JP2023550419A5 - - Google Patents
Info
- Publication number
- JP2023550419A5 JP2023550419A5 JP2023530164A JP2023530164A JP2023550419A5 JP 2023550419 A5 JP2023550419 A5 JP 2023550419A5 JP 2023530164 A JP2023530164 A JP 2023530164A JP 2023530164 A JP2023530164 A JP 2023530164A JP 2023550419 A5 JP2023550419 A5 JP 2023550419A5
- Authority
- JP
- Japan
- Prior art keywords
- sequence
- seq
- chain variable
- group
- variable region
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNPCT/CN2020/129918 | 2020-11-18 | ||
| CN2020129918 | 2020-11-18 | ||
| CN2021073341 | 2021-01-22 | ||
| CNPCT/CN2021/073341 | 2021-01-22 | ||
| PCT/CN2021/131389 WO2022105817A1 (en) | 2020-11-18 | 2021-11-18 | Bi-functional molecules |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023550419A JP2023550419A (ja) | 2023-12-01 |
| JP2023550419A5 true JP2023550419A5 (enExample) | 2024-11-26 |
Family
ID=81708373
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023530164A Pending JP2023550419A (ja) | 2020-11-18 | 2021-11-18 | 二機能性分子 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20240043566A1 (enExample) |
| EP (1) | EP4247424A4 (enExample) |
| JP (1) | JP2023550419A (enExample) |
| KR (1) | KR20230110546A (enExample) |
| CN (1) | CN116390948A (enExample) |
| AU (1) | AU2021383879A1 (enExample) |
| CA (1) | CA3201518A1 (enExample) |
| TW (1) | TW202235104A (enExample) |
| WO (1) | WO2022105817A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3095675A1 (en) | 2020-10-07 | 2022-04-07 | Xbiotech Inc. | True human antibody specific for interleukin 1 alpha (il-1a) |
| CA3095676A1 (en) | 2020-10-07 | 2022-04-07 | Xbiotech Inc. | True human antibody specific for interleukin 1 alpha (il-1a) |
| CA3095740A1 (en) | 2020-10-07 | 2022-04-07 | Xbiotech Inc. | True human antibody specific for interleukin alpha (il-1a) |
| CA3095679A1 (en) * | 2020-10-07 | 2022-04-07 | Xbiotech Inc. | True human antibody specific for interleuken 1 alpha (il-1a) |
| US20250282874A1 (en) * | 2022-05-17 | 2025-09-11 | Suzhou Transcenta Therapeutics Co., Ltd. | Bifunctional protein, and preparation thereof and use thereof |
| EP4603512A4 (en) * | 2022-10-13 | 2025-12-10 | Dartsbio Pharmaceuticals Ltd | B7h3/pdl1 bispecific antibody, and pharmaceutical composition comprising same and use thereof |
| GB202402046D0 (en) * | 2024-02-14 | 2024-03-27 | Bivictrix Ltd | Therapeutic antibodies |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ517202A (en) * | 1999-08-24 | 2004-05-28 | Medarex Inc | Human CTLA-4 antibodies and their uses |
| CA2672229A1 (en) * | 2006-12-14 | 2008-06-19 | Actogenix N.V. | Delivery of binding molecules to induce immunomodulation |
| WO2011163452A2 (en) * | 2010-06-24 | 2011-12-29 | Eleven Biotherapeutics, Inc. | Treating surface of the eye disorders |
| US9682143B2 (en) * | 2012-08-14 | 2017-06-20 | Ibc Pharmaceuticals, Inc. | Combination therapy for inducing immune response to disease |
| ES2895848T3 (es) * | 2012-12-17 | 2022-02-22 | Cell Medica Inc | Anticuerpos contra IL-1 beta |
| US8877202B2 (en) * | 2013-02-07 | 2014-11-04 | Immunomedics, Inc. | Pro-drug form (P2PDOX) of the highly potent 2-pyrrolinodoxorubicin conjugated to antibodies for targeted therapy of cancer |
| CN108495651A (zh) * | 2015-12-17 | 2018-09-04 | 诺华股份有限公司 | 抗pd-1的抗体分子及其用途 |
| JP7080213B2 (ja) * | 2016-03-23 | 2022-06-03 | スーチョウ トランセンタ セラピューティクス カンパニー,リミテッド | 新規抗pd-l1抗体 |
| WO2018014260A1 (en) * | 2016-07-20 | 2018-01-25 | Nanjing Legend Biotech Co., Ltd. | Multispecific antigen binding proteins and methods of use thereof |
| CN108220228A (zh) * | 2016-12-09 | 2018-06-29 | 上海迈泰君奥生物技术有限公司 | 无血清细胞培养基及高效表达重组蛋白质的方法 |
| AU2018266103B2 (en) * | 2017-05-09 | 2024-06-13 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Combination PDL1 and TGF-beta blockade in patients with HPV+ malignancies |
| EP3947449A4 (en) * | 2019-04-01 | 2022-09-07 | Immetas Therapeutics, Inc. | BISPECIFIC BINDING MOLECULES THAT TARGET THE TUMORS MICROENVIRONMENT AND AN IMMUNE CHECKPOINT PROTEIN |
| CN111763261B (zh) * | 2019-04-02 | 2022-08-09 | 杭州尚健生物技术有限公司 | 一种融合蛋白及其用途 |
-
2021
- 2021-11-18 JP JP2023530164A patent/JP2023550419A/ja active Pending
- 2021-11-18 EP EP21893964.3A patent/EP4247424A4/en active Pending
- 2021-11-18 CA CA3201518A patent/CA3201518A1/en active Pending
- 2021-11-18 KR KR1020237020099A patent/KR20230110546A/ko active Pending
- 2021-11-18 AU AU2021383879A patent/AU2021383879A1/en active Pending
- 2021-11-18 US US18/253,398 patent/US20240043566A1/en active Pending
- 2021-11-18 WO PCT/CN2021/131389 patent/WO2022105817A1/en not_active Ceased
- 2021-11-18 TW TW110143071A patent/TW202235104A/zh unknown
- 2021-11-18 CN CN202180072768.8A patent/CN116390948A/zh active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR102607909B1 (ko) | 항-cd28 조성물 | |
| JP7846668B2 (ja) | リガンド-受容体対及び生物学的に機能的なタンパク質を含む融合タンパク質 | |
| CN116583298B (zh) | 具有改善的特性的PD-1靶向IL-15/IL-15Rα FC融合蛋白 | |
| JP6622396B2 (ja) | 多重特異性抗体プラットフォームおよびその関連方法 | |
| JP2021521275A5 (enExample) | ||
| WO2020023702A1 (en) | Novel il-21 prodrugs and methods of use thereof | |
| JP7737306B2 (ja) | T細胞に結合する多機能性分子および自己免疫障害を処置するためのその使用 | |
| JP2021525082A5 (enExample) | ||
| AU2019359475A1 (en) | PD-1 targeted IL-15/IL-15Ralpha Fc fusion proteins and uses in combination therapies thereof | |
| JP2021521779A (ja) | IL−15/IL−15RA Fc融合タンパク質およびLAG−3抗原結合ドメインを含む、LAG−3を標的とするヘテロ二量体融合タンパク質 | |
| JP2023159379A (ja) | Pd-1とvegfを標的とした四価二重特異性抗体、その製造方法および用途 | |
| US20240043566A1 (en) | Bi-functional molecules | |
| CN119365490A (zh) | 结合pd-l1、pd-l2和/或cd28的抗体 | |
| JP2023543896A5 (enExample) | ||
| US20220089722A1 (en) | Heterodimeric fusion protein | |
| JP2025503480A5 (enExample) | ||
| WO2025201240A1 (en) | Antibodies targeting cd3, cd28, and pd-l1 and uses thereof | |
| US20250282874A1 (en) | Bifunctional protein, and preparation thereof and use thereof | |
| RU2023101035A (ru) | Антитела к pd-1 и слитые белки | |
| HK40103881A (en) | Combination therapy of pd-1-targeted il-2 variant immunoconjugates and fap/4-1bb binding molecules | |
| RU2024117654A (ru) | Антитела к b7-h4 и слитые белки антитело к b7-h4/il-15 | |
| CN116547306A (zh) | 抗cd28和/或抗b7h3组合物 | |
| TH2101001840A (th) | แอนติบอดีสารต้าน hla-g, องค์ประกอบซึ่งประกอบรวมด้วยแอนติบอดีสารต้าน hla-g และวิธีของการใช้แอนติบอดีสารต้าน hla-g | |
| HK40094278B (en) | Fusion proteins comprising a ligand-receptor pair and a biologically functional protein |