JP2023518422A5 - - Google Patents
Info
- Publication number
- JP2023518422A5 JP2023518422A5 JP2022556046A JP2022556046A JP2023518422A5 JP 2023518422 A5 JP2023518422 A5 JP 2023518422A5 JP 2022556046 A JP2022556046 A JP 2022556046A JP 2022556046 A JP2022556046 A JP 2022556046A JP 2023518422 A5 JP2023518422 A5 JP 2023518422A5
- Authority
- JP
- Japan
- Prior art keywords
- nitrogen
- sulfur
- oxygen
- independently selected
- heteroatoms independently
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062990555P | 2020-03-17 | 2020-03-17 | |
| US62/990,555 | 2020-03-17 | ||
| US202063088945P | 2020-10-07 | 2020-10-07 | |
| US63/088,945 | 2020-10-07 | ||
| US202063123335P | 2020-12-09 | 2020-12-09 | |
| US63/123,335 | 2020-12-09 | ||
| US202163159102P | 2021-03-10 | 2021-03-10 | |
| US63/159,102 | 2021-03-10 | ||
| PCT/US2021/022794 WO2021188696A1 (en) | 2020-03-17 | 2021-03-17 | Stat degraders and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023518422A JP2023518422A (ja) | 2023-05-01 |
| JP2023518422A5 true JP2023518422A5 (https=) | 2024-03-29 |
Family
ID=77771311
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022556046A Pending JP2023518422A (ja) | 2020-03-17 | 2021-03-17 | Ｓｔａｔ分解剤およびそれらの使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20240016942A1 (https=) |
| EP (1) | EP4121055A4 (https=) |
| JP (1) | JP2023518422A (https=) |
| CN (1) | CN115776891A (https=) |
| AU (1) | AU2021238333A1 (https=) |
| CA (1) | CA3170503A1 (https=) |
| IL (1) | IL296334A (https=) |
| MX (1) | MX2022011437A (https=) |
| WO (1) | WO2021188696A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12570679B2 (en) | 2019-03-29 | 2026-03-10 | Regents Of The University Of Michigan | STAT3 protein degraders |
| CN120574283A (zh) | 2019-04-05 | 2025-09-02 | 凯麦拉医疗公司 | Stat降解剂和其用途 |
| CN115677831B (zh) * | 2021-07-22 | 2026-03-17 | 杭州和正医药有限公司 | 拟肽类stat降解药物、组合物及应用 |
| CA3239730A1 (en) * | 2021-12-11 | 2023-06-15 | Christopher De Savi | Stat3 degraders and uses thereof |
| CA3253876A1 (en) * | 2022-03-31 | 2023-10-05 | Recludix Pharma, Inc. | STAT MODULATORS AND THEIR USES |
| WO2024030628A1 (en) * | 2022-08-05 | 2024-02-08 | Kymera Therapeutics, Inc. | Deuterated stat3 degraders and uses thereof |
| WO2024173291A1 (en) * | 2023-02-13 | 2024-08-22 | Regents Of The University Of Michigan | Compounds and compositions as stat3 degraders and uses thereof |
| WO2024173298A1 (en) * | 2023-02-13 | 2024-08-22 | Regents Of The University Of Michigan | Compounds and compositions as stat3 degraders and uses thereof |
| EP4709370A2 (en) * | 2023-05-09 | 2026-03-18 | Recludix Pharma, Inc. | Stat degraders and uses thereof |
| WO2024238603A2 (en) * | 2023-05-15 | 2024-11-21 | Recludix Pharma, Inc. | Stat degraders and uses thereof |
| EP4731622A1 (en) * | 2023-06-20 | 2026-04-29 | Regents of the University of Michigan | Compounds and compositions as vhl ligands and stat3 degraders uses thereof |
| CN117024254B (zh) * | 2023-08-10 | 2025-09-09 | 浙江大学衢州研究院 | 一种多氟苯酚的合成方法 |
| WO2026007994A1 (zh) * | 2024-07-03 | 2026-01-08 | 正大天晴药业集团股份有限公司 | 膦酸化合物及其用途 |
| WO2026020004A1 (en) * | 2024-07-19 | 2026-01-22 | Gilead Sciences, Inc. | Stat6 compounds |
| WO2026027675A1 (en) | 2024-07-31 | 2026-02-05 | Guerra Gonzalez Carmen | Triple combination for use in the treatmet of cancer |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019060742A1 (en) * | 2017-09-22 | 2019-03-28 | Kymera Therapeutics, Inc | AGENTS FOR DEGRADING PROTEINS AND USES THEREOF |
| WO2020198435A1 (en) * | 2019-03-26 | 2020-10-01 | The Regents Of The University Of Michigan | Small molecule degraders of stat3 |
| US12570679B2 (en) * | 2019-03-29 | 2026-03-10 | Regents Of The University Of Michigan | STAT3 protein degraders |
| CN120574283A (zh) * | 2019-04-05 | 2025-09-02 | 凯麦拉医疗公司 | Stat降解剂和其用途 |
-
2021
- 2021-03-17 CA CA3170503A patent/CA3170503A1/en active Pending
- 2021-03-17 AU AU2021238333A patent/AU2021238333A1/en not_active Abandoned
- 2021-03-17 MX MX2022011437A patent/MX2022011437A/es unknown
- 2021-03-17 US US17/912,388 patent/US20240016942A1/en active Pending
- 2021-03-17 WO PCT/US2021/022794 patent/WO2021188696A1/en not_active Ceased
- 2021-03-17 EP EP21771947.5A patent/EP4121055A4/en not_active Withdrawn
- 2021-03-17 CN CN202180032886.6A patent/CN115776891A/zh active Pending
- 2021-03-17 JP JP2022556046A patent/JP2023518422A/ja active Pending
- 2021-03-17 IL IL296334A patent/IL296334A/en unknown
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