JP2023537958A5 - - Google Patents

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Publication number
JP2023537958A5
JP2023537958A5 JP2023509554A JP2023509554A JP2023537958A5 JP 2023537958 A5 JP2023537958 A5 JP 2023537958A5 JP 2023509554 A JP2023509554 A JP 2023509554A JP 2023509554 A JP2023509554 A JP 2023509554A JP 2023537958 A5 JP2023537958 A5 JP 2023537958A5
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JP
Japan
Prior art keywords
seq
amino acid
acid sequence
variable domain
single variable
Prior art date
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JP2023509554A
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English (en)
Japanese (ja)
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JP2023537958A (ja
JP7821159B2 (ja
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Priority claimed from PCT/CN2021/112756 external-priority patent/WO2022037527A1/zh
Publication of JP2023537958A publication Critical patent/JP2023537958A/ja
Publication of JP2023537958A5 publication Critical patent/JP2023537958A5/ja
Application granted granted Critical
Publication of JP7821159B2 publication Critical patent/JP7821159B2/ja
Active legal-status Critical Current
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JP2023509554A 2020-08-20 2021-08-16 Bcmaと結合する単一可変ドメイン及び抗原結合分子 Active JP7821159B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN202010842370 2020-08-20
CN202010842370.5 2020-08-20
PCT/CN2021/112756 WO2022037527A1 (zh) 2020-08-20 2021-08-16 结合bcma的单可变结构域及抗原结合分子

Publications (3)

Publication Number Publication Date
JP2023537958A JP2023537958A (ja) 2023-09-06
JP2023537958A5 true JP2023537958A5 (https=) 2024-08-26
JP7821159B2 JP7821159B2 (ja) 2026-02-26

Family

ID=80323410

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023509554A Active JP7821159B2 (ja) 2020-08-20 2021-08-16 Bcmaと結合する単一可変ドメイン及び抗原結合分子

Country Status (6)

Country Link
US (1) US12612635B2 (https=)
EP (1) EP4202047A4 (https=)
JP (1) JP7821159B2 (https=)
KR (1) KR20230045066A (https=)
CN (1) CN115715325A (https=)
WO (1) WO2022037527A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2024279278A1 (en) 2023-05-31 2025-12-18 Capstan Therapeutics, Inc. Lipid nanoparticle formulations and compositions
US20250127728A1 (en) 2023-10-05 2025-04-24 Capstan Therapeutics, Inc. Constrained Ionizable Cationic Lipids and Lipid Nanoparticles
WO2025076113A1 (en) 2023-10-05 2025-04-10 Capstan Therapeutics, Inc. Ionizable cationic lipids with conserved spacing and lipid nanoparticles
WO2025217452A1 (en) 2024-04-11 2025-10-16 Capstan Therapeutics, Inc. Constrained ionizable cationic lipids and lipid nanoparticles
WO2025217454A2 (en) 2024-04-11 2025-10-16 Capstan Therapeutics, Inc. Ionizable cationic lipids and lipid nanoparticles

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002066516A2 (en) * 2001-02-20 2002-08-29 Zymogenetics, Inc. Antibodies that bind both bcma and taci
EP3974453A3 (en) * 2010-11-16 2022-08-03 Amgen Inc. Agents and methods for treating diseases that correlate with bcma expression
TWI679212B (zh) * 2011-11-15 2019-12-11 美商安進股份有限公司 針對bcma之e3以及cd3的結合分子
US9243058B2 (en) * 2012-12-07 2016-01-26 Amgen, Inc. BCMA antigen binding proteins
KR102526945B1 (ko) * 2014-04-30 2023-04-27 막스-델부뤽-센트럼 퓌어 몰레쿨라레 메디친 인 데어 헬름홀츠-게마인샤프트 Cd269에 대한 인간화 항체
US10294304B2 (en) * 2015-04-13 2019-05-21 Pfizer Inc. Chimeric antigen receptors targeting B-cell maturation antigen
WO2018028647A1 (en) 2016-08-10 2018-02-15 Legend Biotech Usa Inc. Chimeric antigen receptors targeting bcma and methods of use thereof
CN111201243B (zh) * 2017-09-29 2023-08-11 财团法人牧岩生命科学研究所 对bcma具有高亲和力的抗bcma抗体和包含其的用于治疗癌症的药物组合物
KR102870868B1 (ko) 2018-06-01 2025-10-15 노파르티스 아게 Bcma에 대한 결합 분자 및 이의 용도
EP3845244A4 (en) * 2018-08-24 2022-09-07 Shenzhen Pregene Biopharma Co. Ltd. ANTI-BCMA SINGLE DOMAIN ANTIBODIES AND THEIR USE
CN109942708B (zh) * 2019-03-28 2021-01-05 上海科棋药业科技有限公司 一种抗bcma的单域抗体及其应用
CN109942709B (zh) * 2019-04-22 2019-12-27 广州百暨基因科技有限公司 一种抗bcma的单域抗体及其应用
CN111333729B (zh) * 2020-03-17 2022-12-06 深圳市南科生物工程有限公司 抗b细胞成熟抗原的纳米抗体及应用
WO2022218380A1 (zh) 2021-04-15 2022-10-20 正大天晴药业集团股份有限公司 靶向bcma的多特异性抗体

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