JP2023537131A5 - - Google Patents

Info

Publication number
JP2023537131A5
JP2023537131A5 JP2023509663A JP2023509663A JP2023537131A5 JP 2023537131 A5 JP2023537131 A5 JP 2023537131A5 JP 2023509663 A JP2023509663 A JP 2023509663A JP 2023509663 A JP2023509663 A JP 2023509663A JP 2023537131 A5 JP2023537131 A5 JP 2023537131A5
Authority
JP
Japan
Prior art keywords
antigen
cancer
antibody
igsf8
monoclonal antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2023509663A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023537131A (ja
JP7832177B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CN2021/111469 external-priority patent/WO2022033419A2/en
Publication of JP2023537131A publication Critical patent/JP2023537131A/ja
Publication of JP2023537131A5 publication Critical patent/JP2023537131A5/ja
Priority to JP2026034828A priority Critical patent/JP2026097939A/ja
Application granted granted Critical
Publication of JP7832177B2 publication Critical patent/JP7832177B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2023509663A 2020-08-10 2021-08-09 Igsf8を標的化することによる自己免疫疾患および癌を治療するための組成物および方法 Active JP7832177B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2026034828A JP2026097939A (ja) 2020-08-10 2026-03-05 Igsf8を標的化することによる自己免疫疾患および癌を治療するための組成物および方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN2020108129 2020-08-10
CNPCT/CN2020/108129 2020-08-10
PCT/CN2021/111469 WO2022033419A2 (en) 2020-08-10 2021-08-09 Compositions and methods for treating autoimmune diseases and cancers by targeting igsf8

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2026034828A Division JP2026097939A (ja) 2020-08-10 2026-03-05 Igsf8を標的化することによる自己免疫疾患および癌を治療するための組成物および方法

Publications (3)

Publication Number Publication Date
JP2023537131A JP2023537131A (ja) 2023-08-30
JP2023537131A5 true JP2023537131A5 (enExample) 2024-08-16
JP7832177B2 JP7832177B2 (ja) 2026-03-17

Family

ID=77431086

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2023509663A Active JP7832177B2 (ja) 2020-08-10 2021-08-09 Igsf8を標的化することによる自己免疫疾患および癌を治療するための組成物および方法
JP2024507076A Pending JP2024532726A (ja) 2020-08-10 2022-08-09 Igsf8を標的化することによる自己免疫疾患および癌を治療するための組成物および方法
JP2026034828A Pending JP2026097939A (ja) 2020-08-10 2026-03-05 Igsf8を標的化することによる自己免疫疾患および癌を治療するための組成物および方法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2024507076A Pending JP2024532726A (ja) 2020-08-10 2022-08-09 Igsf8を標的化することによる自己免疫疾患および癌を治療するための組成物および方法
JP2026034828A Pending JP2026097939A (ja) 2020-08-10 2026-03-05 Igsf8を標的化することによる自己免疫疾患および癌を治療するための組成物および方法

Country Status (10)

Country Link
US (2) US20230303695A1 (enExample)
EP (2) EP4192866A2 (enExample)
JP (3) JP7832177B2 (enExample)
KR (2) KR20230077722A (enExample)
CN (2) CN116724051A (enExample)
AU (2) AU2021325225A1 (enExample)
CA (2) CA3188996A1 (enExample)
IL (2) IL300537A (enExample)
MX (2) MX2023001707A (enExample)
WO (2) WO2022033419A2 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7137696B2 (ja) 2019-05-14 2022-09-14 プロヴェンション・バイオ・インコーポレイテッド 1型糖尿病を予防するための方法および組成物
KR20230092863A (ko) 2020-06-11 2023-06-26 프로벤션 바이오, 인코포레이티드 제1형 당뇨병을 예방하기 위한 방법 및 조성물
KR20230077722A (ko) * 2020-08-10 2023-06-01 지브이20 테라퓨틱스 엘엘씨 Igsf8을 표적화하여 자가면역 질환 및 암을 치료하기 위한 조성물 및 방법
MX2023013851A (es) 2021-05-24 2023-12-08 Provention Bio Inc Metodos para el tratamiento de diabetes tipo 1.
WO2025251015A1 (en) * 2024-05-30 2025-12-04 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Pan-gi norovirus monoclonal antibody and its use

Family Cites Families (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
GB8823869D0 (en) 1988-10-12 1988-11-16 Medical Res Council Production of antibodies
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US6673986B1 (en) 1990-01-12 2004-01-06 Abgenix, Inc. Generation of xenogeneic antibodies
US6713610B1 (en) 1990-01-12 2004-03-30 Raju Kucherlapati Human antibodies derived from immunized xenomice
US5877397A (en) 1990-08-29 1999-03-02 Genpharm International Inc. Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
US5874299A (en) 1990-08-29 1999-02-23 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
US6300129B1 (en) 1990-08-29 2001-10-09 Genpharm International Transgenic non-human animals for producing heterologous antibodies
US6255458B1 (en) 1990-08-29 2001-07-03 Genpharm International High affinity human antibodies and human antibodies against digoxin
US5545806A (en) 1990-08-29 1996-08-13 Genpharm International, Inc. Ransgenic non-human animals for producing heterologous antibodies
US6342220B1 (en) 1997-08-25 2002-01-29 Genentech, Inc. Agonist antibodies
AU6366999A (en) 1998-10-30 2000-05-22 Takeda Chemical Industries Ltd. Betacellulin protein-containing preparations
US6900292B2 (en) 2001-08-17 2005-05-31 Lee-Hwei K. Sun Fc fusion proteins of human erythropoietin with increased biological activities
KR100976076B1 (ko) 2003-05-22 2010-08-17 아보트 러보러터리즈 인다졸, 벤즈이속사졸 및 벤즈이소티아졸 키나제 억제제
DK1678314T3 (da) 2003-10-22 2012-12-03 Keck Graduate Inst Fremgangsmåde til syntetisering af heteromultimere polypeptider i gær ved anvendelse af en haploid parringsstrategi
TWI309240B (en) 2004-09-17 2009-05-01 Hoffmann La Roche Anti-ox40l antibodies
WO2006076288A2 (en) 2005-01-11 2006-07-20 Five Prime Therapeutics, Inc. Dna constructs for long-term expression of intravascularly injected naked dna
WO2006081430A2 (en) 2005-01-27 2006-08-03 Five Prime Therapeutics, Inc. Leader sequences for directing secretion of polypeptides and methods for production thereof
JP5238936B2 (ja) 2005-03-25 2013-07-17 ジーアイティーアール,インク. Gitr結合分子およびその使用
DK1879573T3 (da) 2005-05-10 2013-02-25 Incyte Corp Modulatorer af indolamin 2,3-dioxygenase og fremgangsmåder til anvendelse deraf
KR101704734B1 (ko) 2005-07-01 2017-02-09 이. 알. 스퀴부 앤드 선즈, 엘.엘.씨. 예정 사멸 리간드 1 (피디-엘1)에 대한 인간 모노클로날 항체
ES2540561T3 (es) 2005-12-20 2015-07-10 Incyte Corporation N-hidroxiamidinoheterociclos como moduladores de indolamina 2,3-dioxigenasa
CA2663057C (en) 2006-09-19 2015-12-08 Incyte Corporation N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase
CL2007002650A1 (es) 2006-09-19 2008-02-08 Incyte Corp Compuestos derivados de heterociclo n-hidroxiamino; composicion farmaceutica, util para tratar cancer, infecciones virales y desordenes neurodegenerativos entre otras.
EP1987839A1 (en) 2007-04-30 2008-11-05 I.N.S.E.R.M. Institut National de la Sante et de la Recherche Medicale Cytotoxic anti-LAG-3 monoclonal antibody and its use in the treatment or prevention of organ transplant rejection and autoimmune disease
PT2175884T (pt) 2007-07-12 2016-09-21 Gitr Inc Terapias de combinação empregando moléculas de ligação a gitr
US7981415B2 (en) 2007-09-07 2011-07-19 Cisthera, Inc. Humanized PAI-1 antibodies
EP2044949A1 (en) 2007-10-05 2009-04-08 Immutep Use of recombinant lag-3 or the derivatives thereof for eliciting monocyte immune response
WO2009073620A2 (en) 2007-11-30 2009-06-11 Newlink Genetics Ido inhibitors
AR072999A1 (es) 2008-08-11 2010-10-06 Medarex Inc Anticuerpos humanos que se unen al gen 3 de activacion linfocitaria (lag-3) y los usos de estos
MX356367B (es) 2008-12-09 2018-05-25 Genentech Inc Anticuerpos anti-pd-l1 y su uso para mejorar la funcion de celulas t.
IN2015DN02826A (enExample) 2009-09-03 2015-09-11 Merck Sharp & Dohme
WO2011130417A2 (en) * 2010-04-15 2011-10-20 Amgen Inc. HUMAN FGF RECEPTOR AND β-KLOTHO BINDING PROTEINS
NZ729044A (en) 2010-09-09 2020-07-31 Pfizer 4-1bb binding molecules
NO2694640T3 (enExample) 2011-04-15 2018-03-17
CA2833636A1 (en) 2011-04-20 2012-10-26 Amplimmune, Inc. Antibodies and other molecules that bind b7-h1 and pd-1
BR112014012819B1 (pt) 2011-11-28 2022-08-16 Merck Patent Gmbh Anticorpo anti-pd-l1 ou fragmento de ligação ao antígeno do mesmo e composição
MX356337B (es) 2011-12-15 2018-05-23 Hoffmann La Roche Anticuerpos contra csf-1r humano y sus usos.
MX2014008961A (es) 2012-02-06 2014-10-14 Genentech Inc Composiciones y metodos para utilizar inhibidores de csf1r.
AR090263A1 (es) 2012-03-08 2014-10-29 Hoffmann La Roche Terapia combinada de anticuerpos contra el csf-1r humano y las utilizaciones de la misma
KR20150018533A (ko) 2012-05-11 2015-02-23 파이브 프라임 테라퓨틱스, 인크. 콜로니 자극 인자 1 수용체(csf1r)에 결속하는 항체들에 의한 질병 상태의 치료 방법
AR091649A1 (es) 2012-07-02 2015-02-18 Bristol Myers Squibb Co Optimizacion de anticuerpos que se fijan al gen de activacion de linfocitos 3 (lag-3) y sus usos
CN107759690A (zh) 2012-08-31 2018-03-06 戊瑞治疗有限公司 用结合群落刺激因子1受体(csf1r)的抗体治疗病状的方法
TW201605896A (zh) 2013-08-30 2016-02-16 安美基股份有限公司 Gitr抗原結合蛋白
PT3370768T (pt) * 2015-11-03 2022-04-21 Janssen Biotech Inc Anticorpos que se ligam especificamente ao pd-1 e seus usos
EP3401332A1 (en) * 2017-05-08 2018-11-14 MAB Discovery GmbH Anti-il-1r3 antibodies for use in inflammatory conditions
BR112020007751A2 (pt) * 2017-10-25 2020-10-20 Acceleron Pharma Inc. proteínas de ligação de alk7 e usos das mesmas
KR102163305B1 (ko) * 2017-11-16 2020-10-08 오름테라퓨틱 주식회사 세포의 세포질에 침투하여 세포내 활성화된 Ras를 억제하는 항체 및 이의 용도
TW202135861A (zh) * 2019-12-25 2021-10-01 中國大陸商上海尋百會生物科技有限公司 藉由靶向igsf8以治療自體免疫疾病及癌症之組合物及方法
KR20230077722A (ko) * 2020-08-10 2023-06-01 지브이20 테라퓨틱스 엘엘씨 Igsf8을 표적화하여 자가면역 질환 및 암을 치료하기 위한 조성물 및 방법

Similar Documents

Publication Publication Date Title
US11942149B2 (en) Bispecific binding molecules that are capable of binding CD137 and tumor antigens, and uses thereof
Singh et al. Monoclonal antibodies: a review
US20250171558A1 (en) HUMAN IgG Fc DOMAIN VARIANTS WITH IMPROVED EFFECTOR FUNCTION
US20210371544A1 (en) Low-viscosity antigen binding proteins and methods of making them
US11119096B2 (en) Universal assay for determining the quantity of therapeutic monoclonal antibodies and their corresponding anti-drug-antibodies in samples
JP2024532726A5 (enExample)
AU2018246873A1 (en) ErbB-2 and ErbB3 binding bispecific antibodies for use in the treatment f cells that have an NRG1 fusion gene
US12098214B2 (en) Combination therapies for treating cancer
US12435155B2 (en) CD137 binding molecules and uses thereof
CN116724051A (zh) 用于通过靶向igsf8来治疗自身免疫性疾病和癌症的组合物和方法
US20240307548A1 (en) Enhanced targeting using antibody-oligonucleotide conjugates
JP2024508886A5 (enExample)
CN115397851B (zh) Cxcl10结合蛋白及其用途
EA046873B1 (ru) Cd137-связывающие молекулы и варианты их применения
OA19914A (en) Human IgG Fc domain variants with improved effector function.