JP2023552002A5 - - Google Patents
Info
- Publication number
- JP2023552002A5 JP2023552002A5 JP2023548534A JP2023548534A JP2023552002A5 JP 2023552002 A5 JP2023552002 A5 JP 2023552002A5 JP 2023548534 A JP2023548534 A JP 2023548534A JP 2023548534 A JP2023548534 A JP 2023548534A JP 2023552002 A5 JP2023552002 A5 JP 2023552002A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- alkyl
- compound according
- membered
- optionally substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063092768P | 2020-10-16 | 2020-10-16 | |
| US63/092,768 | 2020-10-16 | ||
| PCT/US2021/055173 WO2022081967A1 (en) | 2020-10-16 | 2021-10-15 | Malt1 modulators and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023552002A JP2023552002A (ja) | 2023-12-13 |
| JP2023552002A5 true JP2023552002A5 (https=) | 2024-09-13 |
| JP7818011B2 JP7818011B2 (ja) | 2026-02-19 |
Family
ID=81209361
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023548534A Active JP7818011B2 (ja) | 2020-10-16 | 2021-10-15 | Ｍａｌｔ１モジュレーターおよびその使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20230391781A1 (https=) |
| EP (1) | EP4228647A4 (https=) |
| JP (1) | JP7818011B2 (https=) |
| CN (1) | CN116916924B (https=) |
| AU (1) | AU2021361057A1 (https=) |
| CA (1) | CA3198715A1 (https=) |
| WO (1) | WO2022081967A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB202018412D0 (en) * | 2020-11-23 | 2021-01-06 | Exscientia Ltd | Malt-1 modulators ii |
| TW202345806A (zh) | 2022-03-31 | 2023-12-01 | 美商艾伯維有限公司 | 噻唑并〔５，４－ｂ〕吡啶ｍａｌｔ－１抑制劑 |
| EP4638458A1 (en) * | 2022-12-23 | 2025-10-29 | Janssen Pharmaceutica NV | Malt1 inhibitors |
| WO2024182599A2 (en) * | 2023-03-01 | 2024-09-06 | Rarefied Biosciences, Inc. | Compositions and methods for treating malt1 associated diseases |
| WO2025223516A1 (zh) * | 2024-04-24 | 2025-10-30 | 首药控股(北京)股份有限公司 | 一种抑制剂杂环化合物 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3845770A (en) | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
| US4326525A (en) | 1980-10-14 | 1982-04-27 | Alza Corporation | Osmotic device that improves delivery properties of agent in situ |
| US5364620A (en) | 1983-12-22 | 1994-11-15 | Elan Corporation, Plc | Controlled absorption diltiazem formulation for once daily administration |
| US5023252A (en) | 1985-12-04 | 1991-06-11 | Conrex Pharmaceutical Corporation | Transdermal and trans-membrane delivery of drugs |
| US5001139A (en) | 1987-06-12 | 1991-03-19 | American Cyanamid Company | Enchancers for the transdermal flux of nivadipine |
| US4992445A (en) | 1987-06-12 | 1991-02-12 | American Cyanamid Co. | Transdermal delivery of pharmaceuticals |
| US4902514A (en) | 1988-07-21 | 1990-02-20 | Alza Corporation | Dosage form for administering nilvadipine for treating cardiovascular symptoms |
| US5593996A (en) * | 1991-12-30 | 1997-01-14 | American Cyanamid Company | Triazolopyrimidine derivatives |
| EP1644003A1 (en) * | 2003-06-04 | 2006-04-12 | Vernalis (Cambridge) Limited | Triazolo ´1,5-a!pyrimidines and their use in medicine |
| WO2008065198A1 (en) * | 2006-12-01 | 2008-06-05 | Galapagos N.V. | Triazolopyridine compounds useful for the treatment of degenerative & inflammatory diseases |
| SG11201607895PA (en) * | 2014-05-28 | 2016-12-29 | Novartis Ag | Novel pyrazolo pyrimidine derivatives and their use as malt1 inhibitors |
| WO2017000277A1 (en) * | 2015-07-01 | 2017-01-05 | Merck Sharp & Dohme Corp. | Substituted triazolo bicycliccompounds as pde2 inhibitors |
| US10711036B2 (en) * | 2015-08-28 | 2020-07-14 | Cornell University | MALT1 inhibitors and uses thereof |
| PE20190656A1 (es) * | 2016-07-29 | 2019-05-08 | Lupin Ltd | Compuestos de tiazolo-piridina sustituida como inhibidores de malt1 |
| TWI795381B (zh) * | 2016-12-21 | 2023-03-11 | 比利時商健生藥品公司 | 作為ｍａｌｔ１抑制劑之吡唑衍生物 |
| EP3810609B1 (en) | 2018-06-18 | 2024-06-12 | Janssen Pharmaceutica NV | Pyrazole derivatives as malt1 inhibitors |
| TWI848400B (zh) * | 2018-11-28 | 2024-07-11 | 日商武田藥品工業股份有限公司 | 雜環化合物及醫藥 |
-
2021
- 2021-10-15 JP JP2023548534A patent/JP7818011B2/ja active Active
- 2021-10-15 CA CA3198715A patent/CA3198715A1/en active Pending
- 2021-10-15 WO PCT/US2021/055173 patent/WO2022081967A1/en not_active Ceased
- 2021-10-15 EP EP21881170.1A patent/EP4228647A4/en active Pending
- 2021-10-15 US US18/031,981 patent/US20230391781A1/en active Pending
- 2021-10-15 CN CN202180083881.6A patent/CN116916924B/zh active Active
- 2021-10-15 AU AU2021361057A patent/AU2021361057A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2023552002A5 (https=) | ||
| JP2023502441A5 (https=) | ||
| JP2019530699A5 (https=) | ||
| RU2013158933A (ru) | Новые модуляторы иммунной системы родственные заявки | |
| RU2019132666A (ru) | Макроциклические соединения в качестве ингибиторов киназы ros1 | |
| PE20212304A1 (es) | Inhibidores de il-17a imidazo[1,2-b]piridazin-2-il | |
| RU2015101106A (ru) | Способ лечения лимфомы, применяя тиенотриазолодиазепиновые соединения | |
| JP2018504437A5 (https=) | ||
| RU2010105678A (ru) | Гетероциклические амидные соединения как ингибиторы протеинкиназ | |
| IL272115B (en) | An aryl-phosphorus-oxygen compound as an egfr kinase inhibitor | |
| RU2007114293A (ru) | Диаминотриазольные соединения, применяемые в качестве ингибиторов протеиновой киназы | |
| JP2010504346A5 (https=) | ||
| JP2014500870A5 (https=) | ||
| RU2018138828A (ru) | Уменьшение массы опухоли путем введения ccr1 антагонистов в комбинации с pd-1 ингибиторами или pd-l1 ингибиторами | |
| RU2009105826A (ru) | 2,4-ди(ариламино)питимидин-5-карбоксамидные соединения в качестве ингибиторов jak-киназ | |
| JP2010504347A5 (https=) | ||
| JP2011046700A5 (https=) | ||
| JP2021522262A5 (https=) | ||
| RU2008122046A (ru) | Аминопиримидины в качестве ингибиторов киназ | |
| RU2014128307A (ru) | Пиррольное производное шестичленного гетероарильного кольца, способ его получения и его медицинское применение | |
| JP2022538917A5 (https=) | ||
| JP2013503139A5 (https=) | ||
| RU2013151803A (ru) | Бициклические гетероциклические соединения и их применения в терапии | |
| JP2016501185A5 (https=) | ||
| JP2023537271A5 (https=) |