JP2023552936A - 核酸配列決定のための方法及び組成物 - Google Patents
核酸配列決定のための方法及び組成物 Download PDFInfo
- Publication number
- JP2023552936A JP2023552936A JP2022580798A JP2022580798A JP2023552936A JP 2023552936 A JP2023552936 A JP 2023552936A JP 2022580798 A JP2022580798 A JP 2022580798A JP 2022580798 A JP2022580798 A JP 2022580798A JP 2023552936 A JP2023552936 A JP 2023552936A
- Authority
- JP
- Japan
- Prior art keywords
- type
- nucleotide
- light source
- detectable
- excitation light
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/103—Nucleic acid detection characterized by the use of physical, structural and functional properties luminescence
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/131—Nucleic acid detection characterized by the use of physical, structural and functional properties the label being a member of a cognate binding pair, i.e. extends to antibodies, haptens, avidin
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063129137P | 2020-12-22 | 2020-12-22 | |
| US63/129,137 | 2020-12-22 | ||
| PCT/EP2021/087044 WO2022136402A1 (en) | 2020-12-22 | 2021-12-21 | Methods and compositions for nucleic acid sequencing |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023552936A true JP2023552936A (ja) | 2023-12-20 |
| JP2023552936A5 JP2023552936A5 (enExample) | 2025-01-06 |
Family
ID=79686924
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022580798A Pending JP2023552936A (ja) | 2020-12-22 | 2021-12-21 | 核酸配列決定のための方法及び組成物 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20220195518A1 (enExample) |
| EP (1) | EP4267765A1 (enExample) |
| JP (1) | JP2023552936A (enExample) |
| KR (1) | KR20230123871A (enExample) |
| CN (1) | CN115803458A (enExample) |
| AU (1) | AU2021406375A1 (enExample) |
| CA (1) | CA3182311A1 (enExample) |
| WO (1) | WO2022136402A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN119301275A (zh) * | 2022-05-31 | 2025-01-10 | 伊路米纳有限公司 | 用于核酸测序的组合物和方法 |
| WO2024124008A2 (en) | 2022-12-07 | 2024-06-13 | Element Biosciences, Inc. | Cyanine derivatives and related uses |
| EP4689181A1 (en) * | 2023-03-30 | 2026-02-11 | Illumina, Inc. | Compositions and methods for nucleic acid sequencing |
| WO2024216159A1 (en) * | 2023-04-13 | 2024-10-17 | Esbiolab Llc | Methods and compositions for nucleic acid sequencing using labeled nucleotides |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20190264279A1 (en) * | 2011-09-23 | 2019-08-29 | Illumina, Inc. | Methods and compositions for nucleic acid sequencing |
| JP2020504074A (ja) * | 2016-12-22 | 2020-02-06 | イルミナ ケンブリッジ リミテッド | クマリン化合物および蛍光標識としてのそれらの使用 |
Family Cites Families (63)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8822228D0 (en) | 1988-09-21 | 1988-10-26 | Southern E M | Support-bound oligonucleotides |
| US5800992A (en) | 1989-06-07 | 1998-09-01 | Fodor; Stephen P.A. | Method of detecting nucleic acids |
| US6346413B1 (en) | 1989-06-07 | 2002-02-12 | Affymetrix, Inc. | Polymer arrays |
| DE3924454A1 (de) | 1989-07-24 | 1991-02-07 | Cornelis P Prof Dr Hollenberg | Die anwendung von dna und dna-technologie fuer die konstruktion von netzwerken zur verwendung in der chip-konstruktion und chip-produktion (dna chips) |
| US5302509A (en) | 1989-08-14 | 1994-04-12 | Beckman Instruments, Inc. | Method for sequencing polynucleotides |
| US5770358A (en) | 1991-09-18 | 1998-06-23 | Affymax Technologies N.V. | Tagged synthetic oligomer libraries |
| CA2124087C (en) | 1991-11-22 | 2002-10-01 | James L. Winkler | Combinatorial strategies for polymer synthesis |
| EP0675966B1 (en) | 1992-02-19 | 2004-10-06 | The Public Health Research Institute Of The City Of New York, Inc. | Novel oligonucleotide arrays and their use for sorting, isolating, sequencing, and manipulating nucleic acids |
| US5583211A (en) | 1992-10-29 | 1996-12-10 | Beckman Instruments, Inc. | Surface activated organic polymers useful for location - specific attachment of nucleic acids, peptides, proteins and oligosaccharides |
| WO1995011995A1 (en) | 1993-10-26 | 1995-05-04 | Affymax Technologies N.V. | Arrays of nucleic acid probes on biological chips |
| US5472672A (en) | 1993-10-22 | 1995-12-05 | The Board Of Trustees Of The Leland Stanford Junior University | Apparatus and method for polymer synthesis using arrays |
| US6156501A (en) | 1993-10-26 | 2000-12-05 | Affymetrix, Inc. | Arrays of modified nucleic acid probes and methods of use |
| US5429807A (en) | 1993-10-28 | 1995-07-04 | Beckman Instruments, Inc. | Method and apparatus for creating biopolymer arrays on a solid support surface |
| US5807522A (en) | 1994-06-17 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for fabricating microarrays of biological samples |
| US5846719A (en) | 1994-10-13 | 1998-12-08 | Lynx Therapeutics, Inc. | Oligonucleotide tags for sorting and identification |
| US5556752A (en) | 1994-10-24 | 1996-09-17 | Affymetrix, Inc. | Surface-bound, unimolecular, double-stranded DNA |
| US5624711A (en) | 1995-04-27 | 1997-04-29 | Affymax Technologies, N.V. | Derivatization of solid supports and methods for oligomer synthesis |
| US5545531A (en) | 1995-06-07 | 1996-08-13 | Affymax Technologies N.V. | Methods for making a device for concurrently processing multiple biological chip assays |
| WO1997014028A2 (en) | 1995-10-11 | 1997-04-17 | Luminex Corporation | Multiplexed analysis of clinical specimens apparatus and method |
| US5658734A (en) | 1995-10-17 | 1997-08-19 | International Business Machines Corporation | Process for synthesizing chemical compounds |
| US6458530B1 (en) | 1996-04-04 | 2002-10-01 | Affymetrix Inc. | Selecting tag nucleic acids |
| US6297006B1 (en) | 1997-01-16 | 2001-10-02 | Hyseq, Inc. | Methods for sequencing repetitive sequences and for determining the order of sequence subfragments |
| JP2002503954A (ja) | 1997-04-01 | 2002-02-05 | グラクソ、グループ、リミテッド | 核酸増幅法 |
| US6465178B2 (en) | 1997-09-30 | 2002-10-15 | Surmodics, Inc. | Target molecule attachment to surfaces |
| US6485944B1 (en) | 1997-10-10 | 2002-11-26 | President And Fellows Of Harvard College | Replica amplification of nucleic acid arrays |
| US6087102A (en) | 1998-01-07 | 2000-07-11 | Clontech Laboratories, Inc. | Polymeric arrays and methods for their use in binding assays |
| US6287776B1 (en) | 1998-02-02 | 2001-09-11 | Signature Bioscience, Inc. | Method for detecting and classifying nucleic acid hybridization |
| JP3944996B2 (ja) | 1998-03-05 | 2007-07-18 | 株式会社日立製作所 | Ｄｎａプローブアレー |
| US6031078A (en) | 1998-06-16 | 2000-02-29 | Millennium Pharmaceuticals, Inc. | MTbx protein and nucleic acid molecules and uses therefor |
| WO2000006770A1 (en) | 1998-07-30 | 2000-02-10 | Solexa Ltd. | Arrayed biomolecules and their use in sequencing |
| GB0002310D0 (en) | 2000-02-01 | 2000-03-22 | Solexa Ltd | Polynucleotide sequencing |
| AR021833A1 (es) | 1998-09-30 | 2002-08-07 | Applied Research Systems | Metodos de amplificacion y secuenciacion de acido nucleico |
| US6277628B1 (en) | 1998-10-02 | 2001-08-21 | Incyte Genomics, Inc. | Linear microarrays |
| US6391937B1 (en) | 1998-11-25 | 2002-05-21 | Motorola, Inc. | Polyacrylamide hydrogels and hydrogel arrays made from polyacrylamide reactive prepolymers |
| WO2000063437A2 (en) | 1999-04-20 | 2000-10-26 | Illumina, Inc. | Detection of nucleic acid reactions on bead arrays |
| US6664061B2 (en) | 1999-06-25 | 2003-12-16 | Amersham Biosciences Ab | Use and evaluation of a [2+2] photoaddition in immobilization of oligonucleotides on a three-dimensional hydrogel matrix |
| US6372813B1 (en) | 1999-06-25 | 2002-04-16 | Motorola | Methods and compositions for attachment of biomolecules to solid supports, hydrogels, and hydrogel arrays |
| US6770441B2 (en) | 2000-02-10 | 2004-08-03 | Illumina, Inc. | Array compositions and methods of making same |
| AU2001279244A1 (en) | 2000-08-09 | 2002-02-18 | Motorola, Inc. | The use and evaluation of a (2+2) photocycloaddition in immobilization of oligonucleotides on a three-dimensional hydrogel matrix |
| WO2004018497A2 (en) | 2002-08-23 | 2004-03-04 | Solexa Limited | Modified nucleotides for polynucleotide sequencing |
| PT3438116T (pt) | 2002-08-23 | 2021-03-23 | Illumina Cambridge Ltd | Nucleótidos identificados |
| GB0321306D0 (en) | 2003-09-11 | 2003-10-15 | Solexa Ltd | Modified polymerases for improved incorporation of nucleotide analogues |
| GB0326073D0 (en) | 2003-11-07 | 2003-12-10 | Solexa Ltd | Improvements in or relating to polynucleotide arrays |
| EP1701785A1 (en) | 2004-01-07 | 2006-09-20 | Solexa Ltd. | Modified molecular arrays |
| GB0427236D0 (en) * | 2004-12-13 | 2005-01-12 | Solexa Ltd | Improved method of nucleotide detection |
| EP1888743B1 (en) | 2005-05-10 | 2011-08-03 | Illumina Cambridge Limited | Improved polymerases |
| JPWO2008090760A1 (ja) * | 2007-01-26 | 2010-05-20 | コニカミノルタエムジー株式会社 | 蛍光検出装置、マイクロチップ、及び検査システム |
| EP2782916B1 (en) * | 2011-11-21 | 2018-02-28 | Promega Corporation | Carboxy x rhodamine analogs |
| US9012022B2 (en) | 2012-06-08 | 2015-04-21 | Illumina, Inc. | Polymer coatings |
| US20140065628A1 (en) * | 2012-08-28 | 2014-03-06 | Integenx Inc. | Methods and Devices for Multi-Color, Out-of-Phase Detection in Electrophoresis |
| WO2014139596A1 (en) | 2013-03-15 | 2014-09-18 | Illumina Cambridge Limited | Modified nucleosides or nucleotides |
| GB201414098D0 (en) | 2014-08-08 | 2014-09-24 | Illumina Cambridge Ltd | Modified nucleotide linkers |
| US20170240961A1 (en) * | 2016-02-23 | 2017-08-24 | Complete Genomics, Inc. | Affinity tag labeled nucleosides and uses |
| US10385214B2 (en) | 2016-09-30 | 2019-08-20 | Illumina Cambridge Limited | Fluorescent dyes and their uses as biomarkers |
| ES3026859T3 (en) * | 2017-01-04 | 2025-06-12 | Mgi Tech Co Ltd | Stepwise sequencing by non-labeled reversible terminators or natural nucleotides |
| GB201716931D0 (en) * | 2017-10-16 | 2017-11-29 | Illumina Cambridge Ltd | New fluorescent compounds and their use as biomarkers |
| EP3874036A1 (en) | 2018-10-31 | 2021-09-08 | Illumina, Inc. | Polymerases, compositions, and methods of use |
| CN113272448B (zh) * | 2018-11-09 | 2025-02-07 | 深圳华大智造科技股份有限公司 | 使用未标记的核苷酸进行大规模平行测序 |
| WO2020117968A2 (en) | 2018-12-05 | 2020-06-11 | Illumina, Inc. | Polymerases, compositions, and methods of use |
| US11293061B2 (en) | 2018-12-26 | 2022-04-05 | Illumina Cambridge Limited | Sequencing methods using nucleotides with 3′ AOM blocking group |
| CA3103636A1 (en) | 2019-03-01 | 2020-09-10 | Illumina Cambridge Limited | Tertiary amine substituted coumarin compounds and their uses as fluorescent labels |
| BR112020026528B1 (pt) | 2019-03-01 | 2024-02-15 | Illumina Cambridge Limited | Composto de cumarina substituído com amina exocíclica, nucleotídeo ou oligonucleotídeo, kit, método de sequenciamento e método para sintetizar o referido composto |
| JP2023510454A (ja) | 2019-11-27 | 2023-03-14 | イルミナ ケンブリッジ リミテッド | シクロオクタテトラエンを含有する色素及び組成物 |
-
2021
- 2021-12-20 US US17/555,945 patent/US20220195518A1/en active Pending
- 2021-12-21 EP EP21844256.4A patent/EP4267765A1/en active Pending
- 2021-12-21 CN CN202180046203.2A patent/CN115803458A/zh active Pending
- 2021-12-21 KR KR1020227045715A patent/KR20230123871A/ko active Pending
- 2021-12-21 CA CA3182311A patent/CA3182311A1/en active Pending
- 2021-12-21 JP JP2022580798A patent/JP2023552936A/ja active Pending
- 2021-12-21 AU AU2021406375A patent/AU2021406375A1/en active Pending
- 2021-12-21 WO PCT/EP2021/087044 patent/WO2022136402A1/en not_active Ceased
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20190264279A1 (en) * | 2011-09-23 | 2019-08-29 | Illumina, Inc. | Methods and compositions for nucleic acid sequencing |
| JP2020504074A (ja) * | 2016-12-22 | 2020-02-06 | イルミナ ケンブリッジ リミテッド | クマリン化合物および蛍光標識としてのそれらの使用 |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2021406375A1 (en) | 2023-01-05 |
| CA3182311A1 (en) | 2022-06-30 |
| KR20230123871A (ko) | 2023-08-24 |
| WO2022136402A1 (en) | 2022-06-30 |
| US20220195518A1 (en) | 2022-06-23 |
| EP4267765A1 (en) | 2023-11-01 |
| CN115803458A (zh) | 2023-03-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN115916908B (zh) | 长斯托克斯位移色烯并喹啉染料及其在测序应用中的用途 | |
| KR102053108B1 (ko) | 폴리메틴 화합물 및 형광 표지로서의 이의 용도 | |
| WO2023232829A1 (en) | Compositions and methods for nucleic acid sequencing | |
| JP2024516191A (ja) | ビス－ホウ素縮合複素環を含有する蛍光色素及び配列決定における使用 | |
| JP2023552936A (ja) | 核酸配列決定のための方法及び組成物 | |
| JP2018525322A (ja) | 長ストークスシフトを有するポリメチン化合物と、蛍光標識としてのその使用 | |
| CN115996937B (zh) | 烷基吡啶正离子香豆素染料和在测序应用中的用途 | |
| CN119604513A (zh) | 含有稠合四环双硼杂环的荧光染料及其在测序中的用途 | |
| AU2018298847A1 (en) | Short pendant arm linkers for nucleotides in sequencing applications | |
| JP2023552935A (ja) | 核酸配列決定のための方法、システム、及び組成物 | |
| CN112639128B (zh) | 利用光可切换标记进行核酸测序的方法和组合物 | |
| AU2023246851A1 (en) | Compositions and methods for improving sequencing signals | |
| US20230304086A1 (en) | Labeled avidin and methods for sequencing | |
| HK40020379A (en) | Polymethine compounds and their use as fluorescent labels | |
| HK40020379B (en) | Polymethine compounds and their use as fluorescent labels |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20241220 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20241220 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20251125 |
|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20251128 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20260225 |