JP2023524401A5 - - Google Patents

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Publication number
JP2023524401A5
JP2023524401A5 JP2022563990A JP2022563990A JP2023524401A5 JP 2023524401 A5 JP2023524401 A5 JP 2023524401A5 JP 2022563990 A JP2022563990 A JP 2022563990A JP 2022563990 A JP2022563990 A JP 2022563990A JP 2023524401 A5 JP2023524401 A5 JP 2023524401A5
Authority
JP
Japan
Prior art keywords
capsid protein
aav
genetically modified
amino acid
mutated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022563990A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023524401A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/030489 external-priority patent/WO2021222899A1/en
Publication of JP2023524401A publication Critical patent/JP2023524401A/ja
Publication of JP2023524401A5 publication Critical patent/JP2023524401A5/ja
Priority to JP2025267976A priority Critical patent/JP2026062759A/ja
Pending legal-status Critical Current

Links

JP2022563990A 2020-05-01 2021-05-03 遺伝子治療の増強のためのアデノ随伴ウイルス（ａａｖ）の制御された修飾 Pending JP2023524401A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025267976A JP2026062759A (ja) 2020-05-01 2025-12-19 遺伝子治療の増強のためのアデノ随伴ウイルス（ａａｖ）の制御された修飾

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063018573P 2020-05-01 2020-05-01
US63/018,573 2020-05-01
PCT/US2021/030489 WO2021222899A1 (en) 2020-05-01 2021-05-03 Controlled modification of adeno-associated virus (aav) for enhanced gene therapy

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025267976A Division JP2026062759A (ja) 2020-05-01 2025-12-19 遺伝子治療の増強のためのアデノ随伴ウイルス（ａａｖ）の制御された修飾

Publications (2)

Publication Number Publication Date
JP2023524401A JP2023524401A (ja) 2023-06-12
JP2023524401A5 true JP2023524401A5 (https=) 2024-05-08

Family

ID=76392408

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022563990A Pending JP2023524401A (ja) 2020-05-01 2021-05-03 遺伝子治療の増強のためのアデノ随伴ウイルス（ａａｖ）の制御された修飾
JP2025267976A Pending JP2026062759A (ja) 2020-05-01 2025-12-19 遺伝子治療の増強のためのアデノ随伴ウイルス（ａａｖ）の制御された修飾

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025267976A Pending JP2026062759A (ja) 2020-05-01 2025-12-19 遺伝子治療の増強のためのアデノ随伴ウイルス（ａａｖ）の制御された修飾

Country Status (9)

Country Link
US (1) US20230175013A1 (https=)
EP (1) EP4143206A1 (https=)
JP (2) JP2023524401A (https=)
KR (1) KR20230005941A (https=)
CN (1) CN115551878A (https=)
AU (1) AU2021264081A1 (https=)
CA (1) CA3177573A1 (https=)
IL (1) IL297780A (https=)
WO (1) WO2021222899A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025188967A1 (en) 2024-03-06 2025-09-12 Trustees Of Boston College Precise adeno-associated virus-protein conjugates and uses thereof
WO2025230000A1 (ja) * 2024-05-01 2025-11-06 Ｊｃｒファーマ株式会社 修飾されたａａｖ粒子、その製造方法、関連する医薬及びその製造
WO2026037731A1 (en) 2024-08-12 2026-02-19 Coave Therapeutics Squaramide-modified viral vectors

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ302092B6 (cs) * 1998-02-12 2010-10-06 Immune Complex, Corporation Konjugát upraveného jaderného proteinu hepatitidy B, jeho cástice, inokulum a zpusob indukce protilátek
SI1633772T1 (sl) * 2003-06-19 2016-06-30 Genzyme Corporation AAV virioni z zmanjšano imunoreaktivnostjo in uporaba za ta namen
WO2010093784A2 (en) * 2009-02-11 2010-08-19 The University Of North Carolina At Chapel Hill Modified virus vectors and methods of making and using the same
CN104592364B (zh) * 2013-10-30 2018-05-01 北京大学 定点突变和定点修饰的腺相关病毒、其制备方法及应用
JP6836999B2 (ja) * 2015-03-24 2021-03-03 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニアＴｈｅ Ｒｅｇｅｎｔｓ Ｏｆ Ｔｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｃａｌｉｆｏｒｎｉａ アデノ随伴ウイルス変異体及びその使用方法
EP3813845A4 (en) * 2018-05-15 2022-10-26 President And Fellows Of Harvard College Viral vectors exhibiting improved gene delivery properties

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