JP2023524807A5 - - Google Patents
Info
- Publication number
- JP2023524807A5 JP2023524807A5 JP2022567509A JP2022567509A JP2023524807A5 JP 2023524807 A5 JP2023524807 A5 JP 2023524807A5 JP 2022567509 A JP2022567509 A JP 2022567509A JP 2022567509 A JP2022567509 A JP 2022567509A JP 2023524807 A5 JP2023524807 A5 JP 2023524807A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- seq
- acid sequence
- protein
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063020505P | 2020-05-05 | 2020-05-05 | |
| US63/020,505 | 2020-05-05 | ||
| US202163169755P | 2021-04-01 | 2021-04-01 | |
| US63/169,755 | 2021-04-01 | ||
| PCT/US2021/030900 WO2021226243A1 (en) | 2020-05-05 | 2021-05-05 | Protein s antibodies, methods of making and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023524807A JP2023524807A (ja) | 2023-06-13 |
| JP2023524807A5 true JP2023524807A5 (enExample) | 2024-05-22 |
Family
ID=76076555
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022567509A Pending JP2023524807A (ja) | 2020-05-05 | 2021-05-05 | プロテインｓ抗体、その作製方法および使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (4) | US12441810B2 (enExample) |
| EP (1) | EP4146705A1 (enExample) |
| JP (1) | JP2023524807A (enExample) |
| KR (1) | KR20230019097A (enExample) |
| CN (1) | CN115916835A (enExample) |
| AU (1) | AU2021268943A1 (enExample) |
| CA (1) | CA3177329A1 (enExample) |
| GB (1) | GB2610720A (enExample) |
| IL (1) | IL297947A (enExample) |
| TW (2) | TWI910161B (enExample) |
| WO (2) | WO2021226245A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12441810B2 (en) | 2020-05-05 | 2025-10-14 | Vega Therapeutics, Inc. | Protein S antibodies, methods of making and uses thereof |
| GB202402535D0 (en) * | 2024-02-22 | 2024-04-10 | Imperial College Innovations Ltd | Fusion proteins |
| WO2025240928A1 (en) * | 2024-05-16 | 2025-11-20 | Vega Therapeutics, Inc. | Treatment of von willebrand disease |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5187067A (en) | 1986-12-15 | 1993-02-16 | Teijin Limited | Immunological determination of free human protein S and C4bp-protein S complex |
| US5366861A (en) | 1987-08-12 | 1994-11-22 | Teijin Limited | Immunoassay and reagent kit used therefor |
| US5530101A (en) * | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5147638A (en) | 1988-12-30 | 1992-09-15 | Oklahoma Medical Research Foundation | Inhibition of tumor growth by blockade of the protein C system |
| US6423313B1 (en) | 1988-12-30 | 2002-07-23 | Oklahoma Medical Research Foundation | Inhibition of tumor growth by blockade of the protein C system |
| US5321123A (en) | 1991-07-02 | 1994-06-14 | The Scripps Research Institute | Protein S polypeptides and anti-peptide antibodies that inhibit protein S binding to C4B binding protein, diagnostic systems and therapeutic methods |
| ES2142317T3 (es) * | 1991-07-02 | 2000-04-16 | Scripps Research Inst | Polipeptidos de proteinas s y uso de los mismos. |
| DK0658168T3 (da) | 1992-08-27 | 2001-01-22 | Sanquin Bloedvoorziening | Antistoffer, som er specifikke for et hæmostatisk protein, anvendelse heraf til isolering af intakt protein, hæmostatiske p |
| US20030143759A1 (en) | 1995-10-20 | 2003-07-31 | Bjorn Dahlback | Assays for determining anticoagulant cofactor activity |
| SE9604378D0 (sv) * | 1996-11-27 | 1996-11-27 | Tac Ab | Methods and reagents for determining protein S |
| US6379975B1 (en) | 1996-11-27 | 2002-04-30 | T.A.C. Thrombosis And Coagulation Aktiebolag | Methods and reagents for determining protein S |
| US7053202B2 (en) * | 2001-10-19 | 2006-05-30 | Millennium Pharmaceuticals, Inc. | Immunoglobulin DNA cassette molecules, monobody constructs, methods of production, and methods of use therefor |
| US20030124118A1 (en) | 2001-11-27 | 2003-07-03 | Rasmus Rojkjaer | Pharmaceutical composition comprising factor VII polypeptides and protein S inhibitors |
| US20080057059A1 (en) | 2001-11-09 | 2008-03-06 | Novo Nordisk Healthcare A/G | Pharmaceutical Composition Comprising Factor VII Polypeptides and Protein S Inhibitors |
| US20030165485A1 (en) | 2001-11-09 | 2003-09-04 | Goran Bertilsson | Functional role and potential therapeutic use of Reelin, Gas6 and Protein S in relation to adult neural stem or progenitor cells |
| WO2007008966A1 (en) | 2005-07-12 | 2007-01-18 | The Scripps Research Institute | Elisa to detect multimeric forms of a protein |
| EP1920068A4 (en) | 2005-07-28 | 2008-08-13 | American Diagnostica Inc | LUPIC ANTICOAGULANT TEST |
| EP1919499A2 (en) | 2005-07-29 | 2008-05-14 | Universiteit van Maastricht | Regulation of tissue factor activity by protein s and tissue factor pathway inhibitor |
| EP2217716A4 (en) | 2007-11-09 | 2011-02-09 | Salk Inst For Biological Studi | USE OF TAM RECEPTOR INHIBITORS AS ANTIMICROBIAL AGENTS |
| EP2165710A1 (en) | 2008-09-19 | 2010-03-24 | Institut Curie | Tyrosine kinase receptor Tyro3 as a therapeutic target in the treatment of a bladder tumor |
| CN105705517A (zh) * | 2013-11-07 | 2016-06-22 | 诺和诺德股份有限公司 | 用于治疗凝血障碍的新方法和抗体 |
| CN106232615B (zh) * | 2014-02-28 | 2021-06-01 | 3B制药有限公司 | 肽及其使用方法 |
| US12441810B2 (en) | 2020-05-05 | 2025-10-14 | Vega Therapeutics, Inc. | Protein S antibodies, methods of making and uses thereof |
| CN115884986A (zh) | 2020-06-29 | 2023-03-31 | Inserm(法国国家健康医学研究院) | 抗蛋白s单域抗体和包含其的多肽 |
| WO2024124136A1 (en) | 2022-12-09 | 2024-06-13 | Vega Therapeutics, Inc. | Von willebrand disease animal models |
-
2021
- 2021-05-05 US US17/923,503 patent/US12441810B2/en active Active
- 2021-05-05 WO PCT/US2021/030902 patent/WO2021226245A1/en not_active Ceased
- 2021-05-05 JP JP2022567509A patent/JP2023524807A/ja active Pending
- 2021-05-05 WO PCT/US2021/030900 patent/WO2021226243A1/en not_active Ceased
- 2021-05-05 GB GB2217381.9A patent/GB2610720A/en not_active Withdrawn
- 2021-05-05 EP EP21728367.0A patent/EP4146705A1/en active Pending
- 2021-05-05 CN CN202180032466.8A patent/CN115916835A/zh active Pending
- 2021-05-05 KR KR1020227041141A patent/KR20230019097A/ko active Pending
- 2021-05-05 US US17/923,504 patent/US20230174672A1/en active Pending
- 2021-05-05 AU AU2021268943A patent/AU2021268943A1/en active Pending
- 2021-05-05 TW TW110116287A patent/TWI910161B/zh active
- 2021-05-05 IL IL297947A patent/IL297947A/en unknown
- 2021-05-05 CA CA3177329A patent/CA3177329A1/en active Pending
- 2021-05-05 TW TW110116289A patent/TW202208444A/zh unknown
-
2023
- 2023-11-10 US US18/506,872 patent/US12145999B2/en active Active
-
2024
- 2024-08-27 US US18/817,152 patent/US12421320B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2024026169A (ja) | 第ｘｉ因子抗体および使用方法 | |
| CA2705851C (en) | Anti-factor xi monoclonal antibodies and methods of use thereof | |
| TWI500427B (zh) | Ｉｌ－１結合蛋白 | |
| KR102702288B1 (ko) | 항-인자 XI/XIa 항체를 사용한 치료 방법 | |
| JP2026053563A (ja) | 補体関連疾患のための融合タンパク質構築物 | |
| TW201043241A (en) | IL-17 binding proteins | |
| TW201802121A (zh) | 抗因子XI/XIa抗體之逆轉結合劑及其用途 | |
| JP6162319B2 (ja) | ヒト化抗ｎ２抗体 | |
| US12145999B2 (en) | Protein S antibodies, methods of making and uses thereof | |
| TW202214701A (zh) | 抗ＦＸＩ／ＦＸＩａ抗體、其抗原結合片段及醫藥用途 | |
| AU2017265172B2 (en) | Anti-factor xi monoclonal antibodies and methods of use thereof | |
| AU2021202612A1 (en) | Inhibition of platelet aggregation using anti-human GPVI antibodies | |
| JP2025507448A (ja) | Ｖｗｆ標的化単特異性抗体により血液障害を処置する方法 | |
| US12319742B1 (en) | Antibodies that bind TNFRSF25 | |
| WO2024027771A1 (zh) | 靶向FAP和TGFβ的抗体融合蛋白及其用途 | |
| US12630631B2 (en) | Inhibition of platelet aggregation using anti- human gpvi antibodies | |
| US20250051452A1 (en) | Targeted regulation of platelet and megakaryocyte activation by heteroreceptor co-clustering | |
| RU2847356C2 (ru) | Антитела к фактору xi и способы их применения |