JP2023522259A5 - - Google Patents
Info
- Publication number
- JP2023522259A5 JP2023522259A5 JP2022564039A JP2022564039A JP2023522259A5 JP 2023522259 A5 JP2023522259 A5 JP 2023522259A5 JP 2022564039 A JP2022564039 A JP 2022564039A JP 2022564039 A JP2022564039 A JP 2022564039A JP 2023522259 A5 JP2023522259 A5 JP 2023522259A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- group
- her2
- alkylene
- positive
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20382320 | 2020-04-21 | ||
| EP20382320.8 | 2020-04-21 | ||
| PCT/EP2021/060352 WO2021214126A1 (en) | 2020-04-21 | 2021-04-21 | Drug antibody conjugates |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023522259A JP2023522259A (ja) | 2023-05-29 |
| JP2023522259A5 true JP2023522259A5 (https=) | 2024-05-02 |
| JP7795475B2 JP7795475B2 (ja) | 2026-01-07 |
Family
ID=70391053
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022564039A Active JP7795475B2 (ja) | 2020-04-21 | 2021-04-21 | 薬物抗体コンジュゲート |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US20240131180A1 (https=) |
| EP (1) | EP4138923A1 (https=) |
| JP (1) | JP7795475B2 (https=) |
| KR (1) | KR20230004714A (https=) |
| CN (1) | CN115427081B (https=) |
| AR (1) | AR121894A1 (https=) |
| AU (1) | AU2021260792C1 (https=) |
| BR (1) | BR112022020823A2 (https=) |
| CA (1) | CA3175426A1 (https=) |
| CL (1) | CL2022002917A1 (https=) |
| CO (1) | CO2022016548A2 (https=) |
| CR (1) | CR20220581A (https=) |
| DO (1) | DOP2022000224A (https=) |
| EC (1) | ECSP22088584A (https=) |
| IL (1) | IL297028A (https=) |
| JO (1) | JOP20220265A1 (https=) |
| MX (1) | MX2022013298A (https=) |
| PE (1) | PE20230785A1 (https=) |
| PH (1) | PH12022552706A1 (https=) |
| TW (1) | TWI905170B (https=) |
| WO (1) | WO2021214126A1 (https=) |
| ZA (1) | ZA202211123B (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI824043B (zh) * | 2018-10-25 | 2023-12-01 | 西班牙商瑪製藥股份有限公司 | 藥物抗體共軛物 |
| WO2024186263A1 (en) | 2023-03-07 | 2024-09-12 | Axcynsis Therapeutics Pte. Ltd. | Antibody-drug conjugates comprising trabectedin and lurbinectedin derivatives |
| WO2025055920A1 (zh) * | 2023-09-11 | 2025-03-20 | 泰诚思(上海)生物医药有限公司 | 新型海鞘素衍生物、其制备方法及用途、抗体药物偶联物及其应用 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US5149804A (en) * | 1990-11-30 | 1992-09-22 | The Board Of Trustees Of The University Of Illinois | Ecteinascidins 736 and 722 |
| US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| ATE158021T1 (de) | 1990-08-29 | 1997-09-15 | Genpharm Int | Produktion und nützung nicht-menschliche transgentiere zur produktion heterologe antikörper |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| CA2140280A1 (en) | 1992-08-17 | 1994-03-03 | Avi J. Ashkenazi | Bispecific immunoadhesins |
| JP4046354B2 (ja) | 1996-03-18 | 2008-02-13 | ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム | 増大した半減期を有する免疫グロブリン様ドメイン |
| GB0119243D0 (en) | 2001-08-07 | 2001-10-03 | Pharma Mar Sa | Antitumoral analogs of ET-743 |
| GB0202544D0 (en) * | 2002-02-04 | 2002-03-20 | Pharma Mar Sa | The synthesis of naturally occuring ecteinascidins and related compounds |
| DK1545613T3 (da) | 2002-07-31 | 2011-11-14 | Seattle Genetics Inc | Auristatinkonjugater og deres anvendelse til behandling af cancer, en autoimmun sygdom eller en infektiøs sygdom |
| JP4993645B2 (ja) | 2004-12-01 | 2012-08-08 | ジェネンテック， インコーポレイテッド | 抗体薬剤結合体および方法 |
| CA3000520C (en) | 2005-08-24 | 2023-04-04 | Immunogen, Inc. | Process for preparing antibody maytansinoid conjugates |
| GB201309807D0 (en) * | 2013-05-31 | 2013-07-17 | Pharma Mar Sau | Antibody drug conjugates |
| KR102491180B1 (ko) | 2017-04-27 | 2023-01-20 | 파르마 마르 에스.에이. | 항종양 화합물 |
-
2021
- 2021-04-21 CN CN202180029877.1A patent/CN115427081B/zh active Active
- 2021-04-21 CA CA3175426A patent/CA3175426A1/en active Pending
- 2021-04-21 CR CR20220581A patent/CR20220581A/es unknown
- 2021-04-21 MX MX2022013298A patent/MX2022013298A/es unknown
- 2021-04-21 IL IL297028A patent/IL297028A/en unknown
- 2021-04-21 WO PCT/EP2021/060352 patent/WO2021214126A1/en not_active Ceased
- 2021-04-21 JP JP2022564039A patent/JP7795475B2/ja active Active
- 2021-04-21 PE PE2022002459A patent/PE20230785A1/es unknown
- 2021-04-21 TW TW110114348A patent/TWI905170B/zh active
- 2021-04-21 KR KR1020227040525A patent/KR20230004714A/ko active Pending
- 2021-04-21 AR ARP210101061A patent/AR121894A1/es unknown
- 2021-04-21 PH PH1/2022/552706A patent/PH12022552706A1/en unknown
- 2021-04-21 EP EP21719647.6A patent/EP4138923A1/en active Pending
- 2021-04-21 AU AU2021260792A patent/AU2021260792C1/en active Active
- 2021-04-21 BR BR112022020823A patent/BR112022020823A2/pt unknown
- 2021-04-21 US US17/920,000 patent/US20240131180A1/en active Pending
-
2022
- 2022-10-11 ZA ZA2022/11123A patent/ZA202211123B/en unknown
- 2022-10-19 JO JOJO/P/2022/0265A patent/JOP20220265A1/ar unknown
- 2022-10-19 DO DO2022000224A patent/DOP2022000224A/es unknown
- 2022-10-21 CL CL2022002917A patent/CL2022002917A1/es unknown
- 2022-11-17 EC ECSENADI202288584A patent/ECSP22088584A/es unknown
- 2022-11-17 CO CONC2022/0016548A patent/CO2022016548A2/es unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2022512830A5 (https=) | ||
| HRP20230275T1 (hr) | Antitijelo-lijek konjugati koji sadrže derivate ekteinascidina | |
| EP4349372A1 (en) | Antibody drug conjugate, and preparation method therefor and use thereof | |
| JP7811398B2 (ja) | 架橋ピロロベンゾジアゼピン二量体（ｐｂｄ）誘導体及びその共役体 | |
| JP2023522259A5 (https=) | ||
| CN113683622B (zh) | 生物活性物偶联物及其制备方法和用途 | |
| RU2684468C2 (ru) | Новые конъюгаты антител и их применения | |
| CN107921144B (zh) | 澳瑞他汀类似物及其与细胞结合分子的共轭偶联物 | |
| CA2928794C (en) | Anti-her2 antibody-drug conjugate | |
| AU2020200566B2 (en) | Novel Hydrophilic Linkers and Ligand-Drug Conjugates Thereof | |
| AU2012338436B2 (en) | Cytotoxic peptides and antibody drug conjugates thereof | |
| BR112020020466A2 (pt) | Conjugados de peptídeo de camptotecina | |
| EP3130608A1 (en) | (anti-her2 antibody)-drug conjugate | |
| RU2015156499A (ru) | Конъюгаты антитела с лекарственным средством | |
| AU2021251875A1 (en) | Charge variant linkers | |
| EP3662933A1 (en) | Cd48 antibodies and conjugates thereof | |
| CN116999572A (zh) | 抗体－药物偶联物、药物组合物及其在制备治疗肿瘤的药物中的应用 | |
| JP2023535598A5 (https=) | ||
| JP2023515845A (ja) | 抗－ｃｄ５６抗体－薬物複合体およびその治療での使用 | |
| JP2012522513A5 (https=) | ||
| CN111712520A (zh) | 磷脂酰肌醇聚糖3抗体及其偶联物 | |
| CA3204418A1 (en) | Linker-payloads and conjugates thereof | |
| JP2019507126A5 (https=) | ||
| KR20250137203A (ko) | 항체 약물 접합체 | |
| JP2022548530A5 (https=) |