JP2023530889A5 - - Google Patents
Info
- Publication number
- JP2023530889A5 JP2023530889A5 JP2022575771A JP2022575771A JP2023530889A5 JP 2023530889 A5 JP2023530889 A5 JP 2023530889A5 JP 2022575771 A JP2022575771 A JP 2022575771A JP 2022575771 A JP2022575771 A JP 2022575771A JP 2023530889 A5 JP2023530889 A5 JP 2023530889A5
- Authority
- JP
- Japan
- Prior art keywords
- analyte
- signal
- oligonucleotides
- specific
- nucleotide sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EPPCT/EP2020/067010 | 2020-06-18 | ||
| PCT/EP2020/067010 WO2020254519A1 (en) | 2019-06-18 | 2020-06-18 | Method of signal encoding of analytes in a sample |
| US202063127910P | 2020-12-18 | 2020-12-18 | |
| US63/127,910 | 2020-12-18 | ||
| US202063129942P | 2020-12-23 | 2020-12-23 | |
| US63/129,942 | 2020-12-23 | ||
| PCT/EP2021/066668 WO2021255263A2 (en) | 2020-06-18 | 2021-06-18 | Multiplex method for detecting different analytes and different subgroups/variations of an analyte in a sample |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023530889A JP2023530889A (ja) | 2023-07-20 |
| JP2023530889A5 true JP2023530889A5 (enExample) | 2024-06-12 |
| JP7828901B2 JP7828901B2 (ja) | 2026-03-12 |
Family
ID=79268536
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022575771A Active JP7828901B2 (ja) | 2020-06-18 | 2021-06-18 | 試料中の異なる分析物及び分析物の異なるサブグループ／変形物を検出するための多重的方法 |
| JP2022575762A Pending JP2023529682A (ja) | 2020-06-18 | 2021-06-18 | 試料中の異なる分析物を検出するための多重的方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022575762A Pending JP2023529682A (ja) | 2020-06-18 | 2021-06-18 | 試料中の異なる分析物を検出するための多重的方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US20240279736A1 (enExample) |
| EP (2) | EP4168575A1 (enExample) |
| JP (2) | JP7828901B2 (enExample) |
| KR (2) | KR20230023647A (enExample) |
| CN (2) | CN115702249A (enExample) |
| AU (2) | AU2021294274A1 (enExample) |
| CA (2) | CA3181725A1 (enExample) |
| WO (2) | WO2021255244A1 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7828901B2 (ja) * | 2020-06-18 | 2026-03-12 | リゾルブ バイオサイエンシズ ゲゼルシャフト ミット ベシュレンクテル ハフツング | 試料中の異なる分析物及び分析物の異なるサブグループ／変形物を検出するための多重的方法 |
| DE102022131449A1 (de) | 2022-11-28 | 2024-05-29 | Carl Zeiss Microscopy Gmbh | Verfahren und Vorrichtung zum Aufbereiten von Daten zum Identifizieren von Analyten |
| DE102022131447A1 (de) | 2022-11-28 | 2024-05-29 | Carl Zeiss Microscopy Gmbh | Verfahren und Vorrichtung zum Aufbereiten von Daten zum Identifizieren von Analyten |
| DE102022131451A1 (de) | 2022-11-28 | 2024-05-29 | Carl Zeiss Microscopy Gmbh | Verfahren und Vorrichtung zum Bestimmen einer Signal-Zusammensetzung von Signalfolgen einer Bildfolge |
| DE102022131446A1 (de) | 2022-11-28 | 2024-05-29 | Carl Zeiss Microscopy Gmbh | Verfahren und Vorrichtung zum Aufbereiten von Daten zum Identifizieren von Analyten |
| DE102022131442A1 (de) | 2022-11-28 | 2024-05-29 | Carl Zeiss Microscopy Gmbh | Verfahren und Vorrichtung zum Zuordnen von Bildbereichen einer Bildfolge zu Ergebnisklassen mittels eines Analytdaten-Auswertesystems mit einem Verarbeitungsmodells |
| DE102022131448A1 (de) | 2022-11-28 | 2024-05-29 | Carl Zeiss Microscopy Gmbh | Verfahren und Vorrichtung zum Aufbereiten von Daten zum Identifizieren von Analyten |
| DE102022131441A1 (de) | 2022-11-28 | 2024-05-29 | Carl Zeiss Microscopy Gmbh | Verfahren und Vorrichtung zum Aufbereiten von Daten zum Identifizieren von Analyten |
| DE102022131450A1 (de) | 2022-11-28 | 2024-05-29 | Carl Zeiss Microscopy Gmbh | Verfahren und Vorrichtung zum Aufbereiten von Daten zum Identifizieren von Analyten |
| DE102022131444A1 (de) | 2022-11-28 | 2024-05-29 | Carl Zeiss Microscopy Gmbh | Verfahren zum Identifizieren von Analyten in einer Bildfolge |
| DE102022131445A1 (de) | 2022-11-28 | 2024-05-29 | Carl Zeiss Microscopy Gmbh | Verfahren und Vorrichtung zum Aufbereiten von Daten zum Identifizieren von Analyten |
| AU2024229355A1 (en) * | 2023-03-01 | 2025-09-04 | Resolve Biosciences Gmbh | Complex formation for parallel detection of multiple analytes in multiple applications |
| WO2024256715A1 (en) * | 2023-06-16 | 2024-12-19 | Resolve Biosciences Gmbh | Reagent for in situ hybridization quality control |
| DE102023122213A1 (de) | 2023-08-18 | 2025-02-20 | Carl Zeiss Microscopy Gmbh | Verfahren zum Bereitstellen von Quelldaten zum Trainieren oder Validieren eines Verarbeitungsmodells zum Verarbeiten von Analyt-Bildfolgen |
| WO2025093690A1 (en) | 2023-11-02 | 2025-05-08 | Resolve Biosciences Gmbh | Method for preparing tissue sections |
| WO2025099313A1 (en) | 2023-11-10 | 2025-05-15 | Resolve Biosciences Gmbh | Reducing background fluorescence in single molecule fluorescence in situ hybridization applications |
| WO2025125442A1 (en) * | 2023-12-13 | 2025-06-19 | Resolve Biosciences Gmbh | High resolution multiplex method for detecting at least two targets |
| WO2025132546A1 (en) | 2023-12-19 | 2025-06-26 | Resolve Biosciences Gmbh | Method for reducing nonspecific signals in in-situ hybridization assays |
| WO2025250686A1 (en) * | 2024-05-28 | 2025-12-04 | The Regents Of The University Of California | Methods and systems for parallel spatially resolved single-cell profiling |
| WO2026037951A1 (en) | 2024-08-16 | 2026-02-19 | Resolve Biosciences Gmbh | Compositions and methods for spatial analysis of multicell suspensions |
| WO2026068813A1 (en) | 2024-09-30 | 2026-04-02 | Resolve Biosciences Gmbh | Immuno-oncology gene panel compositions and methods of making and use thereof |
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| CA1228811A (en) | 1983-05-05 | 1987-11-03 | Robert G. Pergolizzi | Assay method utilizing polynucleotide sequences |
| US6627159B1 (en) | 2000-06-28 | 2003-09-30 | 3M Innovative Properties Company | Centrifugal filling of sample processing devices |
| US6734401B2 (en) | 2000-06-28 | 2004-05-11 | 3M Innovative Properties Company | Enhanced sample processing devices, systems and methods |
| WO2003016574A1 (en) | 2001-08-16 | 2003-02-27 | Zhifeng Shao | Analysis of gene expression profiles using sequential hybridization |
| CA2480673A1 (en) | 2002-03-29 | 2003-10-09 | Genentech, Inc. | Methods and compositions for detection and quantitation of nucleic acid analytes |
| EP3042963A1 (en) | 2005-06-20 | 2016-07-13 | Advanced Cell Diagnostics, Inc. | Methods of detecting nucleic acids in individual cells and of identifying rare cells from large heterogeneous cell populations |
| WO2011038403A1 (en) | 2009-09-28 | 2011-03-31 | Yuling Luo | Methods of detecting nucleic acid sequences with high specificity |
| US9677125B2 (en) | 2009-10-21 | 2017-06-13 | General Electric Company | Detection of plurality of targets in biological samples |
| US10267808B2 (en) | 2010-03-08 | 2019-04-23 | California Institute Of Technology | Molecular indicia of cellular constituents and resolving the same by super-resolution technologies in single cells |
| CN101895587B (zh) | 2010-07-06 | 2015-09-16 | 中兴通讯股份有限公司 | 防止用户私自修改ip地址的方法、装置和系统 |
| EP2794928B1 (en) | 2011-12-22 | 2019-02-20 | President and Fellows of Harvard College | Compositions and methods for analyte detection |
| ES2991004T3 (es) | 2011-12-22 | 2024-12-02 | Harvard College | Métodos para la detección de analitos |
| JP6096885B2 (ja) | 2012-04-19 | 2017-03-15 | シージーン アイエヌシー | ＰＴＯ切断及び伸長依存的なシグナリングオリゴヌクレオチド切断を用いたターゲット核酸配列の検出｛ＤｅｔｅｃｔｉｏｎｏｆＴａｒｇｅｔＮｕｃｌｅｉｃＡｃｉｄＳｅｑｕｅｎｃｅｂｙＰＴＯＣｌｅａｖａｇｅａｎｄＥｘｔｅｎｓｉｏｎ−ＤｅｐｅｎｄｅｎｔＳｉｇｎａｌｉｎｇＯｌｉｇｏｎｕｃｌｅｏｔｉｄｅＣｌｅａｖａｇｅ｝ |
| US10510435B2 (en) * | 2013-04-30 | 2019-12-17 | California Institute Of Technology | Error correction of multiplex imaging analysis by sequential hybridization |
| KR102368591B1 (ko) | 2013-04-30 | 2022-02-25 | 캘리포니아 인스티튜트 오브 테크놀로지 | 순차적 하이브리드화 바코딩에 의한 분자의 멀티플렉스 표지화 |
| US20160369329A1 (en) | 2013-04-30 | 2016-12-22 | California Institute Of Technology | Multiplex labeling of molecules by sequential hybridization barcoding using probes with cleavable linkers |
| US20150105298A1 (en) | 2013-10-10 | 2015-04-16 | The Research Foundation For The State University Of New York | Multi-oligomer in situ hybridization probes |
| EP3169810B1 (en) | 2014-07-17 | 2024-09-04 | California Institute of Technology | Multiplex analysis of molecules in single cells by image correlation |
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| CA3032649A1 (en) * | 2016-08-01 | 2018-02-08 | California Institute Of Technology | Sequential probing of molecular targets based on pseudo-color barcodes with embedded error correction mechanism |
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| CN111699268B (zh) * | 2017-12-08 | 2024-04-26 | 加州理工学院 | 通过用探针的快速切换和再杂交进行顺序杂交编条形码来多重标记分子 |
| KR102893736B1 (ko) | 2018-05-14 | 2025-11-28 | 브루커 스페이셜 바이올로지, 인크. | 화학 조성물 및 이의 사용 방법 |
| JP2022506518A (ja) | 2018-11-01 | 2022-01-17 | カリフォルニア インスティチュート オブ テクノロジー | 高速広視野共焦点イメージング用のマルチチャネルラインスキャナ |
| US11421273B2 (en) | 2018-12-03 | 2022-08-23 | California Institute Of Technology | In situ readout of DNA barcodes |
| CA3122569A1 (en) | 2018-12-13 | 2020-06-18 | President And Fellows Of Harvard College | Amplification methods and systems for merfish and other applications |
| US20220128565A1 (en) | 2019-02-04 | 2022-04-28 | Akoya Biosciences, Inc. | Analyte detection by selective labeling of biological samples |
| CN119220641A (zh) | 2019-05-31 | 2024-12-31 | 10X基因组学有限公司 | 检测目标核酸分子的方法 |
| CA3146081A1 (en) | 2019-07-30 | 2021-02-04 | Huy Quoc NGUYEN | Methods and compositions related to target analysis |
| CN114729391A (zh) | 2019-09-30 | 2022-07-08 | 阿科亚生物科学股份有限公司 | 用酶介导的放大的多路复用成像 |
| EP4065728A1 (en) | 2019-11-25 | 2022-10-05 | California Institute of Technology | Quantitative analysis of single-cell proteins by identification and quantification separation (duet) |
| CA3158080A1 (en) | 2019-11-26 | 2021-06-03 | Huy Quoc NGUYEN | Compositions, sets, and methods related to target analysis |
| CN115176027A (zh) | 2019-12-12 | 2022-10-11 | 哈佛大学校长及研究员协会 | 用于光指导的生物分子条形码化的组合物和方法 |
| WO2021247618A1 (en) | 2020-06-02 | 2021-12-09 | 10X Genomics, Inc. | Enrichment of nucleic acid sequences |
| JP7828901B2 (ja) * | 2020-06-18 | 2026-03-12 | リゾルブ バイオサイエンシズ ゲゼルシャフト ミット ベシュレンクテル ハフツング | 試料中の異なる分析物及び分析物の異なるサブグループ／変形物を検出するための多重的方法 |
| US20210395804A1 (en) | 2020-06-19 | 2021-12-23 | California Institute Of Technology | Sensitive and multiplexed detection of nucleic acids and proteins for large scale serological testing |
-
2021
- 2021-06-18 JP JP2022575771A patent/JP7828901B2/ja active Active
- 2021-06-18 US US18/001,930 patent/US20240279736A1/en active Pending
- 2021-06-18 EP EP21732086.0A patent/EP4168575A1/en active Pending
- 2021-06-18 US US18/001,933 patent/US12492427B2/en active Active
- 2021-06-18 WO PCT/EP2021/066620 patent/WO2021255244A1/en not_active Ceased
- 2021-06-18 AU AU2021294274A patent/AU2021294274A1/en active Pending
- 2021-06-18 EP EP21733989.4A patent/EP4168576A2/en active Pending
- 2021-06-18 JP JP2022575762A patent/JP2023529682A/ja active Pending
- 2021-06-18 CN CN202180041893.2A patent/CN115702249A/zh active Pending
- 2021-06-18 KR KR1020227043398A patent/KR20230023647A/ko active Pending
- 2021-06-18 KR KR1020227043397A patent/KR20230023646A/ko active Pending
- 2021-06-18 CN CN202180041889.6A patent/CN115698322A/zh active Pending
- 2021-06-18 CA CA3181725A patent/CA3181725A1/en active Pending
- 2021-06-18 WO PCT/EP2021/066668 patent/WO2021255263A2/en not_active Ceased
- 2021-06-18 AU AU2021291051A patent/AU2021291051A1/en active Pending
- 2021-06-18 CA CA3181737A patent/CA3181737A1/en active Pending
- 2021-12-17 US US17/554,093 patent/US12442037B2/en active Active
-
2025
- 2025-11-03 US US19/377,307 patent/US20260234705A1/en active Pending
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