JP2023537870A - 肺がんを診断及び監視するためのバイオマーカー - Google Patents

肺がんを診断及び監視するためのバイオマーカー Download PDF

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Publication number
JP2023537870A
JP2023537870A JP2023506010A JP2023506010A JP2023537870A JP 2023537870 A JP2023537870 A JP 2023537870A JP 2023506010 A JP2023506010 A JP 2023506010A JP 2023506010 A JP2023506010 A JP 2023506010A JP 2023537870 A JP2023537870 A JP 2023537870A
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Prior art keywords
gene
seq
methylation
lung cancer
probe
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JP2023506010A
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English (en)
Japanese (ja)
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JP2023537870A5 (https=
Inventor
ブリアン・ロックハート
ノルウェン・ギガル－ステファン
ラウラ・ゼレブ
ヴァレリー・タリー
ピエール・ローラン－プイグ
シュファン・ワン－ルノー
エレーヌ・ブロン
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Les Laboratoires Servier SAS
Sorbonne Universite
Universite Paris Cite
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Les Laboratoires Servier SAS
Sorbonne Universite
Universite Paris Cite
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Publication of JP2023537870A publication Critical patent/JP2023537870A/ja
Publication of JP2023537870A5 publication Critical patent/JP2023537870A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2023506010A 2020-07-27 2021-07-26 肺がんを診断及び監視するためのバイオマーカー Pending JP2023537870A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP20315363.0A EP3945135A1 (en) 2020-07-27 2020-07-27 Biomarkers for diagnosing and monitoring lung cancer
EP20315363.0 2020-07-27
PCT/EP2021/070781 WO2022023233A1 (en) 2020-07-27 2021-07-26 Biomarkers for diagnosing and monitoring lung cancer

Publications (2)

Publication Number Publication Date
JP2023537870A true JP2023537870A (ja) 2023-09-06
JP2023537870A5 JP2023537870A5 (https=) 2024-07-29

Family

ID=72039477

Family Applications (1)

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JP2023506010A Pending JP2023537870A (ja) 2020-07-27 2021-07-26 肺がんを診断及び監視するためのバイオマーカー

Country Status (4)

Country Link
US (1) US20230257824A1 (https=)
EP (2) EP3945135A1 (https=)
JP (1) JP2023537870A (https=)
WO (1) WO2022023233A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115725737B (zh) * 2022-08-16 2023-09-08 山东大学 一种用于肺腺癌早期诊断的多基因甲基化试剂盒
EP4613879A1 (en) * 2022-10-31 2025-09-10 GC Genome Corporation Dna methylation marker for diagnosing lung cancer and uses thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016015948A (ja) * 2014-07-10 2016-02-01 シスメックス株式会社 肺癌に関する情報の取得方法、ならびに肺癌に関する情報を取得するためのマーカーおよびキット
CN111041095A (zh) * 2019-07-11 2020-04-21 江苏医药职业学院 检测8号染色体开放阅读框73表达水平的试剂的应用和试剂盒

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002002807A2 (en) * 2000-06-30 2002-01-10 Epigenomics Ag Diagnosis of diseases associated with cell signalling
KR101219794B1 (ko) * 2010-08-20 2013-01-10 국립암센터 Ｈｏｘａ１１유전자의 메틸화 수준을 측정하는 제제를 포함하는 비소세포폐암 진단용 조성물 및 이를 이용한 비소세포폐암 진단방법
US20180143198A1 (en) * 2014-12-26 2018-05-24 Peking University Method for detecting differentially methylated cpg islands associated with abnormal state of human body
CN109563546B (zh) * 2016-05-05 2022-09-09 精密科学发展有限责任公司 通过分析甲基化dna来检测肺肿瘤
WO2018069450A1 (en) * 2016-10-14 2018-04-19 Aarhus Universitet Methylation biomarkers for lung cancer
WO2019035100A2 (en) * 2017-08-18 2019-02-21 University Of Southern California PROGNOSTIC MARKERS OF CANCER RECIDIVE
WO2019103421A2 (ko) * 2017-11-22 2019-05-31 연세대학교 산학협력단 유전자의 cpg 메틸화 변화를 이용한 간암의 예후 또는 위험도를 평가하는 방법
JP7277460B2 (ja) * 2017-11-30 2023-05-19 マヨ ファウンデーション フォア メディカル エデュケーション アンド リサーチ 乳癌の検出
WO2020112869A1 (en) * 2018-11-27 2020-06-04 Exact Sciences Development Company, Llc Characterizing methylated dna, rna, and proteins in the detection of lung neoplasia

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016015948A (ja) * 2014-07-10 2016-02-01 シスメックス株式会社 肺癌に関する情報の取得方法、ならびに肺癌に関する情報を取得するためのマーカーおよびキット
CN111041095A (zh) * 2019-07-11 2020-04-21 江苏医药职业学院 检测8号染色体开放阅读框73表达水平的试剂的应用和试剂盒

Also Published As

Publication number Publication date
WO2022023233A9 (en) 2022-03-31
EP4189119A1 (en) 2023-06-07
WO2022023233A1 (en) 2022-02-03
EP3945135A1 (en) 2022-02-02
US20230257824A1 (en) 2023-08-17

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