|
EP1978095A1
(en)
|
1993-02-12 |
2008-10-08 |
The Board Of Trustees Of The Leland Stanford Junior University |
Chimeric receptor proteins for controlling signal transduction and ligands binding thereto
|
|
ATE544776T1
(de)
|
1994-12-29 |
2012-02-15 |
Massachusetts Inst Technology |
Chimäre dna-bindeproteine
|
|
WO1996041865A1
(en)
|
1995-06-07 |
1996-12-27 |
Ariad Gene Therapeutics, Inc. |
Rapamcycin-based regulation of biological events
|
|
AU9036198A
(en)
|
1997-08-26 |
1999-03-16 |
Ariad Gene Therapeutics, Inc. |
Fusion proteins comprising a dimerization, trimerization or tetramerization domain and an additional heterologous transcription activation, transcription repression, dna binding or ligand binding domain
|
|
EP1003886A1
(en)
|
1997-08-27 |
2000-05-31 |
Ariad Gene Therapeutics, Inc. |
Chimeric transcriptional activators and compositions and uses related thereto
|
|
CA2318402A1
(en)
|
1998-01-15 |
1999-07-22 |
Ariad Gene Therapeutics, Inc. |
Regulation of biological events using multimeric chimeric proteins
|
|
EP1053241A1
(en)
|
1998-02-13 |
2000-11-22 |
President And Fellows Of Harvard College |
Novel dimerizing agents, their production and use
|
|
EP2369002A1
(en)
|
1999-08-09 |
2011-09-28 |
Targeted Genetics Corporation |
Enhancement of expression of a single-stranded, heterologous nucleotide sequence from recombinant viral vectors by designing the sequence such that it forms intrastrand base pairs
|
|
US7067526B1
(en)
|
1999-08-24 |
2006-06-27 |
Ariad Gene Therapeutics, Inc. |
28-epirapalogs
|
|
SG10202108118RA
(en)
|
2001-11-13 |
2021-08-30 |
Univ Pennsylvania |
A method of detecting and/or identifying adeno-associated virus (aav) sequences and isolating novel sequences identified thereby
|
|
ES2975413T3
(es)
|
2001-12-17 |
2024-07-05 |
Univ Pennsylvania |
Secuencias de serotipo 8 de virus adenoasociado (AAV), vectores que las contienen y usos de las mismas
|
|
US20090010920A1
(en)
|
2003-03-03 |
2009-01-08 |
Xencor, Inc. |
Fc Variants Having Decreased Affinity for FcyRIIb
|
|
US8399618B2
(en)
|
2004-10-21 |
2013-03-19 |
Xencor, Inc. |
Immunoglobulin insertions, deletions, and substitutions
|
|
HUE054805T2
(hu)
|
2003-09-30 |
2021-09-28 |
Univ Pennsylvania |
Adeno-asszociált vírus (AAV) kládok, szekvenciák, az azokat tartalmazó vektorok és alkalmazásaik
|
|
US20070135620A1
(en)
|
2004-11-12 |
2007-06-14 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
|
US8367805B2
(en)
|
2004-11-12 |
2013-02-05 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
|
US7183969B2
(en)
|
2004-12-22 |
2007-02-27 |
Raytheon Company |
System and technique for calibrating radar arrays
|
|
EP3085389A1
(en)
|
2005-04-07 |
2016-10-26 |
The Trustees Of The University Of Pennsylvania |
Method of increasing the function of an aav vector
|
|
WO2006132118A1
(ja)
|
2005-06-09 |
2006-12-14 |
Matsushita Electric Industrial Co., Ltd. |
振幅誤差補償装置及び直交度誤差補償装置
|
|
US7846724B2
(en)
|
2006-04-11 |
2010-12-07 |
Hoffmann-La Roche Inc. |
Method for selecting CHO cell for production of glycosylated antibodies
|
|
EP3246045B1
(en)
*
|
2007-07-26 |
2025-09-03 |
Osaka University |
Therapeutic agents for ocular inflammatory disease comprising interleukin 6 receptor inhibitor as active ingredient
|
|
ES2644880T3
(es)
|
2008-02-19 |
2017-11-30 |
Uniqure Ip B.V. |
Optimización de expresión de proteínas Rep y Cap parvovirales en las células de insecto
|
|
ES2724122T3
(es)
|
2009-04-30 |
2019-09-06 |
Univ Pennsylvania |
Composiciones para dirigir células de las vías respiratorias de conducción que comprenden construcciones de virus adenoasociado
|
|
WO2010138263A2
(en)
|
2009-05-28 |
2010-12-02 |
University Of Massachusetts |
Novel aav 's and uses thereof
|
|
US10053513B2
(en)
|
2009-11-30 |
2018-08-21 |
Janssen Biotech, Inc. |
Antibody Fc mutants with ablated effector functions
|
|
US8628966B2
(en)
|
2010-04-30 |
2014-01-14 |
City Of Hope |
CD34-derived recombinant adeno-associated vectors for stem cell transduction and systemic therapeutic gene transfer
|
|
US8927514B2
(en)
|
2010-04-30 |
2015-01-06 |
City Of Hope |
Recombinant adeno-associated vectors for targeted treatment
|
|
CN107828820B
(zh)
|
2010-10-27 |
2022-06-07 |
学校法人自治医科大学 |
用于向神经系统细胞导入基因的腺相关病毒粒子
|
|
US9409953B2
(en)
|
2011-02-10 |
2016-08-09 |
The University Of North Carolina At Chapel Hill |
Viral vectors with modified transduction profiles and methods of making and using the same
|
|
CN107012171B
(zh)
|
2011-04-22 |
2021-07-13 |
加利福尼亚大学董事会 |
具有变异衣壳的腺相关病毒病毒体及其使用方法
|
|
EP3147295B2
(en)
|
2011-08-24 |
2023-11-22 |
The Board of Trustees of the Leland Stanford Junior University |
New avv capsid proteins for nucleic acid transfer
|
|
US9382319B2
(en)
|
2011-09-26 |
2016-07-05 |
Jn Biosciences Llc |
Hybrid constant regions
|
|
EP3470523A1
(en)
|
2012-05-09 |
2019-04-17 |
Oregon Health & Science University |
Adeno associated virus plasmids and vectors
|
|
TWI682941B
(zh)
|
2013-02-01 |
2020-01-21 |
美商再生元醫藥公司 |
含嵌合恆定區之抗體
|
|
CA2905952A1
(en)
|
2013-03-13 |
2014-10-02 |
The Children's Hospital Of Philadelphia |
Adeno-associated virus vectors and methods of use thereof
|
|
EA201990558A3
(ru)
|
2013-04-20 |
2021-02-26 |
Рисёрч Инститъют Эт Нэйшнвайд Чилдрен'С Хоспитал |
Доставка нацеленных на экзон 2 полинуклеотидных конструкций u7snrna при помощи рекомбинантного аденоассоциированного вируса
|
|
PT3024498T
(pt)
|
2013-07-22 |
2020-03-06 |
Childrens Hospital Philadelphia |
Variante aav e composições, métodos e usos para transferência genética em células, órgãos e tecidos
|
|
EP3564379A1
(en)
|
2013-09-13 |
2019-11-06 |
California Institute of Technology |
Selective recovery
|
|
NZ718926A
(en)
|
2013-10-11 |
2021-12-24 |
Massachusetts Eye & Ear Infirmary |
Methods of predicting ancestral virus sequences and uses thereof
|
|
US10746742B2
(en)
|
2014-04-25 |
2020-08-18 |
Oregon Health & Science University |
Methods of viral neutralizing antibody epitope mapping
|
|
US10577627B2
(en)
|
2014-06-09 |
2020-03-03 |
Voyager Therapeutics, Inc. |
Chimeric capsids
|
|
AU2015320694B2
(en)
|
2014-09-24 |
2021-11-11 |
City Of Hope |
Adeno-associated virus vector variants for high efficiency genome editing and methods thereof
|
|
WO2016161010A2
(en)
|
2015-03-30 |
2016-10-06 |
Regeneron Pharmaceuticals, Inc. |
Heavy chain constant regions with reduced binding to fc gamma receptors
|
|
GB201508026D0
(en)
|
2015-05-11 |
2015-06-24 |
Ucl Business Plc |
Capsid
|
|
JP6665466B2
(ja)
|
2015-09-26 |
2020-03-13 |
日亜化学工業株式会社 |
半導体発光素子及びその製造方法
|
|
WO2017070491A1
(en)
|
2015-10-23 |
2017-04-27 |
Applied Genetic Technologies Corporation |
Ophthalmic formulations
|
|
SG11201803654TA
(en)
*
|
2015-11-03 |
2018-05-30 |
Sanofi Biotechnology |
Compositions comprising il6r antibodies for the treatment of uveitis and macular edema and methods of using same
|
|
SG11201808440YA
(en)
*
|
2016-04-15 |
2018-10-30 |
Regenxbio Inc |
Treatment of ocular diseases with fully-human post-translationally modified anti-vegf fab
|
|
WO2017180936A1
(en)
*
|
2016-04-15 |
2017-10-19 |
The Trustees Of The University Of Pennsylvania |
Compositions for treatment of wet age-related macular degeneration
|
|
JP2018048133A
(ja)
*
|
2016-09-20 |
2018-03-29 |
参天製薬株式会社 |
炎症性眼疾患の治療及び／又は予防剤
|
|
CN110650733A
(zh)
*
|
2017-02-28 |
2020-01-03 |
阿德夫拉姆生物技术股份有限公司 |
经过修饰的aav衣壳和其用途
|
|
AU2018350992A1
(en)
*
|
2017-10-18 |
2020-05-21 |
Regenxbio Inc. |
Fully-human post-translationally modified antibody therapeutics
|