JP2024009130A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2024009130A5 JP2024009130A5 JP2023196673A JP2023196673A JP2024009130A5 JP 2024009130 A5 JP2024009130 A5 JP 2024009130A5 JP 2023196673 A JP2023196673 A JP 2023196673A JP 2023196673 A JP2023196673 A JP 2023196673A JP 2024009130 A5 JP2024009130 A5 JP 2024009130A5
- Authority
- JP
- Japan
- Prior art keywords
- hydrogel scaffold
- composition
- tooth
- hydrogel
- scaffold
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000017 hydrogel Substances 0.000 claims 32
- 239000000203 mixture Substances 0.000 claims 19
- 210000003074 dental pulp Anatomy 0.000 claims 5
- SQDAZGGFXASXDW-UHFFFAOYSA-N 5-bromo-2-(trifluoromethoxy)pyridine Chemical compound FC(F)(F)OC1=CC=C(Br)C=N1 SQDAZGGFXASXDW-UHFFFAOYSA-N 0.000 claims 4
- 229920001287 Chondroitin sulfate Polymers 0.000 claims 4
- 229940059329 chondroitin sulfate Drugs 0.000 claims 4
- 210000004262 dental pulp cavity Anatomy 0.000 claims 4
- 238000000034 method Methods 0.000 claims 4
- 229920000642 polymer Polymers 0.000 claims 4
- 229920000045 Dermatan sulfate Polymers 0.000 claims 3
- 108010010803 Gelatin Proteins 0.000 claims 3
- 229920002971 Heparan sulfate Polymers 0.000 claims 3
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 claims 3
- 108010076876 Keratins Proteins 0.000 claims 3
- 102000011782 Keratins Human genes 0.000 claims 3
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 claims 3
- AVJBPWGFOQAPRH-FWMKGIEWSA-L dermatan sulfate Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@H](OS([O-])(=O)=O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](C([O-])=O)O1 AVJBPWGFOQAPRH-FWMKGIEWSA-L 0.000 claims 3
- 229940051593 dermatan sulfate Drugs 0.000 claims 3
- 239000008273 gelatin Substances 0.000 claims 3
- 229920000159 gelatin Polymers 0.000 claims 3
- 235000019322 gelatine Nutrition 0.000 claims 3
- 235000011852 gelatine desserts Nutrition 0.000 claims 3
- 229920000669 heparin Polymers 0.000 claims 3
- 229960002897 heparin Drugs 0.000 claims 3
- 238000011065 in-situ storage Methods 0.000 claims 3
- 230000008595 infiltration Effects 0.000 claims 3
- 238000001764 infiltration Methods 0.000 claims 3
- 230000002491 angiogenic effect Effects 0.000 claims 2
- 239000003181 biological factor Substances 0.000 claims 2
- 230000003399 chemotactic effect Effects 0.000 claims 2
- 208000002925 dental caries Diseases 0.000 claims 2
- 150000004676 glycans Chemical class 0.000 claims 2
- 230000002519 immonomodulatory effect Effects 0.000 claims 2
- 230000001272 neurogenic effect Effects 0.000 claims 2
- 229920001282 polysaccharide Polymers 0.000 claims 2
- 239000005017 polysaccharide Substances 0.000 claims 2
- 206010061218 Inflammation Diseases 0.000 claims 1
- 230000001413 cellular effect Effects 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 230000004054 inflammatory process Effects 0.000 claims 1
- 230000001172 regenerating effect Effects 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862645364P | 2018-03-20 | 2018-03-20 | |
| US62/645,364 | 2018-03-20 | ||
| PCT/US2019/023132 WO2019183201A1 (en) | 2018-03-20 | 2019-03-20 | Regeneration of vital tooth pulp |
| JP2020550177A JP7406809B2 (ja) | 2018-03-20 | 2019-03-20 | 活力のある歯髄の再生 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020550177A Division JP7406809B2 (ja) | 2018-03-20 | 2019-03-20 | 活力のある歯髄の再生 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024009130A JP2024009130A (ja) | 2024-01-19 |
| JP2024009130A5 true JP2024009130A5 (https=) | 2024-06-24 |
Family
ID=67988017
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020550177A Active JP7406809B2 (ja) | 2018-03-20 | 2019-03-20 | 活力のある歯髄の再生 |
| JP2023196673A Pending JP2024009130A (ja) | 2018-03-20 | 2023-11-20 | 活力のある歯髄の再生 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020550177A Active JP7406809B2 (ja) | 2018-03-20 | 2019-03-20 | 活力のある歯髄の再生 |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US12285545B2 (https=) |
| EP (1) | EP3768222B1 (https=) |
| JP (2) | JP7406809B2 (https=) |
| WO (1) | WO2019183201A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019183201A1 (en) * | 2018-03-20 | 2019-09-26 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Regeneration of vital tooth pulp |
| WO2019241577A1 (en) | 2018-06-13 | 2019-12-19 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Bone regeneration in compromised wounds |
| US20220347347A1 (en) * | 2021-04-28 | 2022-11-03 | Worcester Polytechnic Institute | Ligament Repair Scaffold |
| US11890154B2 (en) * | 2021-06-30 | 2024-02-06 | Khalid AL HEZAIMI | Pulp capping methods |
| US20230166006A1 (en) * | 2021-12-01 | 2023-06-01 | Khalid Alhezaimi | Methods and compositions for periapical tissue regeneration |
Family Cites Families (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6632457B1 (en) | 1998-08-14 | 2003-10-14 | Incept Llc | Composite hydrogel drug delivery systems |
| US7206638B2 (en) | 2002-11-20 | 2007-04-17 | The Nemours Foundation | Electrical current induced inhibition of bone growth |
| CN1871024B (zh) * | 2003-09-09 | 2012-03-28 | 智再如股份有限公司 | 牙周病和牙髓疾病的治疗剂以及治疗方法 |
| US7901461B2 (en) | 2003-12-05 | 2011-03-08 | Ethicon, Inc. | Viable tissue repair implants and methods of use |
| AU2004309083B2 (en) * | 2003-12-30 | 2010-11-11 | Augustinus Bader | Tissue regeneration method |
| JP2005211477A (ja) | 2004-01-30 | 2005-08-11 | Gunze Ltd | 再生医療用支持体 |
| JP2005213449A (ja) | 2004-01-30 | 2005-08-11 | Gunze Ltd | ゼラチンスポンジ |
| US7680542B2 (en) | 2004-05-17 | 2010-03-16 | New York Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery | Radiofrequency ablation epiphysiodesis |
| JP2008517660A (ja) | 2004-10-22 | 2008-05-29 | ザ ボード オブ トラスティーズ オブ ザ ユニバーシティ オブ イリノイ | 生物剤を送達する中空かつ多孔質の整形外科用または歯科用のインプラント |
| US8268344B2 (en) | 2005-04-27 | 2012-09-18 | The Regents Of The University Of Michigan | Particle-containing complex porous materials |
| US20090148486A1 (en) | 2005-04-28 | 2009-06-11 | Helen Lu | Compositions and methods for treating pulp inflammations caused by infection or trauma |
| US20070286880A1 (en) | 2006-06-08 | 2007-12-13 | Andrey Vasiliev | Inoculated spongiform scaffold for transplantation and tissue regeneration |
| US20140302111A1 (en) * | 2007-10-25 | 2014-10-09 | The Trustees Of Columbia University In The City Of New York | Compositions and methods for dental tissue regeneration |
| EP2268254A4 (en) * | 2007-12-14 | 2013-12-11 | Univ Nova Southeastern | METHOD AND KIT FOR THE ADMINISTRATION OF REGENERATIVE ENDODONTIC TREATMENT |
| FR2926024B1 (fr) | 2008-01-07 | 2010-04-09 | Teknimed | Biomateriau pour osteosynthese |
| US8920791B2 (en) | 2008-03-12 | 2014-12-30 | Japan Health Sciences Foundation | Root canal filler and dental tissue regeneration method |
| ES2658609T3 (es) * | 2008-09-02 | 2018-03-12 | Tautona Group Lp | Hilos de ácido hialurónico y/o derivados de los mismos, métodos para fabricar los mismos, y usos de los mismos |
| EP2442834A2 (en) | 2009-06-15 | 2012-04-25 | Technion Research and Development Foundation, Ltd. | Reinforced surgical adhesives and sealants and their in-situ application |
| WO2010148229A1 (en) | 2009-06-17 | 2010-12-23 | The Trustees Of Columbia University In The City Of New York | Tooth scaffolds |
| US20120164604A1 (en) * | 2009-09-11 | 2012-06-28 | National Center For Geriatrics And Gerontology | Unextracted tooth root canal filler and dental tissue regeneration method for unextracted tooth |
| US9040070B2 (en) | 2009-10-20 | 2015-05-26 | Nitto Denko Corporation | Material for induction of hard tissue regeneration |
| US9327015B2 (en) | 2009-10-23 | 2016-05-03 | DePuy Synthes Products, Inc. | Methods and devices for correcting spinal deformity with pharmaceutical-eluting pedicle screws |
| US20130052155A1 (en) | 2009-11-09 | 2013-02-28 | Drexel University | Compositions and Methods for Treating a Disorder or Defect in Soft Tissue |
| US9180166B2 (en) | 2010-03-12 | 2015-11-10 | New Jersey Institute Of Technology | Cartilage repair systems and applications utilizing a glycosaminoglycan mimic |
| WO2011158245A1 (en) | 2010-06-16 | 2011-12-22 | Department Of Biotechnology | Sealbio: a novel non-obturation regenerative technique of endodontic treatment. |
| US20140050773A1 (en) | 2010-11-26 | 2014-02-20 | Universite De Strasbourg | Compound comprising alpha-msh for use in endodontic regeneration |
| US9051549B2 (en) * | 2011-02-22 | 2015-06-09 | Scripps Health | In situ tissue engineering using magnetically guided three dimensional cell patterning |
| EP2801377B1 (en) | 2011-03-04 | 2019-08-07 | The Regents of The University of California | Hydrogel comprising cells for local release of growth factors to mediate motor recovery after stroke |
| EP2508212A1 (en) | 2011-04-05 | 2012-10-10 | Universitätsklinikum Freiburg | Biocompatible and biodegradable gradient layer system for regenerative medicine and for tissue support |
| DK2854883T3 (da) | 2012-05-17 | 2019-07-15 | Cartiheal 2009 Ltd | Biomatrix-hydrogeler og fremgangsmåder til anvendelse deraf |
| EP2983643A4 (en) * | 2013-04-12 | 2016-12-28 | Univ Columbia | PROCESS FOR HOST CELL HOMING AND TOOTH MARK GENERATION |
| WO2014169236A1 (en) | 2013-04-12 | 2014-10-16 | The Trustees Of Columbia University In The City Of New York | Scaffolds for promoting calcified cartilage and/or bone formation |
| WO2015002707A1 (en) | 2013-05-28 | 2015-01-08 | The Johns Hopkins University | Bone regeneration using stromal vascular fraction. platelet-derived growth factor-rich hydrogel, three dimensional printed poly-epsilon-caprolactone scaffolds |
| US10335515B2 (en) | 2013-09-25 | 2019-07-02 | The University Of Kansas | Hydrogel precursors having nanoparticles |
| JP6644709B2 (ja) | 2014-04-29 | 2020-02-12 | デンツプライ シロナ インコーポレーテッド | 長期間薬物送達システムによる歯内療法 |
| WO2016011039A1 (en) | 2014-07-14 | 2016-01-21 | Temple University-Of The Commonwealth System Of Higher Education | Biomimetic scaffold for regenerative dentistry |
| CN104307049B (zh) | 2014-09-29 | 2016-04-13 | 四川大学华西医院 | 一种仿细胞外基质可注射的原位水凝胶及其制备方法与应用 |
| CN104548212B (zh) * | 2014-12-31 | 2018-05-11 | 新科沃再生医学（苏州）有限公司 | 一种促进牙髓及牙本质再生的组合物 |
| US11583613B2 (en) | 2016-03-03 | 2023-02-21 | University of Pittsburgh—of the Commonwealth System of Higher Education | Hydrogel systems for skeletal interfacial tissue regeneration applied to epiphyseal growth plate repair |
| US11278474B2 (en) * | 2016-12-01 | 2022-03-22 | Trustees Of Tufts College | Pulp regeneration compositions and methods of forming and using the same |
| US11701453B2 (en) * | 2017-05-30 | 2023-07-18 | Oregon Health & Science University | Dental pulp construct |
| TWI644801B (zh) | 2017-08-10 | 2018-12-21 | 國立清華大學 | 可積層製造的生物可降解光聚合高分子複合材料及其應用 |
| CL2017002194A1 (es) | 2017-08-29 | 2019-04-22 | Univ Pontificia Catolica Chile | Biomaterial particulado que contiene partículas con formas geodésicas, método de obtención y uso para relleno o substitución de tejido óseo |
| US11298441B2 (en) | 2017-11-08 | 2022-04-12 | The Regents Of The University Of Colorado, A Body Corporate | Biodegradable biomimetics of growth plate cartilage for the treatment of physeal injuries |
| WO2019183201A1 (en) | 2018-03-20 | 2019-09-26 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Regeneration of vital tooth pulp |
| WO2019241577A1 (en) | 2018-06-13 | 2019-12-19 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Bone regeneration in compromised wounds |
-
2019
- 2019-03-20 WO PCT/US2019/023132 patent/WO2019183201A1/en not_active Ceased
- 2019-03-20 US US16/979,038 patent/US12285545B2/en active Active
- 2019-03-20 EP EP19771745.7A patent/EP3768222B1/en active Active
- 2019-03-20 JP JP2020550177A patent/JP7406809B2/ja active Active
-
2023
- 2023-11-20 JP JP2023196673A patent/JP2024009130A/ja active Pending
-
2025
- 2025-03-19 US US19/084,682 patent/US20250242082A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2024009130A5 (https=) | ||
| Li et al. | Dental pulp regeneration strategies: A review of status quo and recent advances | |
| US5567806A (en) | Collagen crosslinked with a crosslinking agent for the manufacture of a suturable, biocompatible slowresorbing membrane, and such a membrane | |
| Giannobile et al. | Are dental implants a panacea or should we better strive to save teeth | |
| US8602783B2 (en) | Impression gingival cuff for dental implants | |
| Patras et al. | Management of provisional restorations' deficiencies: a literature review | |
| Mittal et al. | Regenerative evaluation of immature roots using PRF and artificial scaffolds in necrotic permanent teeth: a clinical study | |
| Fava | Acute apical periodontitis: incidence of post‐operative pain using two different root canal dressings | |
| JP2021518203A5 (https=) | ||
| Abramson et al. | Surgical approach to a severe case of sodium hypochlorite accident: a case report and review of the literature. | |
| Sheehy et al. | Advances in tissue engineering strategies for periodontal and endodontic regeneration: Current therapies and future trends for disease treatment and tissue repair in the oral cavity | |
| CN206659945U (zh) | 一种新型种植牙 | |
| August | Managing the abscessed open tooth: instrument and close—part 2 | |
| CA2852722C (en) | Impression gingival cuff for dental implants | |
| RU2619874C1 (ru) | Устройство для гальванофоретического очищения и таргетной наноимпрегнации корней зубов | |
| RU2238698C1 (ru) | Способ реставрации передних групп зубов с помощью армирующего сеточно-адгезивного штифта | |
| US10987197B2 (en) | Intraradicular anchor pin | |
| RU106524U1 (ru) | Неметаллическая культевая штифтовая вкладка | |
| Saini et al. | Esthetic rehabilitation of mutilated anterior teeth with custom cast post and core porcelain-fused-to-metal crowns | |
| CN221830834U (zh) | 一种用于口腔种植的可降解口腔膜钉 | |
| 杜裕康 et al. | Use of Periodontal Regeneration and Root Canal Therapy for the Treatment of Periodontally Poor or Hopeless Teeth: Report of Three Cases | |
| CN214966979U (zh) | 一种便于清理的二氧化锆全瓷义齿 | |
| Ahmed et al. | The Use of Hyaluronic Acid in Reducing Postoperative Complications in Minor Oral Surgery: A Review | |
| RU2231330C1 (ru) | Способ восстановления депульпированных малых и больших коренных зубов при тотальном разрушении коронок | |
| Kasraie et al. | Effect of bromelain and trypsin on microleakage of etch-and-rinse adhesive systems |