JP2023539047A5 - - Google Patents

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Publication number
JP2023539047A5
JP2023539047A5 JP2023509698A JP2023509698A JP2023539047A5 JP 2023539047 A5 JP2023539047 A5 JP 2023539047A5 JP 2023509698 A JP2023509698 A JP 2023509698A JP 2023509698 A JP2023509698 A JP 2023509698A JP 2023539047 A5 JP2023539047 A5 JP 2023539047A5
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JP
Japan
Prior art keywords
patients
patients weighing
day
composition according
antibody
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2023509698A
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English (en)
Japanese (ja)
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JP7821160B2 (ja
JP2023539047A (ja
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Priority claimed from PCT/US2021/045823 external-priority patent/WO2022036151A1/en
Publication of JP2023539047A publication Critical patent/JP2023539047A/ja
Publication of JP2023539047A5 publication Critical patent/JP2023539047A5/ja
Priority to JP2025204019A priority Critical patent/JP2026026191A/ja
Application granted granted Critical
Publication of JP7821160B2 publication Critical patent/JP7821160B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2023509698A 2020-08-13 2021-08-12 造血幹細胞移植関連血栓性微小血管症(hsct-tma)を処置するための抗c5抗体の用量及び投与 Active JP7821160B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025204019A JP2026026191A (ja) 2020-08-13 2025-11-26 造血幹細胞移植関連血栓性微小血管症(hsct-tma)を処置するための抗c5抗体の用量及び投与

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063065107P 2020-08-13 2020-08-13
US63/065,107 2020-08-13
PCT/US2021/045823 WO2022036151A1 (en) 2020-08-13 2021-08-12 Dosage and administration of anti-c5 antibodies for treating hematopoietic stem cell transplant-associated thrombotic microangiopathy (hsct-tma)

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025204019A Division JP2026026191A (ja) 2020-08-13 2025-11-26 造血幹細胞移植関連血栓性微小血管症(hsct-tma)を処置するための抗c5抗体の用量及び投与

Publications (3)

Publication Number Publication Date
JP2023539047A JP2023539047A (ja) 2023-09-13
JP2023539047A5 true JP2023539047A5 (https=) 2024-08-22
JP7821160B2 JP7821160B2 (ja) 2026-02-26

Family

ID=77655658

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2023509698A Active JP7821160B2 (ja) 2020-08-13 2021-08-12 造血幹細胞移植関連血栓性微小血管症(hsct-tma)を処置するための抗c5抗体の用量及び投与
JP2025204019A Pending JP2026026191A (ja) 2020-08-13 2025-11-26 造血幹細胞移植関連血栓性微小血管症(hsct-tma)を処置するための抗c5抗体の用量及び投与

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025204019A Pending JP2026026191A (ja) 2020-08-13 2025-11-26 造血幹細胞移植関連血栓性微小血管症(hsct-tma)を処置するための抗c5抗体の用量及び投与

Country Status (10)

Country Link
US (1) US20240209071A1 (https=)
EP (1) EP4196161A1 (https=)
JP (2) JP7821160B2 (https=)
KR (1) KR20230047179A (https=)
CN (1) CN116249550A (https=)
AU (1) AU2021326526B2 (https=)
CA (1) CA3173007A1 (https=)
IL (1) IL300115A (https=)
MX (1) MX2023001702A (https=)
WO (1) WO2022036151A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4583911A1 (en) 2022-09-06 2025-07-16 Alexion Pharmaceuticals, Inc. Diagnostic and prognostic biomarker profiles in patients with hematopoietic stem cell transplant-associated thrombotic microangiopathy (hsct-tma)
TW202426048A (zh) 2022-09-06 2024-07-01 美商阿雷希昂製藥公司 用於治療造血幹細胞移植相關血栓性(hsct-tma)的抗c5抗體的補充劑量和投與

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8367805B2 (en) 2004-11-12 2013-02-05 Xencor, Inc. Fc variants with altered binding to FcRn
PY09026846A (es) 2008-08-05 2015-09-01 Novartis Ag Composiciones y métodos para anticuerpos que se dirigen a la proteína de complemento c5
JP6654137B2 (ja) * 2013-09-16 2020-02-26 チルドレンズ ホスピタル メディカル センター Hsct関連血栓性微小血管症の治療のための組成物及び方法
NZ631007A (en) * 2014-03-07 2015-10-30 Alexion Pharma Inc Anti-c5 antibodies having improved pharmacokinetics
BR112017011235A2 (pt) 2014-12-19 2018-02-06 Chugai Pharmaceutical Co Ltd anticorpos anti-c5 e métodos de uso
CA3024618A1 (en) * 2016-05-27 2017-11-30 Alexion Pharmaceuticals, Inc. Methods for treatment of refractory generalized myasthenia gravis
CN116769024A (zh) 2016-06-14 2023-09-19 瑞泽恩制药公司 抗c5抗体及其用途
CN118512588A (zh) * 2017-10-26 2024-08-20 亚力兄制药公司 用于治疗阵发性夜间性血红蛋白尿(pnh)和非典型溶血性尿毒症综合征(ahus)的抗c5抗体的剂量和施用
EP3802603A1 (en) * 2018-06-04 2021-04-14 Alexion Pharmaceuticals, Inc. Dosage and administration of anti-c5 antibodies for treatment of atypical hemolytic uremic syndrome (ahus) in pediatric patients
EP4135837A1 (en) * 2020-04-16 2023-02-22 Assistance Publique, Hopitaux De Paris Methods for treating a complement mediated disorder caused by viruses

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