KR20230093504A - 중수소화된 jak 억제제를 이용한 탈모 장애의 치료를 위한 요법 - Google Patents

중수소화된 jak 억제제를 이용한 탈모 장애의 치료를 위한 요법 Download PDF

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Publication number
KR20230093504A
KR20230093504A KR1020237017998A KR20237017998A KR20230093504A KR 20230093504 A KR20230093504 A KR 20230093504A KR 1020237017998 A KR1020237017998 A KR 1020237017998A KR 20237017998 A KR20237017998 A KR 20237017998A KR 20230093504 A KR20230093504 A KR 20230093504A
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KR
South Korea
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compound
period
day
administered
pharmaceutically acceptable
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Pending
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KR1020237017998A
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English (en)
Korean (ko)
Inventor
제임스 브이. 카셀라
Original Assignee
썬 파마슈티칼 인더스트리즈 인코포레이티드
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Publication of KR20230093504A publication Critical patent/KR20230093504A/ko
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020237017998A 2020-10-28 2021-10-28 중수소화된 jak 억제제를 이용한 탈모 장애의 치료를 위한 요법 Pending KR20230093504A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063106790P 2020-10-28 2020-10-28
US63/106,790 2020-10-28
US202163155637P 2021-03-02 2021-03-02
US63/155,637 2021-03-02
PCT/US2021/057123 WO2022094133A1 (en) 2020-10-28 2021-10-28 Regimens for the treatment of hair loss disorders with deuterated jak inhibitors

Publications (1)

Publication Number Publication Date
KR20230093504A true KR20230093504A (ko) 2023-06-27

Family

ID=78725692

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020237017998A Pending KR20230093504A (ko) 2020-10-28 2021-10-28 중수소화된 jak 억제제를 이용한 탈모 장애의 치료를 위한 요법

Country Status (14)

Country Link
US (1) US20230390292A1 (https=)
EP (1) EP4236956A1 (https=)
JP (1) JP2023553253A (https=)
KR (1) KR20230093504A (https=)
AU (1) AU2021372512A1 (https=)
CA (1) CA3196551A1 (https=)
CL (1) CL2023001201A1 (https=)
CO (1) CO2023006808A2 (https=)
DO (1) DOP2023000085A (https=)
IL (1) IL302401A (https=)
JO (1) JOP20230090A1 (https=)
MX (1) MX2023005027A (https=)
PE (1) PE20231945A1 (https=)
WO (1) WO2022094133A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3250876A1 (en) * 2022-05-04 2023-11-09 Sun Pharmaceutical Industries, Inc. DOSAGE REGIMEN FOR TREATMENT WITH DEUTERATED JAK INHIBITORS
US12364699B2 (en) * 2023-10-10 2025-07-22 Sun Pharmaceuticals Industries, Inc. Method of treating hair loss disorders
US12247034B1 (en) * 2024-04-19 2025-03-11 Sun Pharmaceutical Industries, Inc. Crystalline form of deuruxolitinib phosphate

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9925962D0 (en) 1999-11-02 1999-12-29 Novartis Ag Organic compounds
CN1255185C (zh) 2001-05-03 2006-05-10 弗·哈夫曼-拉罗切有限公司 无定形甲磺酸奈非那韦的药物剂型
MX2007003731A (es) 2004-09-29 2007-08-14 Johnson & Johnson Formas de dosis farmaceuticas de compuestos similares a rapamicina amorfos estables.
WO2007079139A2 (en) 2005-12-28 2007-07-12 Vertex Pharmaceuticals, Inc. Solid forms of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide
TWI720517B (zh) 2009-01-15 2021-03-01 美商英塞特公司 製造ｊａｋ抑制劑之方法及相關中間化合物
HRP20250965T1 (hr) 2012-06-15 2025-10-10 Sun Pharmaceutical Industries, Inc. Deuterirani derivati ruksolitiniba
ES2988629T3 (es) * 2016-05-04 2024-11-21 Sun Pharmaceutical Ind Inc Tratamiento de trastornos de pérdida de cabello con inhibidores de JAK deuterados
AU2020219797B2 (en) 2019-02-06 2025-10-16 Sun Pharmaceutical Industries, Inc. Process for preparing enantiomerically enriched jak inhibitors
CA3228505A1 (en) * 2021-08-11 2023-02-16 Sun Pharmaceutical Industries, Inc. Treatment of hair loss disorders with deuterated jak inhibitors
US12364699B2 (en) * 2023-10-10 2025-07-22 Sun Pharmaceuticals Industries, Inc. Method of treating hair loss disorders

Also Published As

Publication number Publication date
CL2023001201A1 (es) 2023-11-17
US20230390292A1 (en) 2023-12-07
JOP20230090A1 (ar) 2023-04-27
MX2023005027A (es) 2023-07-31
CA3196551A1 (en) 2022-05-05
IL302401A (en) 2023-06-01
PE20231945A1 (es) 2023-12-05
AU2021372512A1 (en) 2023-06-22
JP2023553253A (ja) 2023-12-21
EP4236956A1 (en) 2023-09-06
CO2023006808A2 (es) 2023-09-08
WO2022094133A9 (en) 2023-05-19
WO2022094133A1 (en) 2022-05-05
DOP2023000085A (es) 2023-07-31

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PA0105 International application

Patent event date: 20230526

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20241028

Comment text: Request for Examination of Application