JP2023540464A5 - - Google Patents
Info
- Publication number
- JP2023540464A5 JP2023540464A5 JP2023512663A JP2023512663A JP2023540464A5 JP 2023540464 A5 JP2023540464 A5 JP 2023540464A5 JP 2023512663 A JP2023512663 A JP 2023512663A JP 2023512663 A JP2023512663 A JP 2023512663A JP 2023540464 A5 JP2023540464 A5 JP 2023540464A5
- Authority
- JP
- Japan
- Prior art keywords
- promoter
- sequence
- acid sequence
- poly
- codon
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010706505.5A CN113952473A (zh) | 2020-07-21 | 2020-07-21 | 用于治疗眼部疾病的组合物和方法 |
| CN202010706658.XA CN113952474A (zh) | 2020-07-21 | 2020-07-21 | 用于治疗眼部疾病的组合物和方法 |
| PCT/IB2021/000498 WO2022018516A1 (en) | 2020-07-21 | 2021-07-20 | Composition and method for treating eye diseases |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023540464A JP2023540464A (ja) | 2023-09-25 |
| JP2023540464A5 true JP2023540464A5 (enExample) | 2024-07-26 |
| JP7842082B2 JP7842082B2 (ja) | 2026-04-07 |
Family
ID=79728536
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023512663A Active JP7842082B2 (ja) | 2020-07-21 | 2021-07-20 | 眼疾患を処置するための組成物および方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20230295243A1 (enExample) |
| EP (1) | EP4185333A4 (enExample) |
| JP (1) | JP7842082B2 (enExample) |
| CN (1) | CN116323949A (enExample) |
| AU (1) | AU2021313839A1 (enExample) |
| CA (1) | CA3186830A1 (enExample) |
| WO (1) | WO2022018516A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112020012336A2 (pt) | 2017-12-19 | 2021-03-30 | Akouos, Inc. | Administração de anticorpos terapêuticos mediada por aav para o ouvido interno |
| IL303317A (en) | 2020-12-01 | 2023-07-01 | Akouos Inc | ANTI-NATURAL ANTIBODY STRUCTURES AND RELATED METHODS FOR THE TREATMENT OF SYMPTOMS ASSOCIATED WITH VESTIBULAR SWANNOMA |
| KR20240145489A (ko) * | 2022-02-02 | 2024-10-07 | 애드베룸 바이오테크놀로지스, 인코포레이티드 | 아플리베르셉트를 코딩하는 aav2 변이체를 사용하여 안구 신생혈관 질환을 치료하는 방법 |
| CN120826472A (zh) * | 2023-03-10 | 2025-10-21 | 阿德夫拉姆生物技术股份有限公司 | 昆虫细胞中重组腺相关病毒（rAAV）的生产 |
| WO2025030169A2 (en) * | 2023-08-03 | 2025-02-06 | Arcum Vision Inc. | Enhanced formulation of polymyxin b/ trimethoprim and rifampin and methods for ophthalmic uses |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE453716T1 (de) * | 2004-08-03 | 2010-01-15 | Geneart Ag | Verfahren zur modulation der genexpression durch änderung des cpg gehalts |
| DE102004037611B4 (de) * | 2004-08-03 | 2013-10-02 | Geneart Ag | Induzierbare Genexpression |
| WO2015109898A1 (zh) * | 2014-01-24 | 2015-07-30 | 上海恒瑞医药有限公司 | VEGF与PDGFRβ双特异性融合蛋白及其用途 |
| CN108347932B (zh) * | 2015-02-20 | 2022-09-13 | 衣阿华大学研究基金会 | 用于治疗遗传性眼病的方法和组合物 |
| SI3471780T1 (sl) * | 2016-06-16 | 2021-03-31 | Adverum Biotechnologies, Inc. | Zdravljenje SDM-ja z uporabo različice AAV2 z afliberceptom |
| AU2018350990A1 (en) * | 2017-10-18 | 2020-05-21 | Regenxbio Inc. | Treatment of ocular diseases and metastatic colon cancer with human post-translationally modified VEGF-Trap |
| ES2946747T3 (es) * | 2017-11-27 | 2023-07-25 | 4D Molecular Therapeutics Inc | Variantes de cápsides de virus adenoasociado y su utilización para inhibir la angiogénesis |
| BR112020012336A2 (pt) * | 2017-12-19 | 2021-03-30 | Akouos, Inc. | Administração de anticorpos terapêuticos mediada por aav para o ouvido interno |
| WO2019195423A1 (en) * | 2018-04-03 | 2019-10-10 | Stridebio, Inc. | Virus vectors for targeting ophthalmic tissues |
| AU2019381776A1 (en) * | 2018-11-16 | 2021-07-01 | AskBio Inc. | Therapeutic adeno-associated virus for treating Pompe disease |
| WO2021050649A1 (en) * | 2019-09-11 | 2021-03-18 | Adverum Biotechnologies, Inc. | Methods of treating ocular neovascular diseases using aav2 variants encoding aflibercept |
| WO2022079453A1 (en) * | 2020-10-16 | 2022-04-21 | Gyroscope Therapeutics Limited | Nucleic acid encoding an anti-vegf entity and a negative complement regulator and uses thereof for the treatment of age-related macular degeneration |
| KR20230167100A (ko) * | 2021-04-09 | 2023-12-07 | 에이버맥스 바이오파마 인크. | 안구 트랜스진 발현을 위한 조성물 및 방법 |
| NZ804423A (en) * | 2021-04-27 | 2026-01-30 | 4D Molecular Therapeutics Inc | Compositions and methods for treatment of ocular disease associated with angiogenesis |
| WO2022247917A1 (zh) * | 2021-05-28 | 2022-12-01 | 上海瑞宏迪医药有限公司 | 衣壳变异的重组腺相关病毒及其应用 |
-
2021
- 2021-07-20 AU AU2021313839A patent/AU2021313839A1/en active Pending
- 2021-07-20 WO PCT/IB2021/000498 patent/WO2022018516A1/en not_active Ceased
- 2021-07-20 EP EP21845723.2A patent/EP4185333A4/en active Pending
- 2021-07-20 CA CA3186830A patent/CA3186830A1/en active Pending
- 2021-07-20 JP JP2023512663A patent/JP7842082B2/ja active Active
- 2021-07-20 CN CN202180064547.6A patent/CN116323949A/zh active Pending
-
2023
- 2023-01-20 US US18/157,599 patent/US20230295243A1/en active Pending
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