JP2023540054A5 - - Google Patents
Info
- Publication number
- JP2023540054A5 JP2023540054A5 JP2023513708A JP2023513708A JP2023540054A5 JP 2023540054 A5 JP2023540054 A5 JP 2023540054A5 JP 2023513708 A JP2023513708 A JP 2023513708A JP 2023513708 A JP2023513708 A JP 2023513708A JP 2023540054 A5 JP2023540054 A5 JP 2023540054A5
- Authority
- JP
- Japan
- Prior art keywords
- approximately
- pharmaceutical composition
- grams
- progranulin
- brain mass
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063070639P | 2020-08-26 | 2020-08-26 | |
| US63/070,639 | 2020-08-26 | ||
| PCT/US2021/047686 WO2022046988A1 (en) | 2020-08-26 | 2021-08-26 | Recombinant adeno-associated virus for treatment of grn-associated adult-onset neurodegeneration |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023540054A JP2023540054A (ja) | 2023-09-21 |
| JP2023540054A5 true JP2023540054A5 (https=) | 2024-08-30 |
Family
ID=78032503
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023513708A Pending JP2023540054A (ja) | 2020-08-26 | 2021-08-26 | Ｇｒｎ関連成人発症性神経変性の治療のための組換えアデノ随伴ウイルス |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20230364264A1 (https=) |
| EP (1) | EP4204014A1 (https=) |
| JP (1) | JP2023540054A (https=) |
| KR (1) | KR20230058102A (https=) |
| CN (1) | CN116887867A (https=) |
| AR (1) | AR123358A1 (https=) |
| AU (1) | AU2021332331A1 (https=) |
| BR (1) | BR112023002904A2 (https=) |
| CA (1) | CA3189107A1 (https=) |
| IL (1) | IL300622A (https=) |
| MX (1) | MX2023002364A (https=) |
| TW (1) | TW202227633A (https=) |
| WO (1) | WO2022046988A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112021015817A2 (pt) | 2019-02-22 | 2021-10-13 | The Trustees Of The University Of Pennsylvania | Vírus adeno-associado recombinante para tratamento de neurodegeneração com início na idade adulta associado a grn |
| US20250295807A1 (en) * | 2021-11-15 | 2025-09-25 | The Trustees Of The University Of Pennsylvania | Compositions for drg-specific reduction of transgene expression |
| WO2024035649A1 (en) * | 2022-08-08 | 2024-02-15 | Shape Therapeutics Inc. | Compositions for progranulin expression and methods of use thereof |
| GB202216168D0 (en) | 2022-10-31 | 2022-12-14 | UCB Biopharma SRL | Route of administration |
| WO2024191873A1 (en) * | 2023-03-10 | 2024-09-19 | Biogen Ma Inc. | Packaging plasmids for aav production |
| TW202548022A (zh) * | 2024-03-03 | 2025-12-16 | 美商帕西奇生物公司 | 用於治療神經退化性病症之重組腺相關病毒 |
| WO2025231406A1 (en) * | 2024-05-02 | 2025-11-06 | The Children's Hospital Of Philadelphia | Methods to increase transduction of ependyma cells in brain |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5139941A (en) | 1985-10-31 | 1992-08-18 | University Of Florida Research Foundation, Inc. | AAV transduction vectors |
| US5436146A (en) | 1989-09-07 | 1995-07-25 | The Trustees Of Princeton University | Helper-free stocks of recombinant adeno-associated virus vectors |
| US6268213B1 (en) | 1992-06-03 | 2001-07-31 | Richard Jude Samulski | Adeno-associated virus vector and cis-acting regulatory and promoter elements capable of expressing at least one gene and method of using same for gene therapy |
| US5869305A (en) | 1992-12-04 | 1999-02-09 | The University Of Pittsburgh | Recombinant viral vector system |
| US6204059B1 (en) | 1994-06-30 | 2001-03-20 | University Of Pittsburgh | AAV capsid vehicles for molecular transfer |
| US6093570A (en) | 1995-06-07 | 2000-07-25 | The University Of North Carolina At Chapel Hill | Helper virus-free AAV production |
| US5741683A (en) | 1995-06-07 | 1998-04-21 | The Research Foundation Of State University Of New York | In vitro packaging of adeno-associated virus DNA |
| US6548286B1 (en) | 1997-04-14 | 2003-04-15 | Cell Genesys, Inc. | Methods for increasing the efficiency of recombinant AAV product |
| US6146874A (en) | 1998-05-27 | 2000-11-14 | University Of Florida | Method of preparing recombinant adeno-associated virus compositions |
| US6759237B1 (en) | 1998-11-05 | 2004-07-06 | The Trustees Of The University Of Pennsylvania | Adeno-associated virus serotype 1 nucleic acid sequences, vectors and host cells containing same |
| AU780231B2 (en) | 1998-11-10 | 2005-03-10 | University Of North Carolina At Chapel Hill, The | Virus vectors and methods of making and administering the same |
| US7201898B2 (en) | 2000-06-01 | 2007-04-10 | The University Of North Carolina At Chapel Hill | Methods and compounds for controlled release of recombinant parvovirus vectors |
| MX359371B (es) | 2001-11-13 | 2018-09-25 | Univ Pennsylvania | Un metodo para detectar y/o identificar secuencias del virus adeno-asociado y aislamiento de secuencias novedosas identificadas de ese modo. |
| AU2003274397A1 (en) | 2002-06-05 | 2003-12-22 | University Of Florida | Production of pseudotyped recombinant aav virions |
| EP2345731B1 (en) | 2003-09-30 | 2015-10-21 | The Trustees of the University of Pennsylvania | Adeno-associated virus (AAV) clades, sequences, vectors containing same, and uses thereof |
| ES2525067T3 (es) | 2005-04-07 | 2014-12-17 | The Trustees Of The University Of Pennsylvania | Método de incremento de la función de un vector de AAV |
| US7588772B2 (en) | 2006-03-30 | 2009-09-15 | Board Of Trustees Of The Leland Stamford Junior University | AAV capsid library and AAV capsid proteins |
| WO2011126808A2 (en) | 2010-03-29 | 2011-10-13 | The Trustees Of The University Of Pennsylvania | Pharmacologically induced transgene ablation system |
| FR2977562B1 (fr) | 2011-07-06 | 2016-12-23 | Gaztransport Et Technigaz | Cuve etanche et thermiquement isolante integree dans une structure porteuse |
| US11028372B2 (en) | 2015-12-11 | 2021-06-08 | The Trustees Of The University Of Pennsylvania | Scalable purification method for AAVRH10 |
| ES2934848T3 (es) | 2015-12-11 | 2023-02-27 | Univ Pennsylvania | Método de purificación escalable para AAV8 |
| WO2017100674A1 (en) | 2015-12-11 | 2017-06-15 | The Trustees Of The University Of Pennsylvania | Scalable purification method for aav1 |
| EP3387138B1 (en) | 2015-12-11 | 2022-01-26 | The Trustees Of The University Of Pennsylvania | Scalable purification method for aav9 |
| CA3012195A1 (en) * | 2016-02-03 | 2017-08-10 | The Trustees Of The University Of Pennsylvania | Gene therapy for treating mucopolysaccharidosis type i |
| US20190328906A1 (en) * | 2016-03-02 | 2019-10-31 | The Children's Hospital Of Philadelphia | Therapy for frontotemporal dementia |
| PT3589730T (pt) | 2017-02-28 | 2024-02-28 | Univ Pennsylvania | Vetor de vírus adenoassociado (aav) de clado f e suas utilizações |
| BR112021015817A2 (pt) * | 2019-02-22 | 2021-10-13 | The Trustees Of The University Of Pennsylvania | Vírus adeno-associado recombinante para tratamento de neurodegeneração com início na idade adulta associado a grn |
-
2021
- 2021-08-26 EP EP21783625.3A patent/EP4204014A1/en active Pending
- 2021-08-26 JP JP2023513708A patent/JP2023540054A/ja active Pending
- 2021-08-26 WO PCT/US2021/047686 patent/WO2022046988A1/en not_active Ceased
- 2021-08-26 TW TW110131628A patent/TW202227633A/zh unknown
- 2021-08-26 CN CN202180072913.2A patent/CN116887867A/zh active Pending
- 2021-08-26 KR KR1020237010072A patent/KR20230058102A/ko active Pending
- 2021-08-26 US US18/040,971 patent/US20230364264A1/en active Pending
- 2021-08-26 CA CA3189107A patent/CA3189107A1/en active Pending
- 2021-08-26 AR ARP210102410A patent/AR123358A1/es unknown
- 2021-08-26 BR BR112023002904A patent/BR112023002904A2/pt unknown
- 2021-08-26 AU AU2021332331A patent/AU2021332331A1/en active Pending
- 2021-08-26 IL IL300622A patent/IL300622A/en unknown
- 2021-08-26 MX MX2023002364A patent/MX2023002364A/es unknown
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