JP2023544446A - Ｓｉｋ阻害剤およびその使用方法 - Google Patents

Ｓｉｋ阻害剤およびその使用方法 Download PDF

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Publication number
JP2023544446A
JP2023544446A JP2023542830A JP2023542830A JP2023544446A JP 2023544446 A JP2023544446 A JP 2023544446A JP 2023542830 A JP2023542830 A JP 2023542830A JP 2023542830 A JP2023542830 A JP 2023542830A JP 2023544446 A JP2023544446 A JP 2023544446A
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Japan
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substituted
unsubstituted
subject
compound
monocyclic
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JP2023542830A
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Japanese (ja)
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JP2023544446A5 (https=
Inventor
ブラハム シュルート，
ヴァレット， ベアトリス ル
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Soltego Inc
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Soltego Inc
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Publication of JP2023544446A publication Critical patent/JP2023544446A/ja
Publication of JP2023544446A5 publication Critical patent/JP2023544446A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP2023542830A 2020-09-21 2021-09-21 Ｓｉｋ阻害剤およびその使用方法 Pending JP2023544446A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063081089P 2020-09-21 2020-09-21
US63/081,089 2020-09-21
PCT/US2021/051375 WO2022061312A1 (en) 2020-09-21 2021-09-21 Sik inhibitors and methods of use thereof

Publications (2)

Publication Number Publication Date
JP2023544446A true JP2023544446A (ja) 2023-10-23
JP2023544446A5 JP2023544446A5 (https=) 2024-10-01

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ID=80775691

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JP2023542830A Pending JP2023544446A (ja) 2020-09-21 2021-09-21 Ｓｉｋ阻害剤およびその使用方法

Country Status (7)

Country Link
US (1) US20230265099A1 (https=)
EP (1) EP4213851A4 (https=)
JP (1) JP2023544446A (https=)
CN (1) CN117136061A (https=)
AU (1) AU2021343539A1 (https=)
CA (1) CA3193194A1 (https=)
WO (1) WO2022061312A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4526307A1 (en) * 2022-05-17 2025-03-26 Soltego, Inc. Pyrimidopyrimidone compounds and methods of use thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104418860A (zh) * 2013-08-20 2015-03-18 中国科学院广州生物医药与健康研究院 嘧啶并杂环类化合物及其药用组合物和应用
WO2018053373A1 (en) * 2016-09-16 2018-03-22 The General Hospital Corporation Uses of satl-inducible kinase (sik) inhibitors for treating osteoporosis
WO2018160774A1 (en) * 2017-02-28 2018-09-07 The General Hospital Corporation Uses of pyrimidopyrimidinones as sik inhibitors
JP2019527682A (ja) * 2016-07-05 2019-10-03 ザ ブロード インスティテュート, インコーポレーテッドThe Broad Institute, Inc. 二環式尿素キナーゼインヒビターおよびそれらの使用
WO2020140055A1 (en) * 2018-12-28 2020-07-02 Spv Therapeutics Inc. Cyclin-dependent kinase inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2021262482A1 (en) * 2020-04-28 2023-01-05 Iomx Therapeutics Ag Bicyclic kinase inhibitors and uses thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104418860A (zh) * 2013-08-20 2015-03-18 中国科学院广州生物医药与健康研究院 嘧啶并杂环类化合物及其药用组合物和应用
JP2019527682A (ja) * 2016-07-05 2019-10-03 ザ ブロード インスティテュート, インコーポレーテッドThe Broad Institute, Inc. 二環式尿素キナーゼインヒビターおよびそれらの使用
WO2018053373A1 (en) * 2016-09-16 2018-03-22 The General Hospital Corporation Uses of satl-inducible kinase (sik) inhibitors for treating osteoporosis
WO2018160774A1 (en) * 2017-02-28 2018-09-07 The General Hospital Corporation Uses of pyrimidopyrimidinones as sik inhibitors
WO2020140055A1 (en) * 2018-12-28 2020-07-02 Spv Therapeutics Inc. Cyclin-dependent kinase inhibitors

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
ACS CHEM. BIOL., vol. 11, JPN6025045920, 2016, pages 2105 - 2111, ISSN: 0005726662 *
CHINESE CHEMICAL LETT., vol. 31, JPN6025045919, 2019, pages 1281 - 1287, ISSN: 0005726661 *
J. MED. CHEM., vol. 56, JPN6025045918, 2013, pages 8803 - 8813, ISSN: 0005726660 *
J. MED. CHEM., vol. 61, JPN6025045917, 2018, pages 2353 - 2371, ISSN: 0005726659 *

Also Published As

Publication number Publication date
WO2022061312A1 (en) 2022-03-24
EP4213851A4 (en) 2025-08-06
CN117136061A (zh) 2023-11-28
AU2021343539A9 (en) 2024-09-26
AU2021343539A1 (en) 2023-05-18
US20230265099A1 (en) 2023-08-24
EP4213851A1 (en) 2023-07-26
CA3193194A1 (en) 2022-03-24

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