JP2023549287A - 核酸検出及び疾患診断のための、質量分析に基づく方法及びキット - Google Patents

核酸検出及び疾患診断のための、質量分析に基づく方法及びキット Download PDF

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JP2023549287A
JP2023549287A JP2023548980A JP2023548980A JP2023549287A JP 2023549287 A JP2023549287 A JP 2023549287A JP 2023548980 A JP2023548980 A JP 2023548980A JP 2023548980 A JP2023548980 A JP 2023548980A JP 2023549287 A JP2023549287 A JP 2023549287A
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tag
seq
nucleic acid
detection
sequence
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ジー.マーシャル ジョン
ミャオ ミン
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ワイワイゼット ファーマテック インコーポレイティド
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • C12Q1/6825Nucleic acid detection involving sensors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6851Quantitative amplification
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2023548980A 2020-10-26 2021-10-26 核酸検出及び疾患診断のための、質量分析に基づく方法及びキット Pending JP2023549287A (ja)

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US202063105554P 2020-10-26 2020-10-26
US63/105,554 2020-10-26
PCT/CA2021/051510 WO2022087730A1 (en) 2020-10-26 2021-10-26 Mass spectrometry-based methods and kits for nucleic acid detection and disease diagnostic

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JP2023549287A true JP2023549287A (ja) 2023-11-22
JP2023549287A5 JP2023549287A5 (https=) 2024-10-24

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US (1) US20240011108A1 (https=)
EP (1) EP4232598A4 (https=)
JP (1) JP2023549287A (https=)
CN (1) CN116391047A (https=)
CA (1) CA3195481A1 (https=)
WO (1) WO2022087730A1 (https=)

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Publication number Priority date Publication date Assignee Title
WO2024182168A1 (en) * 2023-02-28 2024-09-06 The Regents Of The University Of California Biosensor materials
WO2025194322A1 (zh) * 2024-03-19 2025-09-25 深圳华大生命科学研究院 用于组织石蜡切片空间蛋白组学测序文库的构建方法和测序方法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002027993A (ja) * 2000-06-08 2002-01-29 Xiao Bing Wang 特定の核酸を検出定量するための等長プライマー伸長法およびキット
US6468748B1 (en) * 1996-03-04 2002-10-22 Sequenom, Inc. Methods of screening nucleic acids using volatile salts in mass spectrometry
JP2008154498A (ja) * 2006-12-22 2008-07-10 Osaka Industrial Promotion Organization Pcrにより増幅させた伸長dna鎖の検出方法、および、標的配列の測定方法
JP2012500394A (ja) * 2008-08-20 2012-01-05 アベシア・バイオテクノロジー・インコーポレーテッド オリゴヌクレオチドの分析法
WO2014186874A1 (en) * 2013-05-23 2014-11-27 Yyz Pharmatech, Inc. Methods and compositions for enzyme linked immuno and hybridization mass spectrometric assay

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6468748B1 (en) * 1996-03-04 2002-10-22 Sequenom, Inc. Methods of screening nucleic acids using volatile salts in mass spectrometry
JP2002027993A (ja) * 2000-06-08 2002-01-29 Xiao Bing Wang 特定の核酸を検出定量するための等長プライマー伸長法およびキット
JP2008154498A (ja) * 2006-12-22 2008-07-10 Osaka Industrial Promotion Organization Pcrにより増幅させた伸長dna鎖の検出方法、および、標的配列の測定方法
JP2012500394A (ja) * 2008-08-20 2012-01-05 アベシア・バイオテクノロジー・インコーポレーテッド オリゴヌクレオチドの分析法
WO2014186874A1 (en) * 2013-05-23 2014-11-27 Yyz Pharmatech, Inc. Methods and compositions for enzyme linked immuno and hybridization mass spectrometric assay

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BANERJEE, SHIBDAS ET AL.: "Electrospray Ionization Mass Spectrometry: A Technique to Access the Information beyond the Molecula", INTERNATIONAL JOURNAL OF ANALYTICAL CHEMISTRY, vol. 2012, JPN6025039927, 2012, pages 1 - 40, ISSN: 0005697667 *

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WO2022087730A1 (en) 2022-05-05
EP4232598A1 (en) 2023-08-30
CN116391047A (zh) 2023-07-04
US20240011108A1 (en) 2024-01-11
EP4232598A4 (en) 2024-10-23
CA3195481A1 (en) 2022-05-05

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