JP2023546298A5 - - Google Patents

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Publication number
JP2023546298A5
JP2023546298A5 JP2023548543A JP2023548543A JP2023546298A5 JP 2023546298 A5 JP2023546298 A5 JP 2023546298A5 JP 2023548543 A JP2023548543 A JP 2023548543A JP 2023548543 A JP2023548543 A JP 2023548543A JP 2023546298 A5 JP2023546298 A5 JP 2023546298A5
Authority
JP
Japan
Prior art keywords
polypeptide
item
fusion
seq
tgfβ superfamily
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023548543A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023546298A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/055646 external-priority patent/WO2022086988A1/en
Publication of JP2023546298A publication Critical patent/JP2023546298A/ja
Publication of JP2023546298A5 publication Critical patent/JP2023546298A5/ja
Pending legal-status Critical Current

Links

JP2023548543A 2020-10-20 2021-10-19 多機能性及び多価インターロイキン-tgf-ベータ受容体融合ポリペプチド Pending JP2023546298A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063094277P 2020-10-20 2020-10-20
US63/094,277 2020-10-20
PCT/US2021/055646 WO2022086988A1 (en) 2020-10-20 2021-10-19 Multi-functional and multi-valent interleukin-tgf-beta receptor fusion polypeptides

Publications (2)

Publication Number Publication Date
JP2023546298A JP2023546298A (ja) 2023-11-01
JP2023546298A5 true JP2023546298A5 (https=) 2024-10-28

Family

ID=81257992

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023548543A Pending JP2023546298A (ja) 2020-10-20 2021-10-19 多機能性及び多価インターロイキン-tgf-ベータ受容体融合ポリペプチド

Country Status (8)

Country Link
US (2) US11407814B2 (https=)
EP (1) EP4232466A4 (https=)
JP (1) JP2023546298A (https=)
KR (1) KR20230117341A (https=)
CN (1) CN116615441A (https=)
AU (1) AU2021367306A1 (https=)
CA (1) CA3198822A1 (https=)
IL (1) IL302269A (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230117341A (ko) 2020-10-20 2023-08-08 큐라 테라퓨틱스, 인크. 다기능성 및 다가 인터류킨-tgf-베타 수용체 융합 폴리펩티드
CN117120075A (zh) 2021-02-17 2023-11-24 库拉治疗股份有限公司 抗病原体白细胞介素-TGF-β受体融合多肽

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2449753T3 (es) 2007-03-19 2014-03-21 National Research Council Of Canada Proteínas de fusión que comprenden dos dominios de unión tgf-beta
WO2009152610A1 (en) 2008-06-20 2009-12-23 The Royal Institution For The Advancement Of Learning/Mcgill University Interleukin-2/soluble tgf-beta type ii receptor b conjugates and methods and uses thereof
EP3307783B1 (en) * 2015-06-10 2021-01-06 Emory University Compositions and conjugates comprising an interleukin and polypeptides that specifically bind tgf-beta
US20200231652A1 (en) * 2015-08-31 2020-07-23 National Research Council Of Canada Tgf-b-receptor ectodomain fusion molecules and uses thereof
US11168138B2 (en) * 2018-03-26 2021-11-09 Altor Bioscience, Llc Anti-PDL1, IL-15 and TGF-beta receptor combination molecules
CN120365435A (zh) 2018-08-30 2025-07-25 免疫生物公司 单链嵌合多肽和多链嵌合多肽以及其用途
US20210061871A1 (en) 2019-08-29 2021-03-04 Nantbio, Inc. Modified N-810 and Methods Therefor
KR102402276B1 (ko) 2019-11-15 2022-05-26 주식회사 제넥신 변형된 인터루킨-7 및 tgf 베타 수용체 ii를 포함하는 융합단백질 및 이의 용도
TW202233661A (zh) 2020-10-20 2022-09-01 美商克拉治療股份有限公司 多功能及多價介白素-TGF-β受體融合多肽
KR20230117341A (ko) 2020-10-20 2023-08-08 큐라 테라퓨틱스, 인크. 다기능성 및 다가 인터류킨-tgf-베타 수용체 융합 폴리펩티드
CN117120075A (zh) * 2021-02-17 2023-11-24 库拉治疗股份有限公司 抗病原体白细胞介素-TGF-β受体融合多肽

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