JP2023520409A5 - - Google Patents

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Publication number
JP2023520409A5
JP2023520409A5 JP2022559600A JP2022559600A JP2023520409A5 JP 2023520409 A5 JP2023520409 A5 JP 2023520409A5 JP 2022559600 A JP2022559600 A JP 2022559600A JP 2022559600 A JP2022559600 A JP 2022559600A JP 2023520409 A5 JP2023520409 A5 JP 2023520409A5
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JP
Japan
Prior art keywords
scfv
sequence
seq
cell
domain
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2022559600A
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English (en)
Japanese (ja)
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JP2023520409A (ja
JP7840865B2 (ja
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Priority claimed from PCT/US2021/025255 external-priority patent/WO2021202799A2/en
Publication of JP2023520409A publication Critical patent/JP2023520409A/ja
Publication of JP2023520409A5 publication Critical patent/JP2023520409A5/ja
Priority to JP2026050913A priority Critical patent/JP2026108769A/ja
Application granted granted Critical
Publication of JP7840865B2 publication Critical patent/JP7840865B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2022559600A 2020-03-31 2021-03-31 キメラ抗原受容体ターゲティングcd33 Active JP7840865B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2026050913A JP2026108769A (ja) 2020-03-31 2026-03-25 キメラ抗原受容体ターゲティングcd33

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063003196P 2020-03-31 2020-03-31
US63/003,196 2020-03-31
PCT/US2021/025255 WO2021202799A2 (en) 2020-03-31 2021-03-31 Chimeric antigen receptors targeting cd33

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2026050913A Division JP2026108769A (ja) 2020-03-31 2026-03-25 キメラ抗原受容体ターゲティングcd33

Publications (3)

Publication Number Publication Date
JP2023520409A JP2023520409A (ja) 2023-05-17
JP2023520409A5 true JP2023520409A5 (enExample) 2024-03-29
JP7840865B2 JP7840865B2 (ja) 2026-04-06

Family

ID=77929997

Family Applications (2)

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JP2022559600A Active JP7840865B2 (ja) 2020-03-31 2021-03-31 キメラ抗原受容体ターゲティングcd33
JP2026050913A Pending JP2026108769A (ja) 2020-03-31 2026-03-25 キメラ抗原受容体ターゲティングcd33

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2026050913A Pending JP2026108769A (ja) 2020-03-31 2026-03-25 キメラ抗原受容体ターゲティングcd33

Country Status (6)

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US (2) US12570758B2 (enExample)
EP (1) EP4126959A4 (enExample)
JP (2) JP7840865B2 (enExample)
CN (1) CN115348973A (enExample)
CA (1) CA3172691A1 (enExample)
WO (1) WO2021202799A2 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2022386336A1 (en) * 2021-11-10 2024-05-16 The Trustees Of The University Of Pennsylvania Engineered chimeric antigen receptor (car) microglia-like cells for the treatment of neurodegenerative disorders

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008045962A2 (en) * 2006-10-10 2008-04-17 Mayo Foundation For Medical Education And Research Methods and materials related to anti-a (beta) antibodies
EP2814846B1 (en) 2012-02-13 2020-01-08 Seattle Children's Hospital d/b/a Seattle Children's Research Institute Bispecific chimeric antigen receptors and therapeutic uses thereof
AR097648A1 (es) 2013-09-13 2016-04-06 Amgen Inc Combinación de factores epigenéticos y compuestos biespecíficos que tienen como diana cd33 y cd3 en el tratamiento de leucemia mieloide
ES2765710T3 (es) * 2014-04-03 2020-06-10 Cellectis Receptores de antígeno quimérico específicos de CD33 para la inmunoterapia del cáncer
JP6831777B2 (ja) * 2014-07-21 2021-02-17 ノバルティス アーゲー Cd33キメラ抗原受容体を使用する癌の処置
GB201514875D0 (en) 2015-08-20 2015-10-07 Autolus Ltd Receptor
GB201518136D0 (en) 2015-10-14 2015-11-25 Glaxosmithkline Ip Dev Ltd Novel chimeric antigen receptors
JP7189019B2 (ja) 2016-02-05 2022-12-13 シティ・オブ・ホープ 中枢神経系の癌の治療のための操作されたt細胞の投与
CN118652336A (zh) * 2016-06-08 2024-09-17 普瑞赛格恩公司 Cd33特异性嵌合抗原受体
US20190233534A1 (en) 2016-07-14 2019-08-01 Fred Hutchinson Cancer Research Center Multiple bi-specific binding domain constructs with different epitope binding to treat cancer
KR102709603B1 (ko) * 2017-02-28 2024-09-27 보르 바이오파마 인크. 계통 특이적 단백질의 억제를 위한 조성물 및 방법
AU2018240556B2 (en) 2017-03-24 2025-02-27 Lentigen Technology, Inc. Compositions and methods for treating cancer with anti-CD33 immunotherapy
GB201707779D0 (en) 2017-05-15 2017-06-28 Autolus Ltd Cell
WO2018218207A1 (en) 2017-05-26 2018-11-29 Fred Hutchinson Cancer Research Center Anti-cd33 antibodies and uses thereof
WO2019084234A1 (en) 2017-10-26 2019-05-02 St. Jude Childen's Research Hospital, Inc. METHODS AND COMPOSITIONS FOR TREATING CD33 + CANCERS AND IMPROVING IN VIVO PERSISTENCE OF CHIMERIC ANTIGEN RECEPTOR T CELLS
US20210017277A1 (en) 2018-03-14 2021-01-21 The United States Of America,As Represented By The Secretary,Department Of Health And Human Services Anti-cd33 chimeric antigen receptors and their uses
JOP20190116A1 (ar) 2018-05-24 2019-11-24 Janssen Biotech Inc الأجسام المضادة لتكتل التمايز 33 (cd33)، والأجسام المضادة ثنائية النوعية لتكتل التمايز 33 (cd33)/تكتل التمايز 3 (cd3) واستخداماتها
WO2019246593A2 (en) 2018-06-22 2019-12-26 Fred Hutchinson Cancer Research Center Compositions and methods to target cll-1 and cd123 for the treatment of acute myeloid leukemia and related disorders
EP4126248A4 (en) * 2020-03-31 2024-07-10 Fred Hutchinson Cancer Center HUMAN ANTI-CD33 ANTIBODIES AND THEIR USES
EP4126925A4 (en) 2020-03-31 2024-07-24 Fred Hutchinson Cancer Center CHIMERIC ANTIGEN RECEPTORS TARGETED AGAINST CD33

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