JP2023529025A - 抗ウイルス処置としてのアゼラスチン - Google Patents

抗ウイルス処置としてのアゼラスチン Download PDF

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Publication number
JP2023529025A
JP2023529025A JP2023516644A JP2023516644A JP2023529025A JP 2023529025 A JP2023529025 A JP 2023529025A JP 2023516644 A JP2023516644 A JP 2023516644A JP 2023516644 A JP2023516644 A JP 2023516644A JP 2023529025 A JP2023529025 A JP 2023529025A
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JP
Japan
Prior art keywords
azelastine
virus
cov
sars
compound
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JP2023516644A
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English (en)
Japanese (ja)
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JP2023529025A5 (https=
Inventor
ナギ,エスター
ナギ,ガボール
シヤルト,バレリア
コンラット,ロベルト
Original Assignee
ツェビナ・ゲーエムベーハー
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Priority claimed from EP20184767.0A external-priority patent/EP3936132A1/en
Application filed by ツェビナ・ゲーエムベーハー filed Critical ツェビナ・ゲーエムベーハー
Publication of JP2023529025A publication Critical patent/JP2023529025A/ja
Publication of JP2023529025A5 publication Critical patent/JP2023529025A5/ja
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2023516644A 2020-05-29 2021-05-28 抗ウイルス処置としてのアゼラスチン Pending JP2023529025A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
EP20177451 2020-05-29
EP20177451.0 2020-05-29
EP20184767.0 2020-07-08
EP20184767.0A EP3936132A1 (en) 2020-07-08 2020-07-08 Azelastine as antiviral treatment
EP20195740 2020-09-11
EP20195740.4 2020-09-11
EP21171333 2021-04-29
EP21171333.4 2021-04-29
PCT/EP2021/064338 WO2021239943A1 (en) 2020-05-29 2021-05-28 Azelastine as antiviral treatment

Publications (2)

Publication Number Publication Date
JP2023529025A true JP2023529025A (ja) 2023-07-06
JP2023529025A5 JP2023529025A5 (https=) 2024-06-04

Family

ID=76059910

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023516644A Pending JP2023529025A (ja) 2020-05-29 2021-05-28 抗ウイルス処置としてのアゼラスチン

Country Status (21)

Country Link
US (3) US20230201216A1 (https=)
EP (2) EP3934653B1 (https=)
JP (1) JP2023529025A (https=)
KR (1) KR20230021009A (https=)
CN (1) CN116406273A (https=)
AU (1) AU2021279280A1 (https=)
BR (1) BR112022023897A2 (https=)
CA (1) CA3184167A1 (https=)
DK (1) DK3934653T3 (https=)
ES (1) ES2937145T3 (https=)
FI (1) FI3934653T3 (https=)
HU (1) HUE060929T2 (https=)
IL (1) IL298543A (https=)
JO (1) JOP20220319B1 (https=)
LT (1) LT3934653T (https=)
MX (1) MX2022015074A (https=)
PL (1) PL3934653T3 (https=)
RS (1) RS63940B1 (https=)
SI (1) SI3934653T1 (https=)
SM (1) SMT202300036T1 (https=)
WO (1) WO2021239943A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11806359B2 (en) 2020-03-31 2023-11-07 Phoenix Biotechnology, Inc. Method and compositions for treating Coronavirus infection
ES2937145T3 (es) * 2020-05-29 2023-03-24 CEBINA GmbH Azelastina como tratamiento antiviral

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01153639A (ja) * 1987-11-13 1989-06-15 Asta Pharma Ag 鼻又は目に使用する薬剤及びその製造法
JP2008285474A (ja) * 2007-04-17 2008-11-27 Daiichi Sankyo Healthcare Co Ltd 抗アデノウイルス剤を含有する医薬組成物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3836579A1 (de) * 1987-11-13 1989-05-24 Asta Pharma Ag Azelastin enthaltende arzneimittel zur anwendung in der nase und/oder am auge
US20100311656A1 (en) * 2003-04-23 2010-12-09 Sciclone Pharmaceuticals, Inc. Treatment or prevention of respiratory viral infections with alpha thymosin peptides
US8758816B2 (en) * 2004-11-24 2014-06-24 Meda Pharmaceuticals Inc. Compositions comprising azelastine and methods of use thereof
US8642069B2 (en) * 2008-08-27 2014-02-04 Alexander D. Goldin Composition and method for treating colds
WO2021207213A2 (en) * 2020-04-07 2021-10-14 University Of Florida Research Foundation, Incorporated Methods to prevent sars-cov-2 infection and treat covid-19
US20230142221A1 (en) * 2020-04-10 2023-05-11 Kamal Khan Mubarak Compositions and methods for modulating ace2 receptor
CN113521289A (zh) * 2020-04-16 2021-10-22 中国科学院上海药物研究所 15种药物有效成分在抗病毒感染中的应用
ES2937145T3 (es) * 2020-05-29 2023-03-24 CEBINA GmbH Azelastina como tratamiento antiviral

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01153639A (ja) * 1987-11-13 1989-06-15 Asta Pharma Ag 鼻又は目に使用する薬剤及びその製造法
JP2008285474A (ja) * 2007-04-17 2008-11-27 Daiichi Sankyo Healthcare Co Ltd 抗アデノウイルス剤を含有する医薬組成物

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ARXIV, QUANTITATIVE BIOLOGY, MOLECULAR NETWORKS, vol. arXiv:2004.07229, JPN6025028517, April 2020 (2020-04-01), ISSN: 0005639619 *
BIOINFORMATION, vol. 16, no. 3, JPN6025028518, March 2020 (2020-03-01), pages 236 - 244, ISSN: 0005639620 *

Also Published As

Publication number Publication date
AU2021279280A1 (en) 2023-01-05
EP3934653A1 (en) 2022-01-12
SMT202300036T1 (it) 2023-03-17
MX2022015074A (es) 2023-02-16
PL3934653T3 (pl) 2023-03-13
US11273163B2 (en) 2022-03-15
EP4190333A1 (en) 2023-06-07
RS63940B1 (sr) 2023-02-28
HUE060929T2 (hu) 2023-04-28
EP3934653B1 (en) 2022-11-09
FI3934653T3 (fi) 2023-03-01
IL298543A (en) 2023-01-01
BR112022023897A2 (pt) 2023-04-04
KR20230021009A (ko) 2023-02-13
ES2937145T3 (es) 2023-03-24
WO2021239943A1 (en) 2021-12-02
SI3934653T1 (sl) 2023-04-28
CN116406273A (zh) 2023-07-07
CA3184167A1 (en) 2021-12-02
JOP20220319B1 (ar) 2024-12-22
US11433080B2 (en) 2022-09-06
US20230201216A1 (en) 2023-06-29
US20210369730A1 (en) 2021-12-02
LT3934653T (lt) 2023-02-27
DK3934653T3 (da) 2023-02-13
US20220143040A1 (en) 2022-05-12

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