CN117136061A - Sik抑制剂及其使用方法 - Google Patents

Sik抑制剂及其使用方法 Download PDF

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Publication number
CN117136061A
CN117136061A CN202180078421.4A CN202180078421A CN117136061A CN 117136061 A CN117136061 A CN 117136061A CN 202180078421 A CN202180078421 A CN 202180078421A CN 117136061 A CN117136061 A CN 117136061A
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CN
China
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substituted
compound
unsubstituted
subject
polycyclic
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Pending
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CN202180078421.4A
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English (en)
Chinese (zh)
Inventor
B·斯鲁特
B·勒瓦莱
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Soltego Corp
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Soltego Corp
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Publication of CN117136061A publication Critical patent/CN117136061A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CN202180078421.4A 2020-09-21 2021-09-21 Sik抑制剂及其使用方法 Pending CN117136061A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063081089P 2020-09-21 2020-09-21
US63/081,089 2020-09-21
PCT/US2021/051375 WO2022061312A1 (en) 2020-09-21 2021-09-21 Sik inhibitors and methods of use thereof

Publications (1)

Publication Number Publication Date
CN117136061A true CN117136061A (zh) 2023-11-28

Family

ID=80775691

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202180078421.4A Pending CN117136061A (zh) 2020-09-21 2021-09-21 Sik抑制剂及其使用方法

Country Status (7)

Country Link
US (1) US20230265099A1 (https=)
EP (1) EP4213851A4 (https=)
JP (1) JP2023544446A (https=)
CN (1) CN117136061A (https=)
AU (1) AU2021343539A1 (https=)
CA (1) CA3193194A1 (https=)
WO (1) WO2022061312A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4526307A1 (en) * 2022-05-17 2025-03-26 Soltego, Inc. Pyrimidopyrimidone compounds and methods of use thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110225914A (zh) * 2016-07-05 2019-09-10 布罗德研究所股份有限公司 双环脲激酶抑制剂及其用途
CN111163771A (zh) * 2017-02-28 2020-05-15 通用医疗公司 嘧啶并嘧啶酮类作为sik抑制剂的用途
US20200179387A1 (en) * 2016-09-16 2020-06-11 The General Hospital Corporation Uses of salt-inducible kinase (sik) inhibitors for treating osteoporosis
WO2020140055A1 (en) * 2018-12-28 2020-07-02 Spv Therapeutics Inc. Cyclin-dependent kinase inhibitors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104418860B (zh) * 2013-08-20 2016-09-07 中国科学院广州生物医药与健康研究院 嘧啶并杂环类化合物及其药用组合物和应用
AU2021262482A1 (en) * 2020-04-28 2023-01-05 Iomx Therapeutics Ag Bicyclic kinase inhibitors and uses thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110225914A (zh) * 2016-07-05 2019-09-10 布罗德研究所股份有限公司 双环脲激酶抑制剂及其用途
US20200179387A1 (en) * 2016-09-16 2020-06-11 The General Hospital Corporation Uses of salt-inducible kinase (sik) inhibitors for treating osteoporosis
CN111163771A (zh) * 2017-02-28 2020-05-15 通用医疗公司 嘧啶并嘧啶酮类作为sik抑制剂的用途
WO2020140055A1 (en) * 2018-12-28 2020-07-02 Spv Therapeutics Inc. Cyclin-dependent kinase inhibitors

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NISMA MUJAHID等: "A UV-Independent Topical Small-Molecule Approach for Melanin Production in Human Skin", 《CELL REPORTS》, vol. 19, 13 June 2017 (2017-06-13), pages 2177 - 2184, XP055381347, DOI: 10.1016/j.celrep.2017.05.042 *

Also Published As

Publication number Publication date
WO2022061312A1 (en) 2022-03-24
EP4213851A4 (en) 2025-08-06
AU2021343539A9 (en) 2024-09-26
AU2021343539A1 (en) 2023-05-18
US20230265099A1 (en) 2023-08-24
EP4213851A1 (en) 2023-07-26
JP2023544446A (ja) 2023-10-23
CA3193194A1 (en) 2022-03-24

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