JP2023529417A5 - - Google Patents
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- Publication number
- JP2023529417A5 JP2023529417A5 JP2022575373A JP2022575373A JP2023529417A5 JP 2023529417 A5 JP2023529417 A5 JP 2023529417A5 JP 2022575373 A JP2022575373 A JP 2022575373A JP 2022575373 A JP2022575373 A JP 2022575373A JP 2023529417 A5 JP2023529417 A5 JP 2023529417A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- acid sequence
- amino acid
- sequence shown
- antigen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063038957P | 2020-06-15 | 2020-06-15 | |
| US63/038,957 | 2020-06-15 | ||
| PCT/US2021/037314 WO2021257497A1 (en) | 2020-06-15 | 2021-06-15 | Adeno-associated virus antibodies and fragments thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023529417A JP2023529417A (ja) | 2023-07-10 |
| JP2023529417A5 true JP2023529417A5 (https=) | 2024-06-19 |
| JP7785023B2 JP7785023B2 (ja) | 2025-12-12 |
Family
ID=77398628
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022575373A Active JP7785023B2 (ja) | 2020-06-15 | 2021-06-15 | アデノ関連ウイルス抗体及びそのフラグメント |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US12391745B2 (https=) |
| EP (1) | EP4165076A1 (https=) |
| JP (1) | JP7785023B2 (https=) |
| WO (1) | WO2021257497A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3596112A2 (en) | 2017-03-17 | 2020-01-22 | Newcastle University | Adeno-associated virus vector delivery of a fragment of micro-dystrophin to treat muscular dystrophy |
| MY208145A (en) | 2018-06-18 | 2025-04-18 | Res Inst Nationwide Childrens Hospital | Adeno-associated virus vector delivery of muscle specific micro-dystrophin to treat muscular dystrophy |
| US12391745B2 (en) | 2020-06-15 | 2025-08-19 | Sarepta Therapeutics, Inc. | Adeno-associated virus antibodies and fragments thereof |
| WO2023196892A1 (en) | 2022-04-06 | 2023-10-12 | The Trustees Of The University Of Pennsylvania | Passive immunization with anti- aav neutralizing antibodies to prevent off-target transduction of intrathecally delivered aav vectors |
| WO2024140627A1 (zh) * | 2022-12-26 | 2024-07-04 | 南京金斯瑞生物科技有限公司 | 抗多种血清型aav衣壳蛋白的单克隆抗体及其制备方法和用途 |
| EP4705768A1 (en) * | 2023-05-05 | 2026-03-11 | Regeneron Pharmaceuticals, Inc. | Labeling and anti-drug antibody assays for aav vectors |
| CN116751284B (zh) * | 2023-06-13 | 2024-06-04 | 康元医疗科技(大连)有限公司 | 一种纳米抗体、包含该纳米抗体的多肽及其应用 |
| WO2025083119A1 (en) * | 2023-10-18 | 2025-04-24 | Svar Life Science Ab | Assessment of aav-mediated complement activation potential |
| WO2025100417A1 (ja) * | 2023-11-06 | 2025-05-15 | 株式会社ダイセル | Ａａｖのフルカプシドに対するアフィニティポリペプチド |
| CN117229393B (zh) * | 2023-11-10 | 2024-01-30 | 北京百普赛斯生物科技股份有限公司 | 特异性结合腺相关病毒5的抗体及其应用 |
| WO2026069251A1 (en) * | 2024-09-30 | 2026-04-02 | Sarepta Therapeutics, Inc. | Adeno-associated virus capsid antibodies and fragments thereof |
| CN119080918A (zh) * | 2024-10-11 | 2024-12-06 | 杭州艾策生物技术有限公司 | 一种包含aav-x抗原结合结构域的结合蛋白 |
| CN120314575B (zh) * | 2025-06-16 | 2025-08-29 | 重庆原伦生物科技有限公司 | 一种利用双抗体夹心定量检测PreScission蛋白酶含量的方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4879231A (en) | 1984-10-30 | 1989-11-07 | Phillips Petroleum Company | Transformation of yeasts of the genus pichia |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| GB8610600D0 (en) | 1986-04-30 | 1986-06-04 | Novo Industri As | Transformation of trichoderma |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| EP0402226A1 (en) | 1989-06-06 | 1990-12-12 | Institut National De La Recherche Agronomique | Transformation vectors for yeast yarrowia |
| US5814318A (en) * | 1990-08-29 | 1998-09-29 | Genpharm International Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US9434928B2 (en) | 2011-11-23 | 2016-09-06 | Nationwide Children's Hospital, Inc. | Recombinant adeno-associated virus delivery of alpha-sarcoglycan polynucleotides |
| MX367100B (es) * | 2012-02-17 | 2019-08-05 | The Children´S Hospital Of Philadelphia | Composiciones del vector aav y metodos para su transferencia genetica a celulas, organos y tejidos. |
| US20180179265A1 (en) | 2015-04-27 | 2018-06-28 | The Trustees Of The University Of Pennsylvania | Engineered human anti-aav antibodies and uses thereof |
| WO2017078839A1 (en) * | 2015-11-02 | 2017-05-11 | Bioatla, Llc | Conditionally active polypeptides |
| US12391745B2 (en) | 2020-06-15 | 2025-08-19 | Sarepta Therapeutics, Inc. | Adeno-associated virus antibodies and fragments thereof |
-
2021
- 2021-06-15 US US17/348,356 patent/US12391745B2/en active Active
- 2021-06-15 EP EP21756088.7A patent/EP4165076A1/en active Pending
- 2021-06-15 WO PCT/US2021/037314 patent/WO2021257497A1/en not_active Ceased
- 2021-06-15 JP JP2022575373A patent/JP7785023B2/ja active Active
- 2021-09-17 US US17/478,645 patent/US11472866B2/en active Active
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