JP2023553253A - 重水素化ｊａｋ阻害剤による脱毛障害の治療のためのレジメン - Google Patents

重水素化ｊａｋ阻害剤による脱毛障害の治療のためのレジメン Download PDF

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JP2023553253A
JP2023553253A JP2023526173A JP2023526173A JP2023553253A JP 2023553253 A JP2023553253 A JP 2023553253A JP 2023526173 A JP2023526173 A JP 2023526173A JP 2023526173 A JP2023526173 A JP 2023526173A JP 2023553253 A JP2023553253 A JP 2023553253A
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JP2023553253A5 (https=
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カセラ，ジェームズ・ヴィ．
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サン ファーマシューティカル インダストリーズ，インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2023526173A 2020-10-28 2021-10-28 重水素化ｊａｋ阻害剤による脱毛障害の治療のためのレジメン Pending JP2023553253A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063106790P 2020-10-28 2020-10-28
US63/106,790 2020-10-28
US202163155637P 2021-03-02 2021-03-02
US63/155,637 2021-03-02
PCT/US2021/057123 WO2022094133A1 (en) 2020-10-28 2021-10-28 Regimens for the treatment of hair loss disorders with deuterated jak inhibitors

Publications (2)

Publication Number Publication Date
JP2023553253A true JP2023553253A (ja) 2023-12-21
JP2023553253A5 JP2023553253A5 (https=) 2024-11-01

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JP2023526173A Pending JP2023553253A (ja) 2020-10-28 2021-10-28 重水素化ｊａｋ阻害剤による脱毛障害の治療のためのレジメン

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US (1) US20230390292A1 (https=)
EP (1) EP4236956A1 (https=)
JP (1) JP2023553253A (https=)
KR (1) KR20230093504A (https=)
AU (1) AU2021372512A1 (https=)
CA (1) CA3196551A1 (https=)
CL (1) CL2023001201A1 (https=)
CO (1) CO2023006808A2 (https=)
DO (1) DOP2023000085A (https=)
IL (1) IL302401A (https=)
JO (1) JOP20230090A1 (https=)
MX (1) MX2023005027A (https=)
PE (1) PE20231945A1 (https=)
WO (1) WO2022094133A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3250876A1 (en) * 2022-05-04 2023-11-09 Sun Pharmaceutical Industries, Inc. DOSAGE REGIMEN FOR TREATMENT WITH DEUTERATED JAK INHIBITORS
US12364699B2 (en) * 2023-10-10 2025-07-22 Sun Pharmaceuticals Industries, Inc. Method of treating hair loss disorders
US12247034B1 (en) * 2024-04-19 2025-03-11 Sun Pharmaceutical Industries, Inc. Crystalline form of deuruxolitinib phosphate

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019516684A (ja) * 2016-05-04 2019-06-20 コンサート ファーマシューティカルズ インコーポレイテッド 重水素化ｊａｋ阻害剤による脱毛障害の処置

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9925962D0 (en) 1999-11-02 1999-12-29 Novartis Ag Organic compounds
CN1255185C (zh) 2001-05-03 2006-05-10 弗·哈夫曼-拉罗切有限公司 无定形甲磺酸奈非那韦的药物剂型
MX2007003731A (es) 2004-09-29 2007-08-14 Johnson & Johnson Formas de dosis farmaceuticas de compuestos similares a rapamicina amorfos estables.
WO2007079139A2 (en) 2005-12-28 2007-07-12 Vertex Pharmaceuticals, Inc. Solid forms of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide
TWI720517B (zh) 2009-01-15 2021-03-01 美商英塞特公司 製造ｊａｋ抑制劑之方法及相關中間化合物
HRP20250965T1 (hr) 2012-06-15 2025-10-10 Sun Pharmaceutical Industries, Inc. Deuterirani derivati ruksolitiniba
AU2020219797B2 (en) 2019-02-06 2025-10-16 Sun Pharmaceutical Industries, Inc. Process for preparing enantiomerically enriched jak inhibitors
CA3228505A1 (en) * 2021-08-11 2023-02-16 Sun Pharmaceutical Industries, Inc. Treatment of hair loss disorders with deuterated jak inhibitors
US12364699B2 (en) * 2023-10-10 2025-07-22 Sun Pharmaceuticals Industries, Inc. Method of treating hair loss disorders

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019516684A (ja) * 2016-05-04 2019-06-20 コンサート ファーマシューティカルズ インコーポレイテッド 重水素化ｊａｋ阻害剤による脱毛障害の処置

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
OLSEN, E. A. ET AL.: "Ruxolitinib cream for the treatment of patients with alopecia areata: A 2-part, double-blind, random", JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, vol. 82, no. 2, JPN6025045027, 2019, pages 412 - 419, ISSN: 0005722985 *
ROSMARIN, D. ET AL.: "Ruxolitinib cream for treatment of vitiligo: a randomised, controlled, phase 2 trial", THE LANCET, vol. 396, JPN6025045026, 2020, pages 110 - 120, ISSN: 0005722986 *

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Publication number Publication date
CL2023001201A1 (es) 2023-11-17
US20230390292A1 (en) 2023-12-07
JOP20230090A1 (ar) 2023-04-27
MX2023005027A (es) 2023-07-31
CA3196551A1 (en) 2022-05-05
IL302401A (en) 2023-06-01
PE20231945A1 (es) 2023-12-05
AU2021372512A1 (en) 2023-06-22
KR20230093504A (ko) 2023-06-27
EP4236956A1 (en) 2023-09-06
CO2023006808A2 (es) 2023-09-08
WO2022094133A9 (en) 2023-05-19
WO2022094133A1 (en) 2022-05-05
DOP2023000085A (es) 2023-07-31

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