JP2023526451A5 - - Google Patents

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Publication number
JP2023526451A5
JP2023526451A5 JP2022570573A JP2022570573A JP2023526451A5 JP 2023526451 A5 JP2023526451 A5 JP 2023526451A5 JP 2022570573 A JP2022570573 A JP 2022570573A JP 2022570573 A JP2022570573 A JP 2022570573A JP 2023526451 A5 JP2023526451 A5 JP 2023526451A5
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JP
Japan
Prior art keywords
pharmaceutical composition
composition according
approximately
pharmaceutically acceptable
administered
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022570573A
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English (en)
Japanese (ja)
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JP2023526451A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/GB2021/051220 external-priority patent/WO2021234391A1/en
Publication of JP2023526451A publication Critical patent/JP2023526451A/ja
Publication of JP2023526451A5 publication Critical patent/JP2023526451A5/ja
Pending legal-status Critical Current

Links

JP2022570573A 2020-05-20 2021-05-20 ネクチン-4に特異的な二環式ペプチドリガンド及びその使用 Pending JP2023526451A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063027536P 2020-05-20 2020-05-20
US63/027,536 2020-05-20
PCT/GB2021/051220 WO2021234391A1 (en) 2020-05-20 2021-05-20 Bicyclic peptide ligands specific for nectin-4 and uses thereof

Publications (2)

Publication Number Publication Date
JP2023526451A JP2023526451A (ja) 2023-06-21
JP2023526451A5 true JP2023526451A5 (https=) 2024-05-22

Family

ID=76532225

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022570573A Pending JP2023526451A (ja) 2020-05-20 2021-05-20 ネクチン-4に特異的な二環式ペプチドリガンド及びその使用

Country Status (10)

Country Link
US (1) US20230181749A1 (https=)
EP (1) EP4153240A1 (https=)
JP (1) JP2023526451A (https=)
KR (1) KR20230037502A (https=)
CN (1) CN115697417A (https=)
AU (1) AU2021276616A1 (https=)
CA (1) CA3179152A1 (https=)
IL (1) IL298382A (https=)
MX (1) MX2022014550A (https=)
WO (1) WO2021234391A1 (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107148425B (zh) 2014-10-29 2021-08-03 拜斯科阿迪有限公司 对mt1-mmp特异性的双环肽配体
EP3645549A1 (en) 2017-06-26 2020-05-06 BicycleRD Limited Bicyclic peptide ligands with detectable moieties and uses thereof
JP7670481B2 (ja) 2017-08-04 2025-04-30 バイスクルテクス・リミテッド Cd137に対して特異的な二環式ペプチドリガンド
CN111902429A (zh) 2018-02-23 2020-11-06 拜斯科技术开发有限公司 多聚体双环肽配体
IL279489B2 (en) 2018-06-22 2025-10-01 Bicycletx Ltd Bicyclic peptide ligands specific for nectin-4, a drug conjugate containing the peptide ligands and a pharmaceutical composition containing the drug conjugate
GB201820295D0 (en) 2018-12-13 2019-01-30 Bicyclerd Ltd Bicyclic peptide ligands specific for MT1-MMP
GB201820325D0 (en) 2018-12-13 2019-01-30 Bicyclerd Ltd Bicyclic peptide ligands specific for psma
GB201820288D0 (en) 2018-12-13 2019-01-30 Bicycle Tx Ltd Bicycle peptide ligaands specific for MT1-MMP
WO2020128527A1 (en) 2018-12-21 2020-06-25 Bicyclerd Limited Bicyclic peptide ligands specific for pd-l1
US12492224B2 (en) 2018-12-21 2025-12-09 Bicycletx Limited Bicyclic peptide ligands specific for PD-L1
GB201900529D0 (en) 2019-01-15 2019-03-06 Bicycletx Ltd Bicyclic peptide ligands specific for CD38
TWI860386B (zh) 2019-07-30 2024-11-01 英商拜西可泰克斯有限公司 異質雙環肽複合物
AU2021322934A1 (en) 2020-08-03 2023-03-30 Bicycletx Limited Peptide-based linkers
CN121511098A (zh) * 2023-06-01 2026-02-10 拜斯科技术开发有限公司 对nectin-4具有特异性的双环肽配体及其用途
WO2024248859A1 (en) * 2023-06-01 2024-12-05 Bicycletx Limited Bicyclic peptide ligands specific for nectin-4 and uses thereof
CN117003830A (zh) * 2023-08-04 2023-11-07 湖南中晟全肽生化有限公司 靶向Nectin-4的多肽及其用途
AU2024342769A1 (en) * 2023-09-13 2026-04-23 Bicycletx Limited Bicyclic peptide ligands specific for nectin-4 and uses thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ283516B6 (cs) * 1996-09-12 1998-04-15 Galena A.S. Léčivé přípravky, zejména pro vnitřní aplikaci, ve formě samomikroemulgujících terapeutických systémů
WO2010056796A1 (en) * 2008-11-12 2010-05-20 Theraclone Sciences, Inc. Human m2e peptide immunogens
JP6595458B2 (ja) * 2013-09-20 2019-10-23 ブリストル−マイヤーズ スクイブ カンパニー 腫瘍を処置するための抗lag−3抗体と抗pd−1抗体との組合せ
AU2015320545C1 (en) * 2014-09-24 2020-05-14 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and formulations thereof
IL324591A (en) * 2017-08-31 2026-01-01 Daiichi Sankyo Co Ltd Improved antibody-drug conjugate production methods
TWI825046B (zh) * 2017-12-19 2023-12-11 英商拜西可泰克斯有限公司 Epha2特用之雙環胜肽配位基
IL279489B2 (en) * 2018-06-22 2025-10-01 Bicycletx Ltd Bicyclic peptide ligands specific for nectin-4, a drug conjugate containing the peptide ligands and a pharmaceutical composition containing the drug conjugate
WO2020178574A1 (en) * 2019-03-04 2020-09-10 Bicyclerd Limited Synthesis of bicycle toxin conjugates, and intermediates thereof
JOP20210284A1 (ar) * 2019-04-24 2023-01-30 Janssen Pharmaceuticals Inc الإعطاء غير المتجانس للقاحات تاو
CN113527486B (zh) * 2020-04-21 2025-12-02 迈威(上海)生物科技股份有限公司 一种抗Nectin-4的抗体及其应用
EP4208259A2 (en) * 2020-09-04 2023-07-12 NovaRock Biotherapeutics, Ltd. Nectin-4 antibodies and uses thereof

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