JP2023544162A5 - - Google Patents

Info

Publication number
JP2023544162A5
JP2023544162A5 JP2023520049A JP2023520049A JP2023544162A5 JP 2023544162 A5 JP2023544162 A5 JP 2023544162A5 JP 2023520049 A JP2023520049 A JP 2023520049A JP 2023520049 A JP2023520049 A JP 2023520049A JP 2023544162 A5 JP2023544162 A5 JP 2023544162A5
Authority
JP
Japan
Prior art keywords
modified
modified oligonucleotide
nucleic acid
nucleoside
nucleosides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023520049A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023544162A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/053107 external-priority patent/WO2022072787A1/en
Publication of JP2023544162A publication Critical patent/JP2023544162A/ja
Publication of JP2023544162A5 publication Critical patent/JP2023544162A5/ja
Pending legal-status Critical Current

Links

JP2023520049A 2020-10-01 2021-10-01 Ｃｈｍｐ７を調節するための化合物 Pending JP2023544162A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202063086576P 2020-10-01 2020-10-01
US63/086,576 2020-10-01
US202063119448P 2020-11-30 2020-11-30
US63/119,448 2020-11-30
US202163139715P 2021-01-20 2021-01-20
US63/139,715 2021-01-20
PCT/US2021/053107 WO2022072787A1 (en) 2020-10-01 2021-10-01 Compounds for modulating chmp7

Publications (2)

Publication Number Publication Date
JP2023544162A JP2023544162A (ja) 2023-10-20
JP2023544162A5 true JP2023544162A5 (cg-RX-API-DMAC10.html) 2024-10-07

Family

ID=80950932

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023520049A Pending JP2023544162A (ja) 2020-10-01 2021-10-01 Ｃｈｍｐ７を調節するための化合物

Country Status (4)

Country Link
US (1) US20240002852A1 (cg-RX-API-DMAC10.html)
EP (1) EP4222261A4 (cg-RX-API-DMAC10.html)
JP (1) JP2023544162A (cg-RX-API-DMAC10.html)
WO (1) WO2022072787A1 (cg-RX-API-DMAC10.html)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023549160A (ja) * 2020-11-10 2023-11-22 ザ・ジョンズ・ホプキンス・ユニバーシティ 神経変性疾患の治療のために神経細胞におけるｃｈｍｐ７発現を阻害するための方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2563921B1 (en) * 2010-04-30 2016-11-23 Cellectis Method for modulating double-strand break-induced homologous recombination
WO2012122015A2 (en) * 2011-03-04 2012-09-13 Immune Disease Institute, Inc. Selective inhibitors of tumor-initiating cells
IL300258A (en) * 2020-08-07 2023-03-01 Ionis Pharmaceuticals Inc Compounds and methods for modulating SCN2A

Similar Documents

Publication Publication Date Title
CN113164509B (zh) 用于抑制17β-HSD 13型(HSD17B13)表达的RNAi试剂、其组合物和使用方法
JP4118348B2 (ja) Ｇキャプ安定化したオリゴヌクレオチド
ES2238044T3 (es) Modulacion de la estimulacion inmunologica mediada por el oligonucleotido cpg mediante modificacion posicional de nucleosidos.
JP2022515193A5 (cg-RX-API-DMAC10.html)
JP2026020334A (ja) エンドソーム切断可能なリンカー
JP2025000693A (ja) Ａｐｐの発現を低減するための化合物及び方法
JP2019525918A5 (cg-RX-API-DMAC10.html)
JP2019513771A (ja) トリチル−モノ−ＧａｌＮＡｃ化合物とその利用
CN110832077B (zh) 用于抑制α-ENaC表达的RNAi剂及使用方法
JP2022518929A5 (cg-RX-API-DMAC10.html)
JP2023543215A5 (cg-RX-API-DMAC10.html)
JP2022527105A5 (cg-RX-API-DMAC10.html)
JP2024109582A (ja) トリループを含む二本鎖核酸インヒビター分子
CN105008533A (zh) 嵌合单链反义多核苷酸和双链反义试剂
JP2021072862A (ja) Ｂ型肝炎感染の治療用のＰＡＰＤ５及びＰＡＰＤ７ ｍＲＮＡを低減させるための核酸分子
JP7446443B2 (ja) Ｓｍｎ２を調節するための化合物及び方法
JP2022520986A5 (cg-RX-API-DMAC10.html)
TW202321449A (zh) 用於寡核苷酸劑的基於寡核苷酸的遞送載體及其使用方法
JP2023018065A (ja) Ｒｅｖｅｒｓｉｒ（商標）化合物
JP2019534009A5 (cg-RX-API-DMAC10.html)
JP2021510511A5 (cg-RX-API-DMAC10.html)
JP2023536472A5 (cg-RX-API-DMAC10.html)
KR20200144100A (ko) Tm-증가 뉴클레오타이드로 변형된 이중-가닥 핵산 억제제 분자
CA3136676A1 (en) Double-stranded nucleic acid inhibitor molecules with shortened sense strands
JP2023528755A5 (cg-RX-API-DMAC10.html)