JP2024002985A5 - - Google Patents

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Publication number
JP2024002985A5
JP2024002985A5 JP2023103614A JP2023103614A JP2024002985A5 JP 2024002985 A5 JP2024002985 A5 JP 2024002985A5 JP 2023103614 A JP2023103614 A JP 2023103614A JP 2023103614 A JP2023103614 A JP 2023103614A JP 2024002985 A5 JP2024002985 A5 JP 2024002985A5
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JP
Japan
Prior art keywords
oligonucleotide
positions
rnai oligonucleotide
nucleotides
rnai
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2023103614A
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English (en)
Japanese (ja)
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JP2024002985A (ja
JP7560616B2 (ja
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Publication of JP2024002985A publication Critical patent/JP2024002985A/ja
Publication of JP2024002985A5 publication Critical patent/JP2024002985A5/ja
Application granted granted Critical
Publication of JP7560616B2 publication Critical patent/JP7560616B2/ja
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JP2023103614A 2022-06-24 2023-06-23 膜貫通型セリンプロテアーゼ6(tmprss6)発現を阻害するための組成物および方法 Active JP7560616B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US202263355210P 2022-06-24 2022-06-24
US63/355,210 2022-06-24
EP22209113 2022-11-23
EP22209113 2022-11-23

Publications (3)

Publication Number Publication Date
JP2024002985A JP2024002985A (ja) 2024-01-11
JP2024002985A5 true JP2024002985A5 (https=) 2024-03-22
JP7560616B2 JP7560616B2 (ja) 2024-10-02

Family

ID=87036742

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023103614A Active JP7560616B2 (ja) 2022-06-24 2023-06-23 膜貫通型セリンプロテアーゼ6(tmprss6)発現を阻害するための組成物および方法

Country Status (14)

Country Link
US (2) US11952574B2 (https=)
EP (1) EP4544049A1 (https=)
JP (1) JP7560616B2 (https=)
KR (1) KR102759742B1 (https=)
CN (1) CN119403927A (https=)
AR (1) AR129710A1 (https=)
AU (1) AU2023288906A1 (https=)
CA (1) CA3257962A1 (https=)
CO (1) CO2024017422A2 (https=)
IL (1) IL317012A (https=)
MA (1) MA71238A (https=)
MX (1) MX2024015763A (https=)
TW (1) TWI868755B (https=)
WO (1) WO2023247738A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI868755B (zh) 2022-06-24 2025-01-01 丹麥商諾佛 儂迪克股份有限公司 抑制跨膜絲胺酸蛋白酶6(tmprss6)表現的組成物及方法
WO2025148896A1 (en) * 2024-01-08 2025-07-17 Shanghai Argo Biopharmaceutical Co., Ltd. Compositions and methods for inhibiting expression of transmembrane serine protease 6 (tmprss6)
WO2026003163A1 (en) * 2024-06-26 2026-01-02 Silence Therapeutics Gmbh Sirna against tmprss6 for treating polycythemia vera

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US5889136A (en) 1995-06-09 1999-03-30 The Regents Of The University Of Colorado Orthoester protecting groups in RNA synthesis
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CA2429814C (en) 2000-12-01 2014-02-18 Thomas Tuschl Rna interference mediating small rna molecules
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US20070265220A1 (en) 2004-03-15 2007-11-15 City Of Hope Methods and compositions for the specific inhibition of gene expression by double-stranded RNA
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DK2341943T3 (en) 2008-09-22 2019-02-25 Dicerna Pharmaceuticals Inc COMPOSITIONS AND METHODS OF SPECIFIC INHIBITION OF DSRNA REPRINT WITH MODIFICATIONS
US20100249214A1 (en) 2009-02-11 2010-09-30 Dicerna Pharmaceuticals Multiplex dicer substrate rna interference molecules having joining sequences
KR101728655B1 (ko) 2008-12-18 2017-04-19 다이서나 파마수이티컬, 인크. 유전자 발현의 특이적 억제를 위한 연장된 다이서 기질 제제 및 방법
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WO2016085852A1 (en) 2014-11-24 2016-06-02 Alnylam Pharmaceuticals, Inc. Tmprss6 irna compositions and methods of use thereof
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EP4330392A1 (en) 2021-04-26 2024-03-06 Alnylam Pharmaceuticals, Inc. Transmembrane protease, serine 6 (tmprss6) irna compositions and methods of use thereof
TWI868755B (zh) 2022-06-24 2025-01-01 丹麥商諾佛 儂迪克股份有限公司 抑制跨膜絲胺酸蛋白酶6(tmprss6)表現的組成物及方法

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