JP2023526536A - 呼吸器免疫病態の吸入型il-1遮断治療 - Google Patents

呼吸器免疫病態の吸入型il-1遮断治療 Download PDF

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Publication number
JP2023526536A
JP2023526536A JP2022571335A JP2022571335A JP2023526536A JP 2023526536 A JP2023526536 A JP 2023526536A JP 2022571335 A JP2022571335 A JP 2022571335A JP 2022571335 A JP2022571335 A JP 2022571335A JP 2023526536 A JP2023526536 A JP 2023526536A
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JP
Japan
Prior art keywords
nebulizer
rhil
anakinra
nebulized
interleukin
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JP2022571335A
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English (en)
Japanese (ja)
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JP2023526536A5 (enExample
Inventor
リング、スティーヴン、エー.
バラノウスキ、リン、エー.
クライザー、ケイトリン、アール.
パラシオス、ミッシェル
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Altavant Sciences GmbH
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Altavant Sciences GmbH
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Publication of JP2023526536A publication Critical patent/JP2023526536A/ja
Publication of JP2023526536A5 publication Critical patent/JP2023526536A5/ja
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1793Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/20Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2022571335A 2020-05-21 2021-05-20 呼吸器免疫病態の吸入型il-1遮断治療 Withdrawn JP2023526536A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063028494P 2020-05-21 2020-05-21
US63/028,494 2020-05-21
US202063072895P 2020-08-31 2020-08-31
US63/072,895 2020-08-31
PCT/IB2021/000347 WO2021234457A1 (en) 2020-05-21 2021-05-20 An inhaled il-1 blockade treatment for respiratory tract immunopathology

Publications (2)

Publication Number Publication Date
JP2023526536A true JP2023526536A (ja) 2023-06-21
JP2023526536A5 JP2023526536A5 (enExample) 2024-05-28

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ID=76807913

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JP2022571335A Withdrawn JP2023526536A (ja) 2020-05-21 2021-05-20 呼吸器免疫病態の吸入型il-1遮断治療

Country Status (9)

Country Link
US (1) US20230210768A1 (enExample)
EP (1) EP4153213A1 (enExample)
JP (1) JP2023526536A (enExample)
KR (1) KR20230015397A (enExample)
CN (1) CN116348144A (enExample)
AU (1) AU2021277585A1 (enExample)
CA (1) CA3178404A1 (enExample)
MX (1) MX2022014626A (enExample)
WO (1) WO2021234457A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2022006636A (es) * 2019-12-02 2022-11-09 Altavant Sciences Gmbh Tratamiento de trastornos de las vías respiratorias bajas.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1565620A (zh) * 2003-06-09 2005-01-19 上海复旦张江生物医药股份有限公司 白细胞介素-1受体拮抗剂治疗非典型性肺炎的用途
HUE048024T2 (hu) * 2006-08-10 2020-05-28 Roy C Levitt Anakinra bronchiolitis obliterans szindróma kezelésében való alkalmazásra
MX2022006636A (es) * 2019-12-02 2022-11-09 Altavant Sciences Gmbh Tratamiento de trastornos de las vías respiratorias bajas.

Also Published As

Publication number Publication date
AU2021277585A1 (en) 2022-12-15
WO2021234457A1 (en) 2021-11-25
US20230210768A1 (en) 2023-07-06
MX2022014626A (es) 2023-02-22
KR20230015397A (ko) 2023-01-31
CN116348144A (zh) 2023-06-27
CA3178404A1 (en) 2021-11-25
EP4153213A1 (en) 2023-03-29

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