JP2022548530A5 - - Google Patents
Info
- Publication number
- JP2022548530A5 JP2022548530A5 JP2022514767A JP2022514767A JP2022548530A5 JP 2022548530 A5 JP2022548530 A5 JP 2022548530A5 JP 2022514767 A JP2022514767 A JP 2022514767A JP 2022514767 A JP2022514767 A JP 2022514767A JP 2022548530 A5 JP2022548530 A5 JP 2022548530A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- substituted
- alkylene
- groups
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP19382765.6 | 2019-09-05 | ||
| EP19382765 | 2019-09-05 | ||
| PCT/EP2020/074695 WO2021043951A1 (en) | 2019-09-05 | 2020-09-04 | Drug antibody conjugates |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022548530A JP2022548530A (ja) | 2022-11-21 |
| JP2022548530A5 true JP2022548530A5 (https=) | 2023-09-11 |
Family
ID=67902467
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022514767A Pending JP2022548530A (ja) | 2019-09-05 | 2020-09-04 | 薬物抗体コンジュゲート |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20230218774A1 (https=) |
| EP (1) | EP4025253B1 (https=) |
| JP (1) | JP2022548530A (https=) |
| CN (1) | CN114615999B (https=) |
| TW (1) | TW202122116A (https=) |
| WO (1) | WO2021043951A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN119490650A (zh) * | 2023-08-17 | 2025-02-21 | 上海交通大学 | 自由基光偶联方法、用于实现光偶联的试剂盒与应用 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| ATE158021T1 (de) | 1990-08-29 | 1997-09-15 | Genpharm Int | Produktion und nützung nicht-menschliche transgentiere zur produktion heterologe antikörper |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| CA2140280A1 (en) | 1992-08-17 | 1994-03-03 | Avi J. Ashkenazi | Bispecific immunoadhesins |
| JP4046354B2 (ja) | 1996-03-18 | 2008-02-13 | ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム | 増大した半減期を有する免疫グロブリン様ドメイン |
| DK1545613T3 (da) | 2002-07-31 | 2011-11-14 | Seattle Genetics Inc | Auristatinkonjugater og deres anvendelse til behandling af cancer, en autoimmun sygdom eller en infektiøs sygdom |
| JP4993645B2 (ja) | 2004-12-01 | 2012-08-08 | ジェネンテック, インコーポレイテッド | 抗体薬剤結合体および方法 |
| CA3000520C (en) | 2005-08-24 | 2023-04-04 | Immunogen, Inc. | Process for preparing antibody maytansinoid conjugates |
| US9364555B2 (en) * | 2011-07-22 | 2016-06-14 | University of Pittsburgh—of the Commonwealth System of Higher Education | Pederin and psymberin agents |
| KR102547649B1 (ko) * | 2017-03-17 | 2023-06-23 | 파르마 마르, 에스.에이. | 항암 화합물 |
-
2020
- 2020-09-04 WO PCT/EP2020/074695 patent/WO2021043951A1/en not_active Ceased
- 2020-09-04 TW TW109130445A patent/TW202122116A/zh unknown
- 2020-09-04 CN CN202080062337.9A patent/CN114615999B/zh not_active Expired - Fee Related
- 2020-09-04 JP JP2022514767A patent/JP2022548530A/ja active Pending
- 2020-09-04 EP EP20764406.3A patent/EP4025253B1/en active Active
- 2020-09-04 US US17/640,689 patent/US20230218774A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2022512830A5 (https=) | ||
| HRP20230275T1 (hr) | Antitijelo-lijek konjugati koji sadrže derivate ekteinascidina | |
| JP7703727B2 (ja) | 抗her2抗体-薬物コンジュゲート | |
| AU2019349207B2 (en) | Ligand-drug conjugate of exatecan analogue, preparation method therefor and application thereof | |
| CA3125713C (en) | Antibody-pyrrolobenzodiazepine derivative conjugate | |
| JP2024508081A (ja) | 生物活性物質コンジュゲート、その調製方法及びその使用 | |
| JP2025169338A (ja) | 抗体-薬物コンジュゲートの改良製造方法 | |
| JP2023522259A5 (https=) | ||
| CN115515642A (zh) | 抗cd56抗体-药物偶联物及其在治疗中的用途 | |
| AU2021282669A1 (en) | Antibody-drug conjugates containing an anti-mesothelin antibody and uses thereof | |
| RU2015156499A (ru) | Конъюгаты антитела с лекарственным средством | |
| EP4556026A1 (en) | Antibody-drug conjugate, and preparation method therefor and use thereof | |
| JP7827624B2 (ja) | 抗cea抗体-エキサテカン類似体複合体及びその医薬用途 | |
| JP2023519776A5 (https=) | ||
| JP2019507126A5 (https=) | ||
| JP2022548530A5 (https=) | ||
| AU2024324172A1 (en) | Compound and antibody-drug conjugate comprising same | |
| JP2026508115A (ja) | リンカー薬物、その抗体-薬物コンジュゲート、並びにそれらの調製方法及び使用 | |
| CN120225226A (zh) | B7-h3抗体药物偶联物及其应用 | |
| AU2022350725A1 (en) | Antibody-drug conjugate, preparation method therefor, and pharmaceutical use thereof | |
| WO2025226868A1 (en) | Antibody drug conjugates and uses thereof | |
| WO2025218776A1 (zh) | 抗ror1抗体、其免疫缀合物及其应用 | |
| HK40086489A (en) | Anti-her2 antibody-drug conjugate | |
| HK40086489B (en) | Anti-her2 antibody-drug conjugate | |
| HK40112172A (en) | Anti-her2 antibody-drug conjugate |