JP2023505756A5 - - Google Patents
Info
- Publication number
- JP2023505756A5 JP2023505756A5 JP2022531404A JP2022531404A JP2023505756A5 JP 2023505756 A5 JP2023505756 A5 JP 2023505756A5 JP 2022531404 A JP2022531404 A JP 2022531404A JP 2022531404 A JP2022531404 A JP 2022531404A JP 2023505756 A5 JP2023505756 A5 JP 2023505756A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- pharmaceutically acceptable
- polysorbate
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962940966P | 2019-11-27 | 2019-11-27 | |
| US62/940,966 | 2019-11-27 | ||
| PCT/GB2020/053026 WO2021105694A1 (en) | 2019-11-27 | 2020-11-27 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EphA2 AND USES THEREOF |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023505756A JP2023505756A (ja) | 2023-02-13 |
| JP2023505756A5 true JP2023505756A5 (https=) | 2023-12-05 |
Family
ID=73854820
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022531404A Pending JP2023505756A (ja) | 2019-11-27 | 2020-11-27 | ＥｐｈＡ２に特異的な二環式ペプチドリガンドおよびその使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20230025916A1 (https=) |
| EP (1) | EP4065085A1 (https=) |
| JP (1) | JP2023505756A (https=) |
| KR (1) | KR20220131898A (https=) |
| CN (1) | CN114760988A (https=) |
| AU (1) | AU2020392890A1 (https=) |
| CA (1) | CA3158741A1 (https=) |
| IL (1) | IL293200A (https=) |
| MX (1) | MX2022006001A (https=) |
| WO (1) | WO2021105694A1 (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107148425B (zh) | 2014-10-29 | 2021-08-03 | 拜斯科阿迪有限公司 | 对mt1-mmp特异性的双环肽配体 |
| EP3645549A1 (en) | 2017-06-26 | 2020-05-06 | BicycleRD Limited | Bicyclic peptide ligands with detectable moieties and uses thereof |
| JP7670481B2 (ja) | 2017-08-04 | 2025-04-30 | バイスクルテクス・リミテッド | Ｃｄ１３７に対して特異的な二環式ペプチドリガンド |
| GB201721265D0 (en) | 2017-12-19 | 2018-01-31 | Bicyclerd Ltd | Bicyclic peptide ligands specific for EphA2 |
| TWI825046B (zh) | 2017-12-19 | 2023-12-11 | 英商拜西可泰克斯有限公司 | Epha2特用之雙環胜肽配位基 |
| CN111902429A (zh) | 2018-02-23 | 2020-11-06 | 拜斯科技术开发有限公司 | 多聚体双环肽配体 |
| EP3774851A1 (en) | 2018-04-04 | 2021-02-17 | BicycleTX Limited | Heterotandem bicyclic peptide complexes |
| GB201810316D0 (en) | 2018-06-22 | 2018-08-08 | Bicyclerd Ltd | Peptide ligands for binding to EphA2 |
| IL279489B2 (en) | 2018-06-22 | 2025-10-01 | Bicycletx Ltd | Bicyclic peptide ligands specific for nectin-4, a drug conjugate containing the peptide ligands and a pharmaceutical composition containing the drug conjugate |
| GB201820325D0 (en) | 2018-12-13 | 2019-01-30 | Bicyclerd Ltd | Bicyclic peptide ligands specific for psma |
| GB201820288D0 (en) | 2018-12-13 | 2019-01-30 | Bicycle Tx Ltd | Bicycle peptide ligaands specific for MT1-MMP |
| GB201820295D0 (en) | 2018-12-13 | 2019-01-30 | Bicyclerd Ltd | Bicyclic peptide ligands specific for MT1-MMP |
| US12492224B2 (en) | 2018-12-21 | 2025-12-09 | Bicycletx Limited | Bicyclic peptide ligands specific for PD-L1 |
| WO2020128527A1 (en) | 2018-12-21 | 2020-06-25 | Bicyclerd Limited | Bicyclic peptide ligands specific for pd-l1 |
| GB201900529D0 (en) | 2019-01-15 | 2019-03-06 | Bicycletx Ltd | Bicyclic peptide ligands specific for CD38 |
| WO2020225577A1 (en) | 2019-05-09 | 2020-11-12 | Bicycletx Limited | Bicyclic peptide ligands specific for ox40 |
| TWI860386B (zh) | 2019-07-30 | 2024-11-01 | 英商拜西可泰克斯有限公司 | 異質雙環肽複合物 |
| CN115698720A (zh) * | 2020-06-12 | 2023-02-03 | 拜斯科技术开发有限公司 | 特征在于促红细胞生成素产生肝细胞受体a2(epha2)的过表达的疾病的治疗 |
| AU2021322934A1 (en) | 2020-08-03 | 2023-03-30 | Bicycletx Limited | Peptide-based linkers |
| AU2022328932B2 (en) * | 2021-08-17 | 2026-02-19 | Tianjin Conjustar Biologics Co., Ltd. | Polypeptide drug conjugate having novel structure and application thereof |
| WO2024248860A1 (en) * | 2023-06-01 | 2024-12-05 | Bicycletx Limited | Bicyclic peptide ligands specific for epha2 and uses thereof |
| CN121889170A (zh) * | 2023-06-01 | 2026-04-17 | 拜斯科技术开发有限公司 | 对EphA2特异的双环肽配体及其用途 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2653545A1 (en) | 2008-02-05 | 2013-10-23 | Bicycle Therapeutics Limited | Methods and compositions |
| TWI825046B (zh) * | 2017-12-19 | 2023-12-11 | 英商拜西可泰克斯有限公司 | Epha2特用之雙環胜肽配位基 |
-
2020
- 2020-11-27 MX MX2022006001A patent/MX2022006001A/es unknown
- 2020-11-27 AU AU2020392890A patent/AU2020392890A1/en active Pending
- 2020-11-27 EP EP20825161.1A patent/EP4065085A1/en active Pending
- 2020-11-27 CA CA3158741A patent/CA3158741A1/en active Pending
- 2020-11-27 KR KR1020227021780A patent/KR20220131898A/ko active Pending
- 2020-11-27 JP JP2022531404A patent/JP2023505756A/ja active Pending
- 2020-11-27 IL IL293200A patent/IL293200A/en unknown
- 2020-11-27 US US17/779,226 patent/US20230025916A1/en not_active Abandoned
- 2020-11-27 CN CN202080082789.3A patent/CN114760988A/zh active Pending
- 2020-11-27 WO PCT/GB2020/053026 patent/WO2021105694A1/en not_active Ceased
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