JP2023522985A5 - - Google Patents
Info
- Publication number
- JP2023522985A5 JP2023522985A5 JP2022564243A JP2022564243A JP2023522985A5 JP 2023522985 A5 JP2023522985 A5 JP 2023522985A5 JP 2022564243 A JP2022564243 A JP 2022564243A JP 2022564243 A JP2022564243 A JP 2022564243A JP 2023522985 A5 JP2023522985 A5 JP 2023522985A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- seq
- manipulated
- vector
- expression
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063014344P | 2020-04-23 | 2020-04-23 | |
| US63/014,344 | 2020-04-23 | ||
| PCT/US2021/028808 WO2021216978A1 (en) | 2020-04-23 | 2021-04-23 | Cellular ablation of hla-class i mhc |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023522985A JP2023522985A (ja) | 2023-06-01 |
| JP2023522985A5 true JP2023522985A5 (https=) | 2024-05-01 |
| JP7821119B2 JP7821119B2 (ja) | 2026-02-26 |
Family
ID=75888299
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022564243A Active JP7821119B2 (ja) | 2020-04-23 | 2021-04-23 | Hlaクラスi mhcの細胞切除 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20230212585A1 (https=) |
| EP (1) | EP4139458A1 (https=) |
| JP (1) | JP7821119B2 (https=) |
| CN (1) | CN116134144A (https=) |
| IL (1) | IL297489A (https=) |
| WO (1) | WO2021216978A1 (https=) |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4166452A (en) | 1976-05-03 | 1979-09-04 | Generales Constantine D J Jr | Apparatus for testing human responses to stimuli |
| US4256108A (en) | 1977-04-07 | 1981-03-17 | Alza Corporation | Microporous-semipermeable laminated osmotic system |
| US4265874A (en) | 1980-04-25 | 1981-05-05 | Alza Corporation | Method of delivering drug with aid of effervescent activity generated in environment of use |
| WO2005108572A1 (de) * | 2004-05-06 | 2005-11-17 | Medizinische Hochschule Hannover | Verbindungen und verfahren zur immunsuppression |
| US8236771B2 (en) | 2004-05-18 | 2012-08-07 | National Institute Of Transplantation Foundation | Vectors and methods for long-term immune evasion to prolong transplant viability |
| JP6681837B2 (ja) * | 2014-03-11 | 2020-04-15 | セレクティスCellectis | 同種移植に適合するt細胞を作製するための方法 |
| US9997807B2 (en) | 2014-12-24 | 2018-06-12 | East Penn Manufacturing Co. | Vibration resistant valve assembly for lead acid batteries |
| JP2019532640A (ja) * | 2016-09-29 | 2019-11-14 | ナントクエスト インコーポレイテッド | 免疫原性が低下したhlaクラスi欠損nk−92細胞 |
| EP4029943A1 (en) * | 2017-05-08 | 2022-07-20 | Precision Biosciences, Inc. | Nucleic acid molecules encoding an engineered antigen receptor and an inhibitory nucleic acid molecule and methods of use thereof |
| EP3441461A1 (en) * | 2017-08-11 | 2019-02-13 | Baylor College of Medicine | Cd1d-restricted nkt cells as a platform for off-the-shelf cancer immunotherapy |
| EP3773629A4 (en) | 2018-03-27 | 2022-01-19 | AZTherapies, Inc. | CAR-TREG-BASED THERAPIES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES |
| KR102691932B1 (ko) * | 2019-04-03 | 2024-08-06 | 프리시젼 바이오사이언시스 인코포레이티드 | 마이크로RNA-적응 shRNA(shRNAmiR)를 포함하는 유전자-변형 면역 세포 |
-
2021
- 2021-04-23 CN CN202180044568.1A patent/CN116134144A/zh active Pending
- 2021-04-23 IL IL297489A patent/IL297489A/en unknown
- 2021-04-23 JP JP2022564243A patent/JP7821119B2/ja active Active
- 2021-04-23 US US17/919,736 patent/US20230212585A1/en active Pending
- 2021-04-23 EP EP21724978.8A patent/EP4139458A1/en active Pending
- 2021-04-23 WO PCT/US2021/028808 patent/WO2021216978A1/en not_active Ceased
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US12215313B2 (en) | Method of detecting new immunogenic T cell epitopes and isolating new antigen-specific T cell receptors by means of an MHC cell library | |
| JP7676472B2 (ja) | 細胞療法に使用するための、免疫学的に識別できる細胞表面変異体 | |
| JP6502544B2 (ja) | Hla g改変された細胞および方法 | |
| JP2022058995A (ja) | 操作されたTreg細胞 | |
| Welten et al. | Tcf1+ cells are required to maintain the inflationary T cell pool upon MCMV infection | |
| JP2020500552A (ja) | 新生抗原のウイルスによる送達方法 | |
| EP3898665B1 (en) | Cd22-specific t cell receptors and adoptive t cell therapy for treatment of b cell malignancies | |
| JP7471821B2 (ja) | Xla遺伝子療法用の最適化されたレンチウイルスベクター | |
| CN108603172A (zh) | 治疗性t细胞 | |
| JP2023522985A5 (https=) | ||
| JP2025093949A (ja) | SIRPαがサイレンシングされたナチュラルキラー(NK)細胞 | |
| KR20230096977A (ko) | Bob1에 대해 지시된 t 세포 수용체 및 이의 용도 | |
| JP2025069165A (ja) | 耐性を誘導するための操作された細胞 | |
| CN111107856A (zh) | 增强基于t细胞的免疫疗法的效力的组合物和方法 | |
| EP4735471A2 (en) | T-cell receptors | |
| CN117659164A (zh) | 识别ebv抗原的t细胞受体及其应用 | |
| CN102234659B (zh) | 沉默细胞因子信号抑制因子1并表达高迁移率族蛋白b1以及肿瘤相关抗原的质粒及其制备方法 | |
| CN119923271A (zh) | 包含结核病抗原的疫苗构建体 | |
| CN120019146A (zh) | 通用t细胞和组合物及它们的使用方法 | |
| CN117279651A (zh) | 通过修饰的Fc受体的移植细胞保护 | |
| JP2006501829A (ja) | Hoxで誘導される増殖を制限する遺伝子をブロックする幹細胞増殖因子およびその方法 | |
| KR20230066419A (ko) | 장기 이식 환자의 면역-요법을 위한 면역억제제 약물 저항성 무장 tcr t 세포 | |
| HK40014655A (en) | Immunologically discernible cell surface variants for use in cell therapy | |
| HK40014655B (en) | Immunologically discernible cell surface variants for use in cell therapy | |
| MacDonald | Understanding & optimizing human T regulatory cell function in patients with autoimmunity and/or undergoing transplantation |