JP2023529926A5 - - Google Patents
Info
- Publication number
- JP2023529926A5 JP2023529926A5 JP2022576040A JP2022576040A JP2023529926A5 JP 2023529926 A5 JP2023529926 A5 JP 2023529926A5 JP 2022576040 A JP2022576040 A JP 2022576040A JP 2022576040 A JP2022576040 A JP 2022576040A JP 2023529926 A5 JP2023529926 A5 JP 2023529926A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- group
- optionally substituted
- groups
- independently selected
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2008749.0 | 2020-06-09 | ||
| GBGB2008749.0A GB202008749D0 (en) | 2020-06-09 | 2020-06-09 | Novel compounds |
| PCT/GB2021/051428 WO2021250399A1 (en) | 2020-06-09 | 2021-06-09 | 4-ethynylpyridine derivatives useful as gcn2 inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023529926A JP2023529926A (ja) | 2023-07-12 |
| JP2023529926A5 true JP2023529926A5 (https=) | 2025-12-04 |
Family
ID=71616023
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022576040A Pending JP2023529926A (ja) | 2020-06-09 | 2021-06-09 | Ｇｃｎ２阻害剤として有用な４－エチニルピリジン誘導体 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20230271939A1 (https=) |
| EP (1) | EP4161915A1 (https=) |
| JP (1) | JP2023529926A (https=) |
| KR (1) | KR20230058042A (https=) |
| CN (2) | CN116113629B (https=) |
| AU (1) | AU2021289535A1 (https=) |
| BR (1) | BR112022025147A2 (https=) |
| CA (1) | CA3181909A1 (https=) |
| GB (1) | GB202008749D0 (https=) |
| IL (1) | IL298860B1 (https=) |
| MX (1) | MX2022015516A (https=) |
| WO (1) | WO2021250399A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB202008749D0 (en) | 2020-06-09 | 2020-07-22 | Ip2Ipo Innovations Ltd | Novel compounds |
| GB202104635D0 (en) | 2021-03-31 | 2021-05-12 | Imperial College Innovations Ltd | Methods and compositions for identifying and treating GCN2-dependent cancers |
| GB202118096D0 (en) * | 2021-12-14 | 2022-01-26 | Ip2Ipo Innovations Ltd | Novel compounds |
| GB202403113D0 (en) | 2024-03-04 | 2024-04-17 | Apollo Ap30 Ltd | Novel compounds |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7037927B2 (en) | 2003-10-16 | 2006-05-02 | Abbott Laboratories | Amides that inhibit vanilloid receptor subtype 1 (VR1) receptor |
| US20080146599A1 (en) | 2005-02-01 | 2008-06-19 | Astrazeneca Ab | Pyrimidine Compounds Having Tie-2 (Tek) Inhibitory Activity |
| GB0502418D0 (en) | 2005-02-05 | 2005-03-16 | Astrazeneca Ab | Compounds |
| US8546413B2 (en) | 2009-06-15 | 2013-10-01 | Nerviano Medical Sciences S.R.L. | Substituted pyrimidinylpyrrolopyridinone derivatives, process for their preparation and their use as kinase inhibitors |
| ES2655264T3 (es) | 2012-01-28 | 2018-02-19 | Merck Patent Gmbh | Derivados de triazolo[4,5-d]pirimidina |
| US20150051202A1 (en) | 2012-03-07 | 2015-02-19 | Merck Patent Gmbh | Triazolopyrazine derivatives |
| WO2014031928A2 (en) | 2012-08-24 | 2014-02-27 | Philip Jones | Heterocyclic modulators of hif activity for treatment of disease |
| ES2755772T3 (es) | 2012-11-07 | 2020-04-23 | Nerviano Medical Sciences Srl | Pirimidinil y piridinilpirrolopiridinonas sustituidas, proceso para su preparación y su uso como inhibidores de cinasas |
| EP2964648B1 (en) | 2013-03-05 | 2016-11-16 | Merck Patent GmbH | 9-(aryl or heteroaryl)-2-(pyrazolyl, pyrrolidinyl or cyclopentyl)aminopurine derivatives as anticancer agents |
| AU2014224975B2 (en) | 2013-03-05 | 2017-09-14 | Merck Patent Gmbh | Triazolo(4,5-d)pyrimidine derivatives for the treatment of diseases such as cancer |
| CN105732614B (zh) | 2014-12-09 | 2018-06-12 | 中国科学院广州生物医药与健康研究院 | 磺酰胺基芳基炔类化合物及其用途 |
| CN104829613B (zh) | 2015-04-13 | 2020-06-09 | 赤峰蒙广生物科技有限公司 | 二芳基取代的吡唑并环类衍生物、其制备方法及其在医药领域的应用 |
| HRP20241768T1 (hr) * | 2016-08-10 | 2025-02-28 | Takeda Pharmaceutical Company Limited | Heterociklički spoj |
| CN108473476B (zh) | 2016-10-13 | 2021-02-19 | 深圳市塔吉瑞生物医药有限公司 | 用于抑制蛋白激酶活性的炔基杂环类化合物 |
| JP7229257B2 (ja) | 2018-01-29 | 2023-02-28 | メルク パテント ゲーエムベーハー | Ｇｃｎ２阻害剤およびその使用 |
| BR112020015396A2 (pt) | 2018-01-29 | 2020-12-08 | Merck Patent Gmbh | Inididores de gcn2 e usos dos mesmos |
| EP3802544A1 (en) | 2018-06-05 | 2021-04-14 | RAPT Therapeutics, Inc. | Pyrazolo-pyrimidin-amino-cycloalkyl compounds and their therapeutic uses |
| US20220388964A1 (en) | 2019-04-12 | 2022-12-08 | Hibercell, Inc. | (aza)indazolyl-aryl sulfonamide and related compounds and their use in treating medical conditions |
| WO2021155253A1 (en) | 2020-01-31 | 2021-08-05 | Atomwise Inc. | Anat inhibitors and methods of use thereof |
| JP2023514328A (ja) | 2020-02-17 | 2023-04-05 | アレスタ・セラピューティクス・ベスローテン・フェンノートシャップ | Ｇｃｎ２モジュレーター化合物 |
| WO2021222147A1 (en) | 2020-04-27 | 2021-11-04 | Hibercell, Inc. | Heterocyclic gcn2 modulators |
| GB202008749D0 (en) | 2020-06-09 | 2020-07-22 | Ip2Ipo Innovations Ltd | Novel compounds |
| IL302807A (en) | 2020-11-18 | 2023-07-01 | Deciphera Pharmaceuticals Llc | Gcn2 and perk kinase inhibitors and methods of use thereof |
| BR112023014723A2 (pt) | 2021-01-22 | 2023-10-03 | Hibercell Inc | Compostos moduladores de gcn2 e usos dos mesmos |
| US20240150345A1 (en) | 2021-01-22 | 2024-05-09 | Hibercell, Inc. | Gcn2 modulating compounds and uses thereof |
-
2020
- 2020-06-09 GB GBGB2008749.0A patent/GB202008749D0/en not_active Ceased
-
2021
- 2021-06-09 EP EP21735355.6A patent/EP4161915A1/en active Pending
- 2021-06-09 WO PCT/GB2021/051428 patent/WO2021250399A1/en not_active Ceased
- 2021-06-09 US US18/001,317 patent/US20230271939A1/en active Pending
- 2021-06-09 KR KR1020237000394A patent/KR20230058042A/ko active Pending
- 2021-06-09 MX MX2022015516A patent/MX2022015516A/es unknown
- 2021-06-09 JP JP2022576040A patent/JP2023529926A/ja active Pending
- 2021-06-09 IL IL298860A patent/IL298860B1/en unknown
- 2021-06-09 BR BR112022025147A patent/BR112022025147A2/pt unknown
- 2021-06-09 CA CA3181909A patent/CA3181909A1/en active Pending
- 2021-06-09 CN CN202180058556.4A patent/CN116113629B/zh active Active
- 2021-06-09 CN CN202411827368.5A patent/CN119661503A/zh active Pending
- 2021-06-09 AU AU2021289535A patent/AU2021289535A1/en active Pending
-
2023
- 2023-03-28 US US18/191,772 patent/US11945799B2/en active Active
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