|
US4683195A
(en)
|
1986-01-30 |
1987-07-28 |
Cetus Corporation |
Process for amplifying, detecting, and/or-cloning nucleic acid sequences
|
|
FR2640638B1
(fr)
|
1988-12-20 |
1991-02-15 |
Commissariat Energie Atomique |
Bioreacteur et dispositif pour la culture de cellules animales
|
|
US5194376A
(en)
|
1989-02-28 |
1993-03-16 |
University Of Ottawa |
Baculovirus expression system capable of producing foreign gene proteins at high levels
|
|
US5478745A
(en)
|
1992-12-04 |
1995-12-26 |
University Of Pittsburgh |
Recombinant viral vector system
|
|
WO1995013365A1
(en)
|
1993-11-09 |
1995-05-18 |
Targeted Genetics Corporation |
Generation of high titers of recombinant aav vectors
|
|
US6204059B1
(en)
|
1994-06-30 |
2001-03-20 |
University Of Pittsburgh |
AAV capsid vehicles for molecular transfer
|
|
US5872005A
(en)
|
1994-11-03 |
1999-02-16 |
Cell Genesys Inc. |
Packaging cell lines for adeno-associated viral vectors
|
|
US6281010B1
(en)
|
1995-06-05 |
2001-08-28 |
The Trustees Of The University Of Pennsylvania |
Adenovirus gene therapy vehicle and cell line
|
|
US5756283A
(en)
|
1995-06-05 |
1998-05-26 |
The Trustees Of The University Of Pennsylvania |
Method for improved production of recombinant adeno-associated viruses for gene therapy
|
|
US5622856A
(en)
|
1995-08-03 |
1997-04-22 |
Avigen |
High efficiency helper system for AAV vector production
|
|
US6632670B1
(en)
|
1995-09-08 |
2003-10-14 |
Genzyme Corporation |
AAV vectors for gene therapy
|
|
DE19608753C1
(de)
|
1996-03-06 |
1997-06-26 |
Medigene Gmbh |
Transduktionssystem und seine Verwendung
|
|
WO1998009524A1
(en)
|
1996-09-06 |
1998-03-12 |
Chiron Corporation |
Methods and compositions for liver specific delivery of therapeutic molecules using recombinant aav vectors
|
|
EP0931158A1
(en)
|
1996-09-06 |
1999-07-28 |
The Trustees Of The University Of Pennsylvania |
An inducible method for production of recombinant adeno-associated viruses utilizing t7 polymerase
|
|
WO1998022588A2
(en)
|
1996-11-20 |
1998-05-28 |
Introgen Therapeutics, Inc. |
An improved method for the production and purification of adenoviral vectors
|
|
US7732129B1
(en)
|
1998-12-01 |
2010-06-08 |
Crucell Holland B.V. |
Method for the production and purification of adenoviral vectors
|
|
FR2756297B1
(fr)
|
1996-11-22 |
1999-01-08 |
Centre Nat Rech Scient |
Procede de production de virus recombinants
|
|
US6207455B1
(en)
|
1997-05-01 |
2001-03-27 |
Lung-Ji Chang |
Lentiviral vectors
|
|
US6156303A
(en)
|
1997-06-11 |
2000-12-05 |
University Of Washington |
Adeno-associated virus (AAV) isolates and AAV vectors derived therefrom
|
|
US6989264B2
(en)
|
1997-09-05 |
2006-01-24 |
Targeted Genetics Corporation |
Methods for generating high titer helper-free preparations of released recombinant AAV vectors
|
|
US6566118B1
(en)
|
1997-09-05 |
2003-05-20 |
Targeted Genetics Corporation |
Methods for generating high titer helper-free preparations of released recombinant AAV vectors
|
|
WO1999014354A1
(en)
|
1997-09-19 |
1999-03-25 |
The Trustees Of The University Of The Pennsylvania |
Methods and vector constructs useful for production of recombinant aav
|
|
EP1015619A1
(en)
|
1997-09-19 |
2000-07-05 |
The Trustees Of The University Of Pennsylvania |
Methods and cell line useful for production of recombinant adeno-associated viruses
|
|
CA2304983A1
(en)
|
1997-09-24 |
1999-04-01 |
The Regents Of The University Of California |
Non-primate lentiviral vectors and packaging systems
|
|
US5994136A
(en)
|
1997-12-12 |
1999-11-30 |
Cell Genesys, Inc. |
Method and means for producing high titer, safe, recombinant lentivirus vectors
|
|
EP0924298A1
(en)
|
1997-12-18 |
1999-06-23 |
Stichting Instituut voor Dierhouderij en Diergezondheid (ID-DLO) |
Protein expression in baculovirus vector expression systems
|
|
CN1292033A
(zh)
|
1998-03-04 |
2001-04-18 |
昂尼克斯药物公司 |
用于遗传物质高通量表达的杆状病毒表达系统和方法
|
|
EP1064393B1
(en)
|
1998-03-20 |
2004-12-29 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for helper-free production of recombinant adeno-associated viruses
|
|
US6953690B1
(en)
|
1998-03-20 |
2005-10-11 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for helper-free production of recombinant adeno-associated viruses
|
|
US20030017138A1
(en)
|
1998-07-08 |
2003-01-23 |
Menzo Havenga |
Chimeric adenoviruses
|
|
AU780231B2
(en)
|
1998-11-10 |
2005-03-10 |
University Of North Carolina At Chapel Hill, The |
Virus vectors and methods of making and administering the same
|
|
US7262049B2
(en)
|
1999-03-16 |
2007-08-28 |
Dana-Farber Cancer Institute, Inc. |
Pseudotyped lentiviral vectors and uses thereof
|
|
US6258595B1
(en)
|
1999-03-18 |
2001-07-10 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for helper-free production of recombinant adeno-associated viruses
|
|
JP4693244B2
(ja)
|
1999-03-18 |
2011-06-01 |
ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
組換えアデノ随伴ウイルスのヘルパー無しの生産のための組成物および方法
|
|
ES2372823T3
(es)
|
1999-05-17 |
2012-01-26 |
Crucell Holland B.V. |
Adenovirus recombinante del serotipo ad11.
|
|
WO2003104467A1
(en)
|
2002-04-25 |
2003-12-18 |
Crucell Holland B.V. |
Means and methods for the production of adenovirus vectors
|
|
CA2375098A1
(en)
|
1999-06-02 |
2000-12-14 |
Trustees Of The University Of Pennsylvania |
Compositions and methods useful for production of recombinant viruses which require helper viruses
|
|
JP2003523320A
(ja)
|
1999-09-29 |
2003-08-05 |
ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
ウイルスベクターの迅速なpeg改変方法、高められた遺伝子形質導入のための組成物、高められた物理的安定性を伴う組成物、およびそのための用途
|
|
US6365394B1
(en)
|
1999-09-29 |
2002-04-02 |
The Trustees Of The University Of Pennsylvania |
Cell lines and constructs useful in production of E1-deleted adenoviruses in absence of replication competent adenovirus
|
|
DE69941703D1
(de)
|
1999-10-11 |
2010-01-07 |
Pasteur Institut |
Lentivirale Vektoren für die Herstellung von immunotherapeutischen Zusammensetzungen
|
|
GB0024550D0
(https=)
|
2000-10-06 |
2000-11-22 |
Oxford Biomedica Ltd |
|
|
US7749492B2
(en)
|
2001-01-05 |
2010-07-06 |
Nationwide Children's Hospital, Inc. |
AAV vectors and methods
|
|
RU2305708C2
(ru)
|
2001-10-02 |
2007-09-10 |
Энститю Клейтон Де Ля Решерш |
Рекомбинантный лентивирусный вектор, клетка-хозяин, трансдуцированная лентивирусным вектором, способ ее трансдукции и применение
|
|
US7261544B2
(en)
|
2003-05-21 |
2007-08-28 |
Genzyme Corporation |
Methods for producing preparations of recombinant AAV virions substantially free of empty capsids
|
|
EP1486567A1
(en)
|
2003-06-11 |
2004-12-15 |
Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts |
Improved adeno-associated virus (AAV) vector for gene therapy
|
|
SI1633772T1
(sl)
|
2003-06-19 |
2016-06-30 |
Genzyme Corporation |
AAV virioni z zmanjšano imunoreaktivnostjo in uporaba za ta namen
|
|
CA2528511C
(en)
|
2003-06-20 |
2015-11-03 |
The Trustees Of The University Of Pennsylvania |
Methods of generating chimeric adenoviruses and uses for such chimeric adenoviruses
|
|
US7291498B2
(en)
|
2003-06-20 |
2007-11-06 |
The Trustees Of The University Of Pennsylvania |
Methods of generating chimeric adenoviruses and uses for such chimeric adenoviruses
|
|
US9441244B2
(en)
|
2003-06-30 |
2016-09-13 |
The Regents Of The University Of California |
Mutant adeno-associated virus virions and methods of use thereof
|
|
US8106180B2
(en)
|
2003-08-07 |
2012-01-31 |
Whitehead Institute For Biomedical Research |
Methods and products for expression of micro RNAs
|
|
US20050142581A1
(en)
|
2003-09-04 |
2005-06-30 |
Griffey Richard H. |
Microrna as ligands and target molecules
|
|
WO2005056761A2
(en)
|
2003-12-05 |
2005-06-23 |
Massachusetts Institute Of Technology |
REAGENTS AND METHODS FOR IDENTIFICATION OF RNAi PATHWAY GENES AND CHEMICAL MODULATORS OF RNAi
|
|
US20060166363A1
(en)
|
2004-01-27 |
2006-07-27 |
Sergei Zolotukhin |
Modified baculovirus expression system for production of pseudotyped rAAV vector
|
|
KR100614827B1
(ko)
|
2004-05-06 |
2006-08-25 |
재단법인서울대학교산학협력재단 |
양방향 은닉 마코프 모델을 이용한 완숙한마이크로알엔에이 위치예측방법 및 이를 구현하기 위한컴퓨터 프로그램을 기록한 저장매체
|
|
US7427396B2
(en)
|
2004-06-03 |
2008-09-23 |
Genzyme Corporation |
AAV vectors for gene delivery to the lung
|
|
US7632509B2
(en)
|
2005-07-19 |
2009-12-15 |
Biosante Pharmaceuticals, Inc. |
Methods to express recombinant proteins from lentiviral vectors
|
|
US8895715B2
(en)
*
|
2008-05-09 |
2014-11-25 |
The University Of British Columbia |
S100B mini-promoters
|
|
US10041049B2
(en)
|
2008-11-03 |
2018-08-07 |
Janssen Vaccines & Prevention B.V. |
Method for the production of adenoviral vectors
|
|
WO2013004716A1
(en)
*
|
2011-07-04 |
2013-01-10 |
Universität Basel |
Peptide beads
|
|
CA2853482C
(en)
|
2011-10-28 |
2020-05-19 |
Joshua Grieger |
Cell line for production of adeno-associated virus
|
|
ES2926774T3
(es)
|
2013-03-15 |
2022-10-28 |
Univ North Carolina Chapel Hill |
Métodos y composiciones para vectores AAV de doble unión de glicano
|
|
EP3151866B1
(en)
|
2014-06-09 |
2023-03-08 |
Voyager Therapeutics, Inc. |
Chimeric capsids
|
|
EP3808849A1
(en)
|
2017-08-03 |
2021-04-21 |
Voyager Therapeutics, Inc. |
Compositions and methods for delivery of aav
|
|
EP3752179A4
(en)
*
|
2018-02-15 |
2021-10-06 |
Duke University |
GENE EDITING USING A UNIVERSAL GENOMIC ENGINEERING TECHNOLOGY INDEPENDENT OF HOMOLOGY
|
|
CA3096407A1
(en)
|
2018-04-09 |
2019-10-17 |
Allen Institute |
Rescuing voltage-gated sodium channel function in inhibitory neurons
|
|
WO2020076614A1
(en)
|
2018-10-08 |
2020-04-16 |
Allen Institute |
Artificial expression constructs for selectively modulating gene expression in interneurons
|
|
WO2020097121A1
(en)
|
2018-11-05 |
2020-05-14 |
Allen Institute |
Artificial expression constructs for selectively modulating gene expression in excitatory cortical neurons
|