JP2023550932A - アデノシンデアミナーゼ、並びに関連する生体材料及びその使用 - Google Patents
アデノシンデアミナーゼ、並びに関連する生体材料及びその使用 Download PDFInfo
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- JP2023550932A JP2023550932A JP2023530524A JP2023530524A JP2023550932A JP 2023550932 A JP2023550932 A JP 2023550932A JP 2023530524 A JP2023530524 A JP 2023530524A JP 2023530524 A JP2023530524 A JP 2023530524A JP 2023550932 A JP2023550932 A JP 2023550932A
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Images
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
- C12N15/8218—Antisense, co-suppression, viral induced gene silencing [VIGS], post-transcriptional induced gene silencing [PTGS]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/22—Ribonucleases RNAses, DNAses
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/09—Fusion polypeptide containing a localisation/targetting motif containing a nuclear localisation signal
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
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- Plant Pathology (AREA)
- Virology (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011308944.7A CN112126637B (zh) | 2020-11-20 | 2020-11-20 | 腺苷脱氨酶及其相关生物材料与应用 |
| CN202011308944.7 | 2020-11-20 | ||
| PCT/CN2021/098034 WO2022105190A1 (zh) | 2020-11-20 | 2021-06-03 | 腺苷脱氨酶及其相关生物材料与应用 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2023550932A true JP2023550932A (ja) | 2023-12-06 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023530524A Pending JP2023550932A (ja) | 2020-11-20 | 2021-06-03 | アデノシンデアミナーゼ、並びに関連する生体材料及びその使用 |
Country Status (4)
| Country | Link |
|---|---|
| JP (1) | JP2023550932A (zh) |
| KR (1) | KR20230135047A (zh) |
| CN (2) | CN112126637B (zh) |
| WO (1) | WO2022105190A1 (zh) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112126637B (zh) * | 2020-11-20 | 2021-02-09 | 中国农业科学院植物保护研究所 | 腺苷脱氨酶及其相关生物材料与应用 |
| CN113699135B (zh) * | 2021-08-10 | 2022-05-24 | 国家卫生健康委科学技术研究所 | 一种无pam限制的腺嘌呤碱基编辑器融合蛋白及应用 |
| CN114438110B (zh) * | 2022-01-25 | 2023-08-04 | 浙江大学杭州国际科创中心 | 一种精确无pam限制的腺嘌呤碱基编辑器及其构建方法 |
| WO2023163806A1 (en) * | 2022-02-22 | 2023-08-31 | Massachusetts Institute Of Technology | Engineered nucleases and methods of use thereof |
| CN114606227B (zh) * | 2022-02-22 | 2024-03-08 | 复旦大学 | 高精度腺嘌呤碱基编辑器及其应用 |
| WO2023187027A1 (en) * | 2022-03-30 | 2023-10-05 | BASF Agricultural Solutions Seed US LLC | Optimized base editors |
| CN115725533B (zh) * | 2022-11-18 | 2023-08-25 | 中国农业科学院作物科学研究所 | 一种获得抗草甘膦水稻的方法及其所用双碱基融合编辑系统 |
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| WO2019226953A1 (en) * | 2018-05-23 | 2019-11-28 | The Broad Institute, Inc. | Base editors and uses thereof |
| CN110607320B (zh) * | 2018-11-23 | 2023-05-12 | 电子科技大学 | 一种植物基因组定向碱基编辑骨架载体及其应用 |
| WO2020214842A1 (en) * | 2019-04-17 | 2020-10-22 | The Broad Institute, Inc. | Adenine base editors with reduced off-target effects |
| CN110029096B (zh) * | 2019-05-09 | 2023-05-12 | 上海科技大学 | 一种腺嘌呤碱基编辑工具及其用途 |
| CN112126637B (zh) * | 2020-11-20 | 2021-02-09 | 中国农业科学院植物保护研究所 | 腺苷脱氨酶及其相关生物材料与应用 |
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2020
- 2020-11-20 CN CN202011308944.7A patent/CN112126637B/zh active Active
- 2020-11-20 CN CN202110061201.2A patent/CN112852791B/zh active Active
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2021
- 2021-06-03 KR KR1020237020153A patent/KR20230135047A/ko unknown
- 2021-06-03 JP JP2023530524A patent/JP2023550932A/ja active Pending
- 2021-06-03 WO PCT/CN2021/098034 patent/WO2022105190A1/zh active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| WO2022105190A1 (zh) | 2022-05-27 |
| CN112852791A (zh) | 2021-05-28 |
| CN112126637B (zh) | 2021-02-09 |
| KR20230135047A (ko) | 2023-09-22 |
| CN112852791B (zh) | 2022-05-24 |
| CN112126637A (zh) | 2020-12-25 |
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