能な合成プロモーター(syn+pro)の作製 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762507565P | 2017-05-17 | 2017-05-17 | |
| US62/507,565 | 2017-05-17 | ||
| PCT/US2018/032800 WO2018213332A1 (en) | 2017-05-17 | 2018-05-15 | Generating mammalian t cell activation inducible synthetic promoters (syn+pro) to improve t cell therapy |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023052632A Division JP7551815B2 (ja) | 2017-05-17 | 2023-03-29 | T細胞療法を向上させるための、哺乳動物t細胞の活性化により誘導可能な合成プロモーター(syn+pro)の作製 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020520922A JP2020520922A (ja) | 2020-07-16 |
| JP7264329B2 true JP7264329B2 (ja) | 2023-04-25 |
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Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019563586A Active JP7264329B2 (ja) | 2017-05-17 | 2018-05-15 | T細胞療法を向上させるための、哺乳動物t細胞の活性化により誘導可能な合成プロモーター(syn+pro)の作製 |
| JP2023052632A Active JP7551815B2 (ja) | 2017-05-17 | 2023-03-29 | T細胞療法を向上させるための、哺乳動物t細胞の活性化により誘導可能な合成プロモーター(syn+pro)の作製 |
| JP2024152052A Pending JP2024170524A (ja) | 2017-05-17 | 2024-09-04 | T細胞療法を向上させるための、哺乳動物t細胞の活性化により誘導可能な合成プロモーター(syn+pro)の作製 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023052632A Active JP7551815B2 (ja) | 2017-05-17 | 2023-03-29 | T細胞療法を向上させるための、哺乳動物t細胞の活性化により誘導可能な合成プロモーター(syn+pro)の作製 |
| JP2024152052A Pending JP2024170524A (ja) | 2017-05-17 | 2024-09-04 | T細胞療法を向上させるための、哺乳動物t細胞の活性化により誘導可能な合成プロモーター(syn+pro)の作製 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US11851649B2 (https=) |
| EP (3) | EP3624814A4 (https=) |
| JP (3) | JP7264329B2 (https=) |
| CN (3) | CN118374493A (https=) |
| AU (2) | AU2018270156B2 (https=) |
| CA (1) | CA3063695A1 (https=) |
| WO (1) | WO2018213332A1 (https=) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
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| EP4282419A1 (en) | 2012-12-20 | 2023-11-29 | Purdue Research Foundation | Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics |
| EP3439675A4 (en) | 2016-04-08 | 2019-12-18 | Purdue Research Foundation | METHOD AND COMPOSITIONS FOR CAR-T CELL THERAPY |
| WO2018160622A1 (en) | 2017-02-28 | 2018-09-07 | Endocyte, Inc. | Compositions and methods for car t cell therapy |
| US20210130775A1 (en) * | 2017-08-02 | 2021-05-06 | Autolus Limited | Cells expressing a chimeric antigen receptor or engineered tcr and comprising a nucleotide sequence which is selectively expressed |
| AU2018329741B2 (en) | 2017-09-08 | 2025-02-20 | Poseida Therapeutics, Inc. | Compositions and methods for chimeric ligand receptor (CLR)-mediated conditional gene expression |
| US11311576B2 (en) | 2018-01-22 | 2022-04-26 | Seattle Children's Hospital | Methods of use for CAR T cells |
| AU2019225174B2 (en) | 2018-02-23 | 2025-11-20 | Endocyte, Inc. | Sequencing method for CAR T cell therapy |
| KR20210122814A (ko) * | 2019-02-01 | 2021-10-12 | 시애틀 칠드런즈 호스피탈 디/비/에이 시애틀 칠드런즈 리서치 인스티튜트 | 조작된 유전자 발현을 조절하기 위한 미세환경 센서 |
| EP3922721A4 (en) * | 2019-03-12 | 2023-01-11 | Chongqing Precision Biotech Company Limited | PROMOTER REGULATED BY HYPOXIA AND ITS APPLICATION |
| WO2021231569A1 (en) * | 2020-05-14 | 2021-11-18 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Dual promoter systems |
| WO2021259334A1 (zh) * | 2020-06-24 | 2021-12-30 | 南京博望医药科技有限公司 | 自我调节型嵌合抗原受体及其在肿瘤免疫中的应用 |
| US20240043868A1 (en) * | 2020-09-21 | 2024-02-08 | Fundación Pública Andaluza Progreso Y Salud | Polynucleotide for physiological expression in t-cells |
| ES2901575A1 (es) * | 2020-09-21 | 2022-03-22 | Fund Publica Andaluza Progreso Y Salud | Polinucleótido para expresión fisiológica en células T |
| KR20220113092A (ko) * | 2021-02-05 | 2022-08-12 | 바이젠셀 주식회사 | 변형된 살해 세포, 이의 제조방법 및 이의 약제학적 용도 |
| WO2022212879A1 (en) | 2021-04-01 | 2022-10-06 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Il-13ra2 chimeric antigen receptors and methods of use |
| US20240207319A1 (en) | 2021-05-06 | 2024-06-27 | Ludwig Institute For Cancer Research Ltd | Compositions and methods for immunotherapy |
| EP4377464A4 (en) * | 2021-07-29 | 2025-07-09 | Seattle Childrens Hospital D/B/A Seattle Childrens Res Institute | SYNTHETIC NUCLEIC ACID ELEMENTS TO IMPROVE CAR-T CELL EFFICACY |
| US20250009802A1 (en) | 2021-12-16 | 2025-01-09 | Ludwig Institute For Cancer Research Ltd | Antisense transfer vectors and methods of use thereof |
| CN116813794B (zh) * | 2023-02-27 | 2024-07-12 | 武汉波睿达生物科技有限公司 | 共表达spi1的嵌合抗原受体及其应用 |
| EP4694897A1 (en) * | 2023-04-14 | 2026-02-18 | Seattle Children's Hospital d/b/a Seattle Children's Research Institute | Inducible programmed cell death-1 (pd1)-cytokine chimera for potentiated immune cell function |
| WO2024229126A2 (en) * | 2023-05-01 | 2024-11-07 | Seattle Children's Hospital D/B/A Seattle Children's Research Institute | Mutant interleukin 15 expressing immune cells |
| WO2024243460A1 (en) * | 2023-05-23 | 2024-11-28 | Abintus Bio, Inc. | Vectors and methods for in vivo transduction |
| CN119530217A (zh) * | 2023-08-30 | 2025-02-28 | 徐州医科大学 | T细胞激活后特异诱导基因表达的重组启动子系统 |
| CN120112648A (zh) * | 2023-09-22 | 2025-06-06 | 京东方科技集团股份有限公司 | 一种免疫细胞的制备方法 |
| WO2025076415A1 (en) * | 2023-10-06 | 2025-04-10 | Seattle Children's Hospital D/B/A Seattle Children's Research Institute | Inducible transgenes encoding intracellular molecules for modulating immune cell function |
| WO2025085511A1 (en) * | 2023-10-18 | 2025-04-24 | University Of Washington | Systems and methods for polymer-mediated activation of engineered cells |
| WO2025199252A1 (en) * | 2024-03-19 | 2025-09-25 | Seattle Children's Hospital D/B/A Seattle Children's Research Institute | Inducible transcription factor expression for modulating immune cell function |
| WO2026025092A1 (en) * | 2024-07-26 | 2026-01-29 | Juno Therapeutics, Inc. | Synthetic promoters for t cell expression |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016164731A2 (en) | 2015-04-08 | 2016-10-13 | Novartis Ag | Cd20 therapies, cd22 therapies, and combination therapies with a cd19 chimeric antigen receptor (car) - expressing cell |
| WO2016176639A1 (en) | 2015-04-30 | 2016-11-03 | University Of Southern California | Secretory tnt car cell immunotherapy |
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| WO2016164731A2 (en) | 2015-04-08 | 2016-10-13 | Novartis Ag | Cd20 therapies, cd22 therapies, and combination therapies with a cd19 chimeric antigen receptor (car) - expressing cell |
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| WO2018213332A1 (en) | 2018-11-22 |
| JP2020520922A (ja) | 2020-07-16 |
| CN110913871B (zh) | 2024-02-23 |
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| EP4613864A3 (en) | 2026-04-15 |
| AU2018270156A1 (en) | 2019-12-19 |
| EP4613864A2 (en) | 2025-09-10 |
| JP2024170524A (ja) | 2024-12-10 |
| US11851649B2 (en) | 2023-12-26 |
| US20240093178A1 (en) | 2024-03-21 |
| AU2023206169A1 (en) | 2023-08-10 |
| JP2023085399A (ja) | 2023-06-20 |
| EP4389900A3 (en) | 2024-12-18 |
| CN118374493A (zh) | 2024-07-23 |
| AU2018270156B2 (en) | 2023-04-20 |
| EP4389900A2 (en) | 2024-06-26 |
| CA3063695A1 (en) | 2018-11-22 |
| AU2023206169B2 (en) | 2026-02-19 |
| JP7551815B2 (ja) | 2024-09-17 |
| EP3624814A1 (en) | 2020-03-25 |
| EP3624814A4 (en) | 2021-02-24 |
| CN118147137A (zh) | 2024-06-07 |
| CN110913871A (zh) | 2020-03-24 |
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